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Cardiac telocytes are double positive for CD34/PDGFR-α.

Zhou Q, Wei L, Zhong C, Fu S, Bei Y, Huică RI, Wang F, Xiao J - J. Cell. Mol. Med. (2015)

Bottom Line: Telocytes (TCs) are a distinct type of interstitial cells, which are featured with a small cellular body and long and thin elongations called telopodes (Tps).TCs have been widely identified in lots of tissues and organs including heart.Better understanding of the immunocytochemical phenotypes of cardiac TCs might help using cardiac TCs as a novel source in cardiac repair.

View Article: PubMed Central - PubMed

Affiliation: Regeneration and Ageing Lab, Experimental Center of Life Sciences, School of Life Science, Shanghai University, Shanghai, China.

No MeSH data available.


CD34, PDGFR-α and PDGFR-β expression (positive cells percentages relative to the whole population in TC-enriched stromal cells from rat heart). The relative expression of three markers is shown for four experiments, as percentage of positive cells for CD34, PDGFR-α and PDGFR-β respectively, in relation to the whole (‘Parent’) cell population.
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fig07: CD34, PDGFR-α and PDGFR-β expression (positive cells percentages relative to the whole population in TC-enriched stromal cells from rat heart). The relative expression of three markers is shown for four experiments, as percentage of positive cells for CD34, PDGFR-α and PDGFR-β respectively, in relation to the whole (‘Parent’) cell population.

Mentions: CD34, PDGFR-α and PDGFR-β expression levels in the whole cell population are shown in Figure7 as percentage positive of the whole cell population. The PDGFR-α+ population varied from 80% to 91% of the total number of cells, with an average value of 87%. The CD34+/PDGFR-α+ population varied from 29% to 41%, while CD34+/PDGFR-β+ represented 28–36% (data not shown). The entire cell population shows a high expression level for PDGFR-α (‘bright’ events) and a lower expression level for CD34 and PDGFR-β (‘dim’ events; Fig.8). CD34/PDGFR-α positive events accounted for 30.25% of the cell population (data not shown).


Cardiac telocytes are double positive for CD34/PDGFR-α.

Zhou Q, Wei L, Zhong C, Fu S, Bei Y, Huică RI, Wang F, Xiao J - J. Cell. Mol. Med. (2015)

CD34, PDGFR-α and PDGFR-β expression (positive cells percentages relative to the whole population in TC-enriched stromal cells from rat heart). The relative expression of three markers is shown for four experiments, as percentage of positive cells for CD34, PDGFR-α and PDGFR-β respectively, in relation to the whole (‘Parent’) cell population.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4549054&req=5

fig07: CD34, PDGFR-α and PDGFR-β expression (positive cells percentages relative to the whole population in TC-enriched stromal cells from rat heart). The relative expression of three markers is shown for four experiments, as percentage of positive cells for CD34, PDGFR-α and PDGFR-β respectively, in relation to the whole (‘Parent’) cell population.
Mentions: CD34, PDGFR-α and PDGFR-β expression levels in the whole cell population are shown in Figure7 as percentage positive of the whole cell population. The PDGFR-α+ population varied from 80% to 91% of the total number of cells, with an average value of 87%. The CD34+/PDGFR-α+ population varied from 29% to 41%, while CD34+/PDGFR-β+ represented 28–36% (data not shown). The entire cell population shows a high expression level for PDGFR-α (‘bright’ events) and a lower expression level for CD34 and PDGFR-β (‘dim’ events; Fig.8). CD34/PDGFR-α positive events accounted for 30.25% of the cell population (data not shown).

Bottom Line: Telocytes (TCs) are a distinct type of interstitial cells, which are featured with a small cellular body and long and thin elongations called telopodes (Tps).TCs have been widely identified in lots of tissues and organs including heart.Better understanding of the immunocytochemical phenotypes of cardiac TCs might help using cardiac TCs as a novel source in cardiac repair.

View Article: PubMed Central - PubMed

Affiliation: Regeneration and Ageing Lab, Experimental Center of Life Sciences, School of Life Science, Shanghai University, Shanghai, China.

No MeSH data available.