Limits...
Lecithin-based wet chemical precipitation of hydroxyapatite nanoparticles.

Michał W, Ewa D, Tomasz C - Colloid Polym Sci (2015)

Bottom Line: Size distribution for nanoparticles was measured by nanoparticle tracking analysis in NanoSight system.We discuss in details influence of lecithin concentration in reaction system on nHAp-PC morphology, as well as on size distributions and suspendability of nanoparticles.Difference in surfactant amounts results in changes in particles morphology and their average size.

View Article: PubMed Central - PubMed

Affiliation: BioMedical Engineering Laboratory, Faculty of Chemical and Process Engineering, Warsaw University of Technology, Waryńskiego 1, 00-645 Warszawa, Poland.

ABSTRACT

Hydroxyapatite Ca10(PO4)6(OH)2 nanoparticles have been successfully synthesized by the wet chemical precipitation method at 60 °C in the presence of biocompatible natural surfactant-lecithin. The composition and morphology of nanoparticles of hydroxyapatite synthesized with lecithin (nHAp-PC) was studied by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM). Size distribution for nanoparticles was measured by nanoparticle tracking analysis in NanoSight system. We discuss in details influence of lecithin concentration in reaction system on nHAp-PC morphology, as well as on size distributions and suspendability of nanoparticles. Product exhibits crystalline structure and chemical composition of hydroxyapatite, with visible traces of lecithin. Difference in surfactant amounts results in changes in particles morphology and their average size.

No MeSH data available.


Related in: MedlinePlus

FTIR spectra of lecithin-based (3.00 % w/w) wet chemical precipitation synthesized hydroxyapatite nanoparticles (nHAp-PC), commercially sourced hydroxyapatite nanoparticles (nHAp), and pure soybean lecithin
© Copyright Policy - OpenAccess
Related In: Results  -  Collection


getmorefigures.php?uid=PMC4544500&req=5

Fig2: FTIR spectra of lecithin-based (3.00 % w/w) wet chemical precipitation synthesized hydroxyapatite nanoparticles (nHAp-PC), commercially sourced hydroxyapatite nanoparticles (nHAp), and pure soybean lecithin

Mentions: FTIR analysis of nHAp-PC shows peaks position consistent with commercially available hydroxyapatite (Fig. 2). The strongest, characteristic peak for nHAp derived from PO43− appears at position of 1,030 cm−1 for commercially available nHAp and nHAp-PC produced in lecithin-based wet chemical precipitation. Peaks derived from P-O stretching bonds appear at 570 and 609 cm−1 for nHAp and nHAp-PC, which indicate correspondence and chemical similarity of commercially available hydroxyapatite and hydroxyapatite synthesized in the presence of lecithin. Spectra of lecithin shows peak from C = O stretching bonds in ester groups at 1,737 cm−1, peaks from C-O stretching bond at 1,376 and 1,227 cm−1, and peaks from C-H bond of fatty-acid’s long chains at 2,852 and 2,921 cm−1 (Fig. 2). The weak bands corresponding to lecithin appear in nHAp-PC spectra, which suggest presence of lecithin bonded to the surface of the final product. The effect of surfactant bonding to the resulting nanoparticles is established in literature. Liu et al. [9] reported presence of residues of cetyltrimethylammonium bromide (CTAB)—toxic surfactant—in hydroxyapatite nanoparticles synthesized in wet chemical precipitation. Apart from lecithin presence, the results of chemical composition analysis of nHAp-PC are comparable with results obtained for other methods for synthesis of nanoparticles of hydroxyapatite [20, 23]. Biocompatibility of lecithin is well established in the literature [24, 25]; thus, its presence in the synthesized nHAp-PC might be preferable for its biomedical applications.Fig. 2


Lecithin-based wet chemical precipitation of hydroxyapatite nanoparticles.

Michał W, Ewa D, Tomasz C - Colloid Polym Sci (2015)

FTIR spectra of lecithin-based (3.00 % w/w) wet chemical precipitation synthesized hydroxyapatite nanoparticles (nHAp-PC), commercially sourced hydroxyapatite nanoparticles (nHAp), and pure soybean lecithin
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4544500&req=5

Fig2: FTIR spectra of lecithin-based (3.00 % w/w) wet chemical precipitation synthesized hydroxyapatite nanoparticles (nHAp-PC), commercially sourced hydroxyapatite nanoparticles (nHAp), and pure soybean lecithin
Mentions: FTIR analysis of nHAp-PC shows peaks position consistent with commercially available hydroxyapatite (Fig. 2). The strongest, characteristic peak for nHAp derived from PO43− appears at position of 1,030 cm−1 for commercially available nHAp and nHAp-PC produced in lecithin-based wet chemical precipitation. Peaks derived from P-O stretching bonds appear at 570 and 609 cm−1 for nHAp and nHAp-PC, which indicate correspondence and chemical similarity of commercially available hydroxyapatite and hydroxyapatite synthesized in the presence of lecithin. Spectra of lecithin shows peak from C = O stretching bonds in ester groups at 1,737 cm−1, peaks from C-O stretching bond at 1,376 and 1,227 cm−1, and peaks from C-H bond of fatty-acid’s long chains at 2,852 and 2,921 cm−1 (Fig. 2). The weak bands corresponding to lecithin appear in nHAp-PC spectra, which suggest presence of lecithin bonded to the surface of the final product. The effect of surfactant bonding to the resulting nanoparticles is established in literature. Liu et al. [9] reported presence of residues of cetyltrimethylammonium bromide (CTAB)—toxic surfactant—in hydroxyapatite nanoparticles synthesized in wet chemical precipitation. Apart from lecithin presence, the results of chemical composition analysis of nHAp-PC are comparable with results obtained for other methods for synthesis of nanoparticles of hydroxyapatite [20, 23]. Biocompatibility of lecithin is well established in the literature [24, 25]; thus, its presence in the synthesized nHAp-PC might be preferable for its biomedical applications.Fig. 2

Bottom Line: Size distribution for nanoparticles was measured by nanoparticle tracking analysis in NanoSight system.We discuss in details influence of lecithin concentration in reaction system on nHAp-PC morphology, as well as on size distributions and suspendability of nanoparticles.Difference in surfactant amounts results in changes in particles morphology and their average size.

View Article: PubMed Central - PubMed

Affiliation: BioMedical Engineering Laboratory, Faculty of Chemical and Process Engineering, Warsaw University of Technology, Waryńskiego 1, 00-645 Warszawa, Poland.

ABSTRACT

Hydroxyapatite Ca10(PO4)6(OH)2 nanoparticles have been successfully synthesized by the wet chemical precipitation method at 60 °C in the presence of biocompatible natural surfactant-lecithin. The composition and morphology of nanoparticles of hydroxyapatite synthesized with lecithin (nHAp-PC) was studied by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM). Size distribution for nanoparticles was measured by nanoparticle tracking analysis in NanoSight system. We discuss in details influence of lecithin concentration in reaction system on nHAp-PC morphology, as well as on size distributions and suspendability of nanoparticles. Product exhibits crystalline structure and chemical composition of hydroxyapatite, with visible traces of lecithin. Difference in surfactant amounts results in changes in particles morphology and their average size.

No MeSH data available.


Related in: MedlinePlus