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Electrochemical Co-Reduction Synthesis of AuPt Bimetallic Nanoparticles-Graphene Nanocomposites for Selective Detection of Dopamine in the Presence of Ascorbic Acid and Uric Acid.

Zhao Z, Zhang M, Chen X, Li Y, Wang J - Sensors (Basel) (2015)

Bottom Line: In this paper, AuPt bimetallic nanoparticles-graphene nanocomposites were obtained by electrochemical co-reduction of graphene oxide (GO), HAuCl4 and H2PtCl6.The linear range of the constructed DA sensor was from 1.6 μM to 39.7 μM with a detection limit of 0.1 μM (S/N = 3).The obtained DA sensor with good stability, high reproducibility and excellent selectivity made it possible to detect DA in human urine samples.

View Article: PubMed Central - PubMed

Affiliation: The Key Laboratory of Biomedical Information Engineering of Ministry of Education, Institute of Biomedical Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China. zhaozongya2010@stu.xjtu.edu.cn.

ABSTRACT
In this paper, AuPt bimetallic nanoparticles-graphene nanocomposites were obtained by electrochemical co-reduction of graphene oxide (GO), HAuCl4 and H2PtCl6. The as-prepared AuPt bimetallic nanoparticles-graphene nanocomposites were characterized by scanning electron microscopy (SEM), electrochemical impedance spectroscopy (EIS) and other electrochemical methods. The morphology and composition of the nanocomposite could be easily controlled by adjusting the HAuCl4/H2PtCl6 concentration ratio. The electrochemical experiments showed that when the concentration ratio of HAuCl4/H2PtCl6 was 1:1, the obtained AuPt bimetallic nanoparticles-graphene nanocomposite (denoted as Au1Pt1NPs-GR) possessed the highest electrocatalytic activity toward dopamine (DA). As such, Au1Pt1NPs-GR nanocomposites were used to detect DA in the presence of ascorbic acid (AA) and uric acid (UA) using the differential pulse voltammetry (DPV) technique and on the modified electrode, there were three separate DPV oxidation peaks with the peak potential separations of 177 mV, 130 mV and 307 mV for DA and AA, DA and UA, AA and UA, respectively. The linear range of the constructed DA sensor was from 1.6 μM to 39.7 μM with a detection limit of 0.1 μM (S/N = 3). The obtained DA sensor with good stability, high reproducibility and excellent selectivity made it possible to detect DA in human urine samples.

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Cyclic voltammograms of (a) Au2Pt1NPs-GR; (b) Au1Pt1NPs-GR and (c) Au1Pt2NPs-GR nanocomposites modified electrodes in 0.5 M H2SO4 at scan rates of 100 mV/s.
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sensors-15-16614-f002: Cyclic voltammograms of (a) Au2Pt1NPs-GR; (b) Au1Pt1NPs-GR and (c) Au1Pt2NPs-GR nanocomposites modified electrodes in 0.5 M H2SO4 at scan rates of 100 mV/s.

Mentions: Figure 2 showed the cyclic voltammetric responses of Au2Pt1NPs-GR/GCE (curve a), Au1Pt1NPs-GR/GCE (curve b) and Au1Pt2NPs-GR/GCE (curve c) in 0.5 M H2SO4. The potential peaks from −200 mV to 100 mV resulted from the hydrogen adsorption/desorption reactions. The reduction peaks at about 400 mV and 900 mV corresponded to the reduction of Au and Pt oxide species, respectively [45]. Particularly, for Au1Pt2NPs-GR/GCE, the near absence of the Au oxide reduction peak showed that Au nanoparticles were covered by Pt and few exposed Au sites still remained. However, Au1Pt1NPs-GR/GCE showed almost the largest reduction peaks of Au and Pt oxide species in H2SO4 solution, which indicated that the modified electrode possessed the highest metal electrochemical catalytic area.


Electrochemical Co-Reduction Synthesis of AuPt Bimetallic Nanoparticles-Graphene Nanocomposites for Selective Detection of Dopamine in the Presence of Ascorbic Acid and Uric Acid.

Zhao Z, Zhang M, Chen X, Li Y, Wang J - Sensors (Basel) (2015)

Cyclic voltammograms of (a) Au2Pt1NPs-GR; (b) Au1Pt1NPs-GR and (c) Au1Pt2NPs-GR nanocomposites modified electrodes in 0.5 M H2SO4 at scan rates of 100 mV/s.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4541896&req=5

sensors-15-16614-f002: Cyclic voltammograms of (a) Au2Pt1NPs-GR; (b) Au1Pt1NPs-GR and (c) Au1Pt2NPs-GR nanocomposites modified electrodes in 0.5 M H2SO4 at scan rates of 100 mV/s.
Mentions: Figure 2 showed the cyclic voltammetric responses of Au2Pt1NPs-GR/GCE (curve a), Au1Pt1NPs-GR/GCE (curve b) and Au1Pt2NPs-GR/GCE (curve c) in 0.5 M H2SO4. The potential peaks from −200 mV to 100 mV resulted from the hydrogen adsorption/desorption reactions. The reduction peaks at about 400 mV and 900 mV corresponded to the reduction of Au and Pt oxide species, respectively [45]. Particularly, for Au1Pt2NPs-GR/GCE, the near absence of the Au oxide reduction peak showed that Au nanoparticles were covered by Pt and few exposed Au sites still remained. However, Au1Pt1NPs-GR/GCE showed almost the largest reduction peaks of Au and Pt oxide species in H2SO4 solution, which indicated that the modified electrode possessed the highest metal electrochemical catalytic area.

Bottom Line: In this paper, AuPt bimetallic nanoparticles-graphene nanocomposites were obtained by electrochemical co-reduction of graphene oxide (GO), HAuCl4 and H2PtCl6.The linear range of the constructed DA sensor was from 1.6 μM to 39.7 μM with a detection limit of 0.1 μM (S/N = 3).The obtained DA sensor with good stability, high reproducibility and excellent selectivity made it possible to detect DA in human urine samples.

View Article: PubMed Central - PubMed

Affiliation: The Key Laboratory of Biomedical Information Engineering of Ministry of Education, Institute of Biomedical Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, China. zhaozongya2010@stu.xjtu.edu.cn.

ABSTRACT
In this paper, AuPt bimetallic nanoparticles-graphene nanocomposites were obtained by electrochemical co-reduction of graphene oxide (GO), HAuCl4 and H2PtCl6. The as-prepared AuPt bimetallic nanoparticles-graphene nanocomposites were characterized by scanning electron microscopy (SEM), electrochemical impedance spectroscopy (EIS) and other electrochemical methods. The morphology and composition of the nanocomposite could be easily controlled by adjusting the HAuCl4/H2PtCl6 concentration ratio. The electrochemical experiments showed that when the concentration ratio of HAuCl4/H2PtCl6 was 1:1, the obtained AuPt bimetallic nanoparticles-graphene nanocomposite (denoted as Au1Pt1NPs-GR) possessed the highest electrocatalytic activity toward dopamine (DA). As such, Au1Pt1NPs-GR nanocomposites were used to detect DA in the presence of ascorbic acid (AA) and uric acid (UA) using the differential pulse voltammetry (DPV) technique and on the modified electrode, there were three separate DPV oxidation peaks with the peak potential separations of 177 mV, 130 mV and 307 mV for DA and AA, DA and UA, AA and UA, respectively. The linear range of the constructed DA sensor was from 1.6 μM to 39.7 μM with a detection limit of 0.1 μM (S/N = 3). The obtained DA sensor with good stability, high reproducibility and excellent selectivity made it possible to detect DA in human urine samples.

Show MeSH
Related in: MedlinePlus