Limits...
Prevalence of hepatitis C virus in Brazil's inmate population: a systematic review.

Magri MC, Ibrahim KY, Pinto WP, França FO, Bernardo WM, Tengan FM - Rev Saude Publica (2015)

Bottom Line: The methodological quality of the studies was assessed using a scale of 0 to 8 points.The four studies conducted in the city of Sao Paulo revealed a lower prevalence in more recent studies compared to older ones.CONCLUSIONS The highest prevalence of hepatitis C virus infection in Brazil's inmate population was found in Sao Paulo, which may reflect the urban diversity of the country.

View Article: PubMed Central - PubMed

Affiliation: Laboratório de Investigação Médica em Hepatologia por Vírus, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil.

ABSTRACT
OBJECTIVE To estimate the prevalence of hepatitis C virus infection in Brazil's inmate population. METHODS Systematic review on hepatitis C virus infection in the inmate population. Brazilian studies published from January 1, 1989 to February 20, 2014 were evaluated. The methodological quality of the studies was assessed using a scale of 0 to 8 points. RESULTS Eleven eligible studies were analyzed and provided data on hepatitis C virus infection among 4,375 inmates from seven states of Brazil, with a mean quality classification of 7.4. The overall hepatitis C virus prevalence among Brazilian inmates was 13.6% (ranging from 1.0% to 41.0%, depending on the study). The chances of inmates being seropositive for hepatitis C virus in the states of Minas Gerais (MG), Sergipe (SE), Mato Grosso do Sul (MS), Rio Grande do Sul (RS), Goiás (GO) and Espirito Santo (ES) were 84.0% (95%CI 0.06;0.45), 92.0% (95%CI 0.04;0.13), 88.0% (95%CI 0.09;0.18), 74.0% (95%CI 0.16;0.42), 84.0% (95%CI 0.08;0.31) and 89.0% (95%CI 0.01;0.05) respectively, lower than that observed in the Sao Paulo state (seroprevalence of 29.3%). The four studies conducted in the city of Sao Paulo revealed a lower prevalence in more recent studies compared to older ones. CONCLUSIONS The highest prevalence of hepatitis C virus infection in Brazil's inmate population was found in Sao Paulo, which may reflect the urban diversity of the country. Despite Brazilian studies having good methodological quality to evaluate the prevalence of the hepatitis C virus, they are scarce and lack data on risk factors associated with this infection, which could support decisions on prevention and implementation of public health policies for Brazilian prisons.

No MeSH data available.


Related in: MedlinePlus

Flowchart of study selection in the different phases of the systematic review.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4544450&req=5

f01: Flowchart of study selection in the different phases of the systematic review.

Mentions: Using the initial literature search strategies, we identified 50 studies, including 25 duplicates. After reading the abstracts, 11 were excluded. Thus, the full texts of 14 articles were reviewed, all of them available in English, and three of them were excluded (Figure). The studies by Fialho et al13 and Zanetta et al48 were excluded in full text review because they included inmates younger than 18 years of age. The study by Strazza et al39 from 2004 was excluded because it included samples from the same prison as the study by Strazza et al40 from 2007, which provided detailed information and therefore was included.


Prevalence of hepatitis C virus in Brazil's inmate population: a systematic review.

Magri MC, Ibrahim KY, Pinto WP, França FO, Bernardo WM, Tengan FM - Rev Saude Publica (2015)

Flowchart of study selection in the different phases of the systematic review.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4544450&req=5

f01: Flowchart of study selection in the different phases of the systematic review.
Mentions: Using the initial literature search strategies, we identified 50 studies, including 25 duplicates. After reading the abstracts, 11 were excluded. Thus, the full texts of 14 articles were reviewed, all of them available in English, and three of them were excluded (Figure). The studies by Fialho et al13 and Zanetta et al48 were excluded in full text review because they included inmates younger than 18 years of age. The study by Strazza et al39 from 2004 was excluded because it included samples from the same prison as the study by Strazza et al40 from 2007, which provided detailed information and therefore was included.

Bottom Line: The methodological quality of the studies was assessed using a scale of 0 to 8 points.The four studies conducted in the city of Sao Paulo revealed a lower prevalence in more recent studies compared to older ones.CONCLUSIONS The highest prevalence of hepatitis C virus infection in Brazil's inmate population was found in Sao Paulo, which may reflect the urban diversity of the country.

View Article: PubMed Central - PubMed

Affiliation: Laboratório de Investigação Médica em Hepatologia por Vírus, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil.

ABSTRACT
OBJECTIVE To estimate the prevalence of hepatitis C virus infection in Brazil's inmate population. METHODS Systematic review on hepatitis C virus infection in the inmate population. Brazilian studies published from January 1, 1989 to February 20, 2014 were evaluated. The methodological quality of the studies was assessed using a scale of 0 to 8 points. RESULTS Eleven eligible studies were analyzed and provided data on hepatitis C virus infection among 4,375 inmates from seven states of Brazil, with a mean quality classification of 7.4. The overall hepatitis C virus prevalence among Brazilian inmates was 13.6% (ranging from 1.0% to 41.0%, depending on the study). The chances of inmates being seropositive for hepatitis C virus in the states of Minas Gerais (MG), Sergipe (SE), Mato Grosso do Sul (MS), Rio Grande do Sul (RS), Goiás (GO) and Espirito Santo (ES) were 84.0% (95%CI 0.06;0.45), 92.0% (95%CI 0.04;0.13), 88.0% (95%CI 0.09;0.18), 74.0% (95%CI 0.16;0.42), 84.0% (95%CI 0.08;0.31) and 89.0% (95%CI 0.01;0.05) respectively, lower than that observed in the Sao Paulo state (seroprevalence of 29.3%). The four studies conducted in the city of Sao Paulo revealed a lower prevalence in more recent studies compared to older ones. CONCLUSIONS The highest prevalence of hepatitis C virus infection in Brazil's inmate population was found in Sao Paulo, which may reflect the urban diversity of the country. Despite Brazilian studies having good methodological quality to evaluate the prevalence of the hepatitis C virus, they are scarce and lack data on risk factors associated with this infection, which could support decisions on prevention and implementation of public health policies for Brazilian prisons.

No MeSH data available.


Related in: MedlinePlus