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Effects of TCMC on Transformation of Good Health Status to Suboptimal Health Status: A Nested Case-Control Study.

Wang T, Chen J, Sun X, Xiang L, Zhou L, Li F, Lin C, Jiang P, Wu S, Xiao Y, Cheng J, Luo R, Liu Y, Zhao X - Evid Based Complement Alternat Med (2015)

Bottom Line: There was a significant (P = 0.000) and marked reduction in SHMS V1.0 total score in the case group at the 18-month follow-up (69.32 ± 5.45) compared with baseline (78.60 ± 4.70), but there was no significant change in the control group.However, the Balanced Constitution was a significant protective factor (OR 0.649; P < 0.05).We conclude that regulating the unbalanced TCMC (such as Yin-deficiency and Qi-deficiency) may prevent a healthy status developing into SHS or lead to the regression of SHS.

View Article: PubMed Central - PubMed

Affiliation: Department of Traditional Chinese Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China ; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong 510515, China.

ABSTRACT
To explore the effects of traditional Chinese medicine constitution (TCMC) on transformation of good health status to suboptimal health status (SHS), we conducted a nested case-control study among college students in China. During the 18-month mean follow-up time, 543 cases of SHS (42.7%) occurred in 1273 healthy students. There was a significant (P = 0.000) and marked reduction in SHMS V1.0 total score in the case group at the 18-month follow-up (69.32 ± 5.45) compared with baseline (78.60 ± 4.70), but there was no significant change in the control group. Conditional logistic regression analysis showed that respondents reporting Yin-deficiency and Qi-deficiency were, respectively, 2.247 and 2.198 times more likely to develop SHS, while tendency to Yin-deficiency and tendency to Damp-heat were, respectively, 1.642 and 1.506 times more likely to develop SHS. However, the Balanced Constitution was a significant protective factor (OR 0.649; P < 0.05). Altogether, these findings demonstrate that Yin-deficiency, Qi-deficiency, tendency to Yin-deficiency, and tendency to Damp-heat appeared to induce a change in health status to SHS, while the Balanced Constitution seemed to restrain this change. We conclude that regulating the unbalanced TCMC (such as Yin-deficiency and Qi-deficiency) may prevent a healthy status developing into SHS or lead to the regression of SHS.

No MeSH data available.


Related in: MedlinePlus

Flow of eligible participants in study.
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fig1: Flow of eligible participants in study.

Mentions: The subjects in this nested case-control study were identified from an existing clinic-based cohort established at the Nanfang Hospital in Guangzhou and were consecutively enrolled from the cohort of college students who signed the informed consent form March 2013 to May 2013. Of these, 311 students had to move elsewhere and thus dropped out of the study. In total, 5676 students (1973 men and 3703 women) attended a health examination in the hospital, which included medical history-taking, physical examination, blood hematology and biochemistry analyses, resting electrocardiography, abdominal ultrasonography, and chest radiography. The diagnosis of disease was based on clinical criteria. Any participants diagnosed with clinical disease during the health examination (1431 students) were excluded. The medical report and the Suboptimal Health Measurement Scale Version 1.0 (SHMS V1.0) were used to evaluate health status, and any participants with SHS (2972 students) were also excluded. The detailed process is shown in Figure 1.


Effects of TCMC on Transformation of Good Health Status to Suboptimal Health Status: A Nested Case-Control Study.

Wang T, Chen J, Sun X, Xiang L, Zhou L, Li F, Lin C, Jiang P, Wu S, Xiao Y, Cheng J, Luo R, Liu Y, Zhao X - Evid Based Complement Alternat Med (2015)

Flow of eligible participants in study.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4543579&req=5

fig1: Flow of eligible participants in study.
Mentions: The subjects in this nested case-control study were identified from an existing clinic-based cohort established at the Nanfang Hospital in Guangzhou and were consecutively enrolled from the cohort of college students who signed the informed consent form March 2013 to May 2013. Of these, 311 students had to move elsewhere and thus dropped out of the study. In total, 5676 students (1973 men and 3703 women) attended a health examination in the hospital, which included medical history-taking, physical examination, blood hematology and biochemistry analyses, resting electrocardiography, abdominal ultrasonography, and chest radiography. The diagnosis of disease was based on clinical criteria. Any participants diagnosed with clinical disease during the health examination (1431 students) were excluded. The medical report and the Suboptimal Health Measurement Scale Version 1.0 (SHMS V1.0) were used to evaluate health status, and any participants with SHS (2972 students) were also excluded. The detailed process is shown in Figure 1.

Bottom Line: There was a significant (P = 0.000) and marked reduction in SHMS V1.0 total score in the case group at the 18-month follow-up (69.32 ± 5.45) compared with baseline (78.60 ± 4.70), but there was no significant change in the control group.However, the Balanced Constitution was a significant protective factor (OR 0.649; P < 0.05).We conclude that regulating the unbalanced TCMC (such as Yin-deficiency and Qi-deficiency) may prevent a healthy status developing into SHS or lead to the regression of SHS.

View Article: PubMed Central - PubMed

Affiliation: Department of Traditional Chinese Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, China ; School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong 510515, China.

ABSTRACT
To explore the effects of traditional Chinese medicine constitution (TCMC) on transformation of good health status to suboptimal health status (SHS), we conducted a nested case-control study among college students in China. During the 18-month mean follow-up time, 543 cases of SHS (42.7%) occurred in 1273 healthy students. There was a significant (P = 0.000) and marked reduction in SHMS V1.0 total score in the case group at the 18-month follow-up (69.32 ± 5.45) compared with baseline (78.60 ± 4.70), but there was no significant change in the control group. Conditional logistic regression analysis showed that respondents reporting Yin-deficiency and Qi-deficiency were, respectively, 2.247 and 2.198 times more likely to develop SHS, while tendency to Yin-deficiency and tendency to Damp-heat were, respectively, 1.642 and 1.506 times more likely to develop SHS. However, the Balanced Constitution was a significant protective factor (OR 0.649; P < 0.05). Altogether, these findings demonstrate that Yin-deficiency, Qi-deficiency, tendency to Yin-deficiency, and tendency to Damp-heat appeared to induce a change in health status to SHS, while the Balanced Constitution seemed to restrain this change. We conclude that regulating the unbalanced TCMC (such as Yin-deficiency and Qi-deficiency) may prevent a healthy status developing into SHS or lead to the regression of SHS.

No MeSH data available.


Related in: MedlinePlus