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Outcomes of Patients With Acute Type B (DeBakey III) Aortic Dissection: A 13-Year, Single-Center Experience.

Afifi RO, Sandhu HK, Leake SS, Boutrous ML, Kumar V, Azizzadeh A, Charlton-Ouw KM, Saqib NU, Nguyen TC, Miller CC, Safi HJ, Estrera AL - Circulation (2015)

Bottom Line: Outcomes were compared between the groups by use of Kaplan-Meier and descriptive statistics.Overall survival was significantly related primarily to complicated presentation.Although uATBAD was associated with favorable early survival, late complications still occurred, mandating radiographic surveillance and open or endovascular interventions.

View Article: PubMed Central - PubMed

Affiliation: From the University of Texas Medical School at Houston and Memorial Hermann Heart & Vascular Institute, Houston.

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Related in: MedlinePlus

Reintervention-free survival by complicated presentation and treatment. C-Med indicates complicated patients treated with medical therapy; C-Open, complicated patients treated with open peripheral vascular procedures; and C-TEVAR, complicated patients treated with thoracic endovascular aortic repair. *The 17 patients in the C-Open group were included in the survival analysis but were removed from this graph for the sake of clarity, given the number of graph lines.
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Figure 2: Reintervention-free survival by complicated presentation and treatment. C-Med indicates complicated patients treated with medical therapy; C-Open, complicated patients treated with open peripheral vascular procedures; and C-TEVAR, complicated patients treated with thoracic endovascular aortic repair. *The 17 patients in the C-Open group were included in the survival analysis but were removed from this graph for the sake of clarity, given the number of graph lines.

Mentions: Median follow-up time was 4.6 years (range, 1.9ā€“7.8 years). The longest follow-up available in TEVAR group was 7.5 years. Loss to follow-up for long-term reintervention for the overall cohort was 22%. Sensitivity analysis for long-term reintervention among patients with incomplete follow-up demonstrated a 4.7% increase in possible reinterventions across the board in the most extreme case (all noncontacted patients assumed failed), but with minimal (<3.5% change) to the survival standard error (P=0.50). Intervention-free survival differed significantly between uncomplicated (84.8% and 62.7% at 1 and 5 years, respectively) and complicated (66.6% and 44.3% at 1 and 5 years, respectively) presentations (P<0.0001; Figure 2). Some variation among the treatment groups in the complicated subjects was evident, with TEVAR approaching a lower reintervention-free survival (Pā‰ˆ0.07; Tables 3 and 4).


Outcomes of Patients With Acute Type B (DeBakey III) Aortic Dissection: A 13-Year, Single-Center Experience.

Afifi RO, Sandhu HK, Leake SS, Boutrous ML, Kumar V, Azizzadeh A, Charlton-Ouw KM, Saqib NU, Nguyen TC, Miller CC, Safi HJ, Estrera AL - Circulation (2015)

Reintervention-free survival by complicated presentation and treatment. C-Med indicates complicated patients treated with medical therapy; C-Open, complicated patients treated with open peripheral vascular procedures; and C-TEVAR, complicated patients treated with thoracic endovascular aortic repair. *The 17 patients in the C-Open group were included in the survival analysis but were removed from this graph for the sake of clarity, given the number of graph lines.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4548541&req=5

Figure 2: Reintervention-free survival by complicated presentation and treatment. C-Med indicates complicated patients treated with medical therapy; C-Open, complicated patients treated with open peripheral vascular procedures; and C-TEVAR, complicated patients treated with thoracic endovascular aortic repair. *The 17 patients in the C-Open group were included in the survival analysis but were removed from this graph for the sake of clarity, given the number of graph lines.
Mentions: Median follow-up time was 4.6 years (range, 1.9ā€“7.8 years). The longest follow-up available in TEVAR group was 7.5 years. Loss to follow-up for long-term reintervention for the overall cohort was 22%. Sensitivity analysis for long-term reintervention among patients with incomplete follow-up demonstrated a 4.7% increase in possible reinterventions across the board in the most extreme case (all noncontacted patients assumed failed), but with minimal (<3.5% change) to the survival standard error (P=0.50). Intervention-free survival differed significantly between uncomplicated (84.8% and 62.7% at 1 and 5 years, respectively) and complicated (66.6% and 44.3% at 1 and 5 years, respectively) presentations (P<0.0001; Figure 2). Some variation among the treatment groups in the complicated subjects was evident, with TEVAR approaching a lower reintervention-free survival (Pā‰ˆ0.07; Tables 3 and 4).

Bottom Line: Outcomes were compared between the groups by use of Kaplan-Meier and descriptive statistics.Overall survival was significantly related primarily to complicated presentation.Although uATBAD was associated with favorable early survival, late complications still occurred, mandating radiographic surveillance and open or endovascular interventions.

View Article: PubMed Central - PubMed

Affiliation: From the University of Texas Medical School at Houston and Memorial Hermann Heart & Vascular Institute, Houston.

Show MeSH
Related in: MedlinePlus