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Detecting microvascular changes in the mouse spleen using optical computed tomography.

McErlean CM, Boult JK, Collins DJ, Leach MO, Robinson SP, Doran SJ - Microvasc. Res. (2015)

Bottom Line: A significant difference in total splenic volume was found between vehicle and ZD6126-treated cohorts, with mean volumes of 61±3mm(3) and 44±3mm(3) respectively (both n=3, p=0.05).Textural statistics for each sample were calculated using grey-level co-occurrence matrices (GLCMs).Standard 2-D GLCM analysis was found to be slice-dependent while 3-D GLCM contrast and homogeneity analysis resulted in separation of the vehicle and ZD6126-treated cohorts over a range of length scales.

View Article: PubMed Central - PubMed

Affiliation: Cancer Research UK Cancer Imaging Centre, The Institute of Cancer Research, Sutton SM2 5NG, UK. Electronic address: cmcerlean@icr.ac.uk.

No MeSH data available.


Related in: MedlinePlus

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Detecting microvascular changes in the mouse spleen using optical computed tomography.

McErlean CM, Boult JK, Collins DJ, Leach MO, Robinson SP, Doran SJ - Microvasc. Res. (2015)

© Copyright Policy - CC BY
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4542549&req=5

Bottom Line: A significant difference in total splenic volume was found between vehicle and ZD6126-treated cohorts, with mean volumes of 61±3mm(3) and 44±3mm(3) respectively (both n=3, p=0.05).Textural statistics for each sample were calculated using grey-level co-occurrence matrices (GLCMs).Standard 2-D GLCM analysis was found to be slice-dependent while 3-D GLCM contrast and homogeneity analysis resulted in separation of the vehicle and ZD6126-treated cohorts over a range of length scales.

View Article: PubMed Central - PubMed

Affiliation: Cancer Research UK Cancer Imaging Centre, The Institute of Cancer Research, Sutton SM2 5NG, UK. Electronic address: cmcerlean@icr.ac.uk.

No MeSH data available.


Related in: MedlinePlus