Limits...
Cardiac telocytes are double positive for CD34/PDGFR-α.

Zhou Q, Wei L, Zhong C, Fu S, Bei Y, Huică RI, Wang F, Xiao J - J. Cell. Mol. Med. (2015)

Bottom Line: Telocytes (TCs) are a distinct type of interstitial cells, which are featured with a small cellular body and long and thin elongations called telopodes (Tps).TCs have been widely identified in lots of tissues and organs including heart.Better understanding of the immunocytochemical phenotypes of cardiac TCs might help using cardiac TCs as a novel source in cardiac repair.

View Article: PubMed Central - PubMed

Affiliation: Regeneration and Ageing Lab, Experimental Center of Life Sciences, School of Life Science, Shanghai University, Shanghai, China.

No MeSH data available.


CD34/PDGFR-α positive cells (putative cardiac TCs) exist in mice ventricle. Double immunofluorescence labelling for CD34 (green) and PDGFR-α (red) with DAPI (blue) counterstain for nuclei shows that CD34/PDGFR-α positive cells (putative cardiac TCs) exist in mice ventricle; scale bar = 20 μm.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4549054&req=5

fig04: CD34/PDGFR-α positive cells (putative cardiac TCs) exist in mice ventricle. Double immunofluorescence labelling for CD34 (green) and PDGFR-α (red) with DAPI (blue) counterstain for nuclei shows that CD34/PDGFR-α positive cells (putative cardiac TCs) exist in mice ventricle; scale bar = 20 μm.

Mentions: To further explore if CD34/PDGFR-α positive cells (putative cardiac TCs) exist, we checked the samples from mice ventricle firstly. We identified CD34/PDGFR-α positive cells (putative cardiac TCs) in mice ventricle (Fig.4). Besides, we also explored their existence in human cardiac valves. We found that CD34/PDGFR-α positive cells (putative cardiac TCs) existed in human cardiac valves including mitral valve, tricuspid valve and aortic valve (Fig.5).


Cardiac telocytes are double positive for CD34/PDGFR-α.

Zhou Q, Wei L, Zhong C, Fu S, Bei Y, Huică RI, Wang F, Xiao J - J. Cell. Mol. Med. (2015)

CD34/PDGFR-α positive cells (putative cardiac TCs) exist in mice ventricle. Double immunofluorescence labelling for CD34 (green) and PDGFR-α (red) with DAPI (blue) counterstain for nuclei shows that CD34/PDGFR-α positive cells (putative cardiac TCs) exist in mice ventricle; scale bar = 20 μm.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4549054&req=5

fig04: CD34/PDGFR-α positive cells (putative cardiac TCs) exist in mice ventricle. Double immunofluorescence labelling for CD34 (green) and PDGFR-α (red) with DAPI (blue) counterstain for nuclei shows that CD34/PDGFR-α positive cells (putative cardiac TCs) exist in mice ventricle; scale bar = 20 μm.
Mentions: To further explore if CD34/PDGFR-α positive cells (putative cardiac TCs) exist, we checked the samples from mice ventricle firstly. We identified CD34/PDGFR-α positive cells (putative cardiac TCs) in mice ventricle (Fig.4). Besides, we also explored their existence in human cardiac valves. We found that CD34/PDGFR-α positive cells (putative cardiac TCs) existed in human cardiac valves including mitral valve, tricuspid valve and aortic valve (Fig.5).

Bottom Line: Telocytes (TCs) are a distinct type of interstitial cells, which are featured with a small cellular body and long and thin elongations called telopodes (Tps).TCs have been widely identified in lots of tissues and organs including heart.Better understanding of the immunocytochemical phenotypes of cardiac TCs might help using cardiac TCs as a novel source in cardiac repair.

View Article: PubMed Central - PubMed

Affiliation: Regeneration and Ageing Lab, Experimental Center of Life Sciences, School of Life Science, Shanghai University, Shanghai, China.

No MeSH data available.