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Lecithin-based wet chemical precipitation of hydroxyapatite nanoparticles.

Michał W, Ewa D, Tomasz C - Colloid Polym Sci (2015)

Bottom Line: Size distribution for nanoparticles was measured by nanoparticle tracking analysis in NanoSight system.We discuss in details influence of lecithin concentration in reaction system on nHAp-PC morphology, as well as on size distributions and suspendability of nanoparticles.Difference in surfactant amounts results in changes in particles morphology and their average size.

View Article: PubMed Central - PubMed

Affiliation: BioMedical Engineering Laboratory, Faculty of Chemical and Process Engineering, Warsaw University of Technology, Waryńskiego 1, 00-645 Warszawa, Poland.

ABSTRACT

Hydroxyapatite Ca10(PO4)6(OH)2 nanoparticles have been successfully synthesized by the wet chemical precipitation method at 60 °C in the presence of biocompatible natural surfactant-lecithin. The composition and morphology of nanoparticles of hydroxyapatite synthesized with lecithin (nHAp-PC) was studied by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM). Size distribution for nanoparticles was measured by nanoparticle tracking analysis in NanoSight system. We discuss in details influence of lecithin concentration in reaction system on nHAp-PC morphology, as well as on size distributions and suspendability of nanoparticles. Product exhibits crystalline structure and chemical composition of hydroxyapatite, with visible traces of lecithin. Difference in surfactant amounts results in changes in particles morphology and their average size.

No MeSH data available.


Related in: MedlinePlus

XRD patterns of commercially available hydroxyapatite powder (nHAp) and hydroxyapatite nanoparticles (nHAp-PC) synthesized with 3.00 % w/w lecithin
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Fig1: XRD patterns of commercially available hydroxyapatite powder (nHAp) and hydroxyapatite nanoparticles (nHAp-PC) synthesized with 3.00 % w/w lecithin

Mentions: The XRD diffraction pattern of nHAp-PC synthesized in the presence of lecithin and diffraction pattern of commercially available nHAp are shown in Fig. 1. Comparison with XRD pattern of nHAp and data in standard JCPDS file no. 09-0432 obtained for pure crystalline hydroxyapatite proved consistency between two samples. Some differences in peak intensity and positions between analyzed nHAp-PC sample and commercial nHAp, as well as literature reference, might be caused by: (1) amorphous structure, (2) preferred orientation of small crystallites in studied powder; (3) crystallites shape anisotropy—different size in different crystalline directions; (4) crystallites microstress anisotropy—atomic systematic displacement in lattice node; and (5) presence of lecithin bonded to surface of the nHAp-PC. Despite the fact of those slight differences in the crystallinity of nHAp-PC comparing to commercial nHAp, and HAp form data file, the structure of nHAp-PC corresponds with previously reported hydroxyapatite nanoparticles obtained in different manners [9, 12, 20].Fig. 1


Lecithin-based wet chemical precipitation of hydroxyapatite nanoparticles.

Michał W, Ewa D, Tomasz C - Colloid Polym Sci (2015)

XRD patterns of commercially available hydroxyapatite powder (nHAp) and hydroxyapatite nanoparticles (nHAp-PC) synthesized with 3.00 % w/w lecithin
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4544500&req=5

Fig1: XRD patterns of commercially available hydroxyapatite powder (nHAp) and hydroxyapatite nanoparticles (nHAp-PC) synthesized with 3.00 % w/w lecithin
Mentions: The XRD diffraction pattern of nHAp-PC synthesized in the presence of lecithin and diffraction pattern of commercially available nHAp are shown in Fig. 1. Comparison with XRD pattern of nHAp and data in standard JCPDS file no. 09-0432 obtained for pure crystalline hydroxyapatite proved consistency between two samples. Some differences in peak intensity and positions between analyzed nHAp-PC sample and commercial nHAp, as well as literature reference, might be caused by: (1) amorphous structure, (2) preferred orientation of small crystallites in studied powder; (3) crystallites shape anisotropy—different size in different crystalline directions; (4) crystallites microstress anisotropy—atomic systematic displacement in lattice node; and (5) presence of lecithin bonded to surface of the nHAp-PC. Despite the fact of those slight differences in the crystallinity of nHAp-PC comparing to commercial nHAp, and HAp form data file, the structure of nHAp-PC corresponds with previously reported hydroxyapatite nanoparticles obtained in different manners [9, 12, 20].Fig. 1

Bottom Line: Size distribution for nanoparticles was measured by nanoparticle tracking analysis in NanoSight system.We discuss in details influence of lecithin concentration in reaction system on nHAp-PC morphology, as well as on size distributions and suspendability of nanoparticles.Difference in surfactant amounts results in changes in particles morphology and their average size.

View Article: PubMed Central - PubMed

Affiliation: BioMedical Engineering Laboratory, Faculty of Chemical and Process Engineering, Warsaw University of Technology, Waryńskiego 1, 00-645 Warszawa, Poland.

ABSTRACT

Hydroxyapatite Ca10(PO4)6(OH)2 nanoparticles have been successfully synthesized by the wet chemical precipitation method at 60 °C in the presence of biocompatible natural surfactant-lecithin. The composition and morphology of nanoparticles of hydroxyapatite synthesized with lecithin (nHAp-PC) was studied by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM). Size distribution for nanoparticles was measured by nanoparticle tracking analysis in NanoSight system. We discuss in details influence of lecithin concentration in reaction system on nHAp-PC morphology, as well as on size distributions and suspendability of nanoparticles. Product exhibits crystalline structure and chemical composition of hydroxyapatite, with visible traces of lecithin. Difference in surfactant amounts results in changes in particles morphology and their average size.

No MeSH data available.


Related in: MedlinePlus