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The predicting ability of serum potassium to assess the duration of mechanical ventilation in critically ill patients.

Javdan Z, Talakoub R, Honarmand A, Golparvar M, Farsani EY - Adv Biomed Res (2015)

Bottom Line: There was no significant difference between the Serum K concentrations between the two groups, on admission.However, there were significant difference between the Serum K concentrations at times of receiving and weaning from mechanical ventilation (MV) between the two groups.Development of hypokalemia during an ICU stay is associated with the need for mechanical ventilation.

View Article: PubMed Central - PubMed

Affiliation: Department of Anesthesiology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

ABSTRACT

Background: No previous study has been done to evaluate the admission serum potassium level as a predictor of morbidity or need for mechanical ventilation. The aim of this study is to determine the predictive ability of serum potassium on admission, in critically ill trauma patients, and to evaluate the relation of the potassium level to organ failure, length of stay, ventilator need, and duration of mechanical ventilation.

Materials and methods: A prospective, observational study was done on 100 patients >16 years old, admitted to the Medical-Surgical Intensive Care Units (ICU), for over one year. Patients were classified into Group A: Patients who required equal or less than five days of mechanical ventilation and Group B: Patients who required more than five days of mechanical ventilation. The total serum potassium concentrations were measured and the Sequential Organ Failure Assessment (SOFA) score was recorded at the time of admission to the ICU, when connected to the ventilator, and then at the time of weaning from the ventilator.

Results: There was no significant difference between the Serum K concentrations between the two groups, on admission. However, there were significant difference between the Serum K concentrations at times of receiving and weaning from mechanical ventilation (MV) between the two groups. We found the best cut-off point of 3.45 for serum potassium concentration, to predict the need for longer duration of MV.

Conclusion: Development of hypokalemia during an ICU stay is associated with the need for mechanical ventilation. Monitoring of the serum potassium levels may be a good prognostic factor for the requirement of mechanical ventilation.

No MeSH data available.


Related in: MedlinePlus

Receiver Operating Characteristic (ROC) curves show need for longer mechanical ventilation drawn of Serum K concentration on admission (curve a), SOFA score on admission (curve b) and SOFA score at receiving MV (curve c)
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Figure 1: Receiver Operating Characteristic (ROC) curves show need for longer mechanical ventilation drawn of Serum K concentration on admission (curve a), SOFA score on admission (curve b) and SOFA score at receiving MV (curve c)

Mentions: We used ROC curves of the Serum K concentrations and SOFA scores to find a best cut-off point as a prediction factor for a need for longer MV. The sensitivity, specificity, and area of the ROC curve at the best cut-off point for longer MV are presented in Table 3 and Figure 1.


The predicting ability of serum potassium to assess the duration of mechanical ventilation in critically ill patients.

Javdan Z, Talakoub R, Honarmand A, Golparvar M, Farsani EY - Adv Biomed Res (2015)

Receiver Operating Characteristic (ROC) curves show need for longer mechanical ventilation drawn of Serum K concentration on admission (curve a), SOFA score on admission (curve b) and SOFA score at receiving MV (curve c)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4544123&req=5

Figure 1: Receiver Operating Characteristic (ROC) curves show need for longer mechanical ventilation drawn of Serum K concentration on admission (curve a), SOFA score on admission (curve b) and SOFA score at receiving MV (curve c)
Mentions: We used ROC curves of the Serum K concentrations and SOFA scores to find a best cut-off point as a prediction factor for a need for longer MV. The sensitivity, specificity, and area of the ROC curve at the best cut-off point for longer MV are presented in Table 3 and Figure 1.

Bottom Line: There was no significant difference between the Serum K concentrations between the two groups, on admission.However, there were significant difference between the Serum K concentrations at times of receiving and weaning from mechanical ventilation (MV) between the two groups.Development of hypokalemia during an ICU stay is associated with the need for mechanical ventilation.

View Article: PubMed Central - PubMed

Affiliation: Department of Anesthesiology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

ABSTRACT

Background: No previous study has been done to evaluate the admission serum potassium level as a predictor of morbidity or need for mechanical ventilation. The aim of this study is to determine the predictive ability of serum potassium on admission, in critically ill trauma patients, and to evaluate the relation of the potassium level to organ failure, length of stay, ventilator need, and duration of mechanical ventilation.

Materials and methods: A prospective, observational study was done on 100 patients >16 years old, admitted to the Medical-Surgical Intensive Care Units (ICU), for over one year. Patients were classified into Group A: Patients who required equal or less than five days of mechanical ventilation and Group B: Patients who required more than five days of mechanical ventilation. The total serum potassium concentrations were measured and the Sequential Organ Failure Assessment (SOFA) score was recorded at the time of admission to the ICU, when connected to the ventilator, and then at the time of weaning from the ventilator.

Results: There was no significant difference between the Serum K concentrations between the two groups, on admission. However, there were significant difference between the Serum K concentrations at times of receiving and weaning from mechanical ventilation (MV) between the two groups. We found the best cut-off point of 3.45 for serum potassium concentration, to predict the need for longer duration of MV.

Conclusion: Development of hypokalemia during an ICU stay is associated with the need for mechanical ventilation. Monitoring of the serum potassium levels may be a good prognostic factor for the requirement of mechanical ventilation.

No MeSH data available.


Related in: MedlinePlus