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PET/CT imaging in lung cancer: indications and findings.

Hochhegger B, Alves GR, Irion KL, Fritscher CC, Fritscher LG, Concatto NH, Marchiori E - J Bras Pneumol (2015 May-Jun)

Bottom Line: In addition, the accuracy of PET/CT has been shown to be greater than is that of conventional modalities in some scenarios, making PET/CT a valuable noninvasive method for the investigation of lung cancer.However, the interpretation of PET/CT findings presents numerous pitfalls and potential confounders.Therefore, it is imperative for pulmonologists and radiologists to familiarize themselves with the most relevant indications for and limitations of PET/CT, seeking to protect their patients from unnecessary radiation exposure and inappropriate treatment.

View Article: PubMed Central - PubMed

Affiliation: Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

ABSTRACT
The use of PET/CT imaging in the work-up and management of patients with lung cancer has greatly increased in recent decades. The ability to combine functional and anatomical information has equipped PET/CT to look into various aspects of lung cancer, allowing more precise disease staging and providing useful data during the characterization of indeterminate pulmonary nodules. In addition, the accuracy of PET/CT has been shown to be greater than is that of conventional modalities in some scenarios, making PET/CT a valuable noninvasive method for the investigation of lung cancer. However, the interpretation of PET/CT findings presents numerous pitfalls and potential confounders. Therefore, it is imperative for pulmonologists and radiologists to familiarize themselves with the most relevant indications for and limitations of PET/CT, seeking to protect their patients from unnecessary radiation exposure and inappropriate treatment. This review article aimed to summarize the basic principles, indications, cancer staging considerations, and future applications related to the use of PET/CT in lung cancer.

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Related in: MedlinePlus

Imagens de PET/TC que permitiram o diagn√≥stico de met√°stases √≥sseas (A) e met√°stases adrenais (B) em paciente do sexo masculino, de 79 anos de idade, com c√Ęncer de pulm√£o de c√©lulas n√£o pequenas. Embora essas les√Ķes tenham sido sugeridas pela PET isoladamente (C), n√£o foi poss√≠vel determinar sua exata localiza√ß√£o e delineamento sem a adi√ß√£o da TC.
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f08: Imagens de PET/TC que permitiram o diagn√≥stico de met√°stases √≥sseas (A) e met√°stases adrenais (B) em paciente do sexo masculino, de 79 anos de idade, com c√Ęncer de pulm√£o de c√©lulas n√£o pequenas. Embora essas les√Ķes tenham sido sugeridas pela PET isoladamente (C), n√£o foi poss√≠vel determinar sua exata localiza√ß√£o e delineamento sem a adi√ß√£o da TC.

Mentions: O protocolo do estadiamento M convencional h√° muito inclui imagens de TC de t√≥rax e abdome superior (monitoramento do f√≠gado e gl√Ęndulas adrenais). Quando ocorre doen√ßa IIIA ou IIIB, a cintilografia √≥ssea e a imagiologia cerebral (por TC ou RM) tamb√©m s√£o tipicamente realizadas a fim de investigar les√Ķes √≥sseas e do sistema nervoso central (SNC), respectivamente.(3) Por√©m, a PET/TC recentemente mostrou grande utilidade no estadiamento M de pacientes com CPCNP (Figura 3), particularmente naqueles com manifesta√ß√Ķes cl√≠nicas da doen√ßa. Al√©m disso, a PET/TC √© capaz de proporcionar informa√ß√Ķes mais pertinentes durante a avalia√ß√£o pr√©-operat√≥ria do que a TC isoladamente, com a exce√ß√£o da avalia√ß√£o de met√°stases cerebrais, para as quais as duas modalidades produzem resultados semelhantes e t√™m limita√ß√Ķes semelhantes.(12)


PET/CT imaging in lung cancer: indications and findings.

Hochhegger B, Alves GR, Irion KL, Fritscher CC, Fritscher LG, Concatto NH, Marchiori E - J Bras Pneumol (2015 May-Jun)

Imagens de PET/TC que permitiram o diagn√≥stico de met√°stases √≥sseas (A) e met√°stases adrenais (B) em paciente do sexo masculino, de 79 anos de idade, com c√Ęncer de pulm√£o de c√©lulas n√£o pequenas. Embora essas les√Ķes tenham sido sugeridas pela PET isoladamente (C), n√£o foi poss√≠vel determinar sua exata localiza√ß√£o e delineamento sem a adi√ß√£o da TC.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4541763&req=5

f08: Imagens de PET/TC que permitiram o diagn√≥stico de met√°stases √≥sseas (A) e met√°stases adrenais (B) em paciente do sexo masculino, de 79 anos de idade, com c√Ęncer de pulm√£o de c√©lulas n√£o pequenas. Embora essas les√Ķes tenham sido sugeridas pela PET isoladamente (C), n√£o foi poss√≠vel determinar sua exata localiza√ß√£o e delineamento sem a adi√ß√£o da TC.
Mentions: O protocolo do estadiamento M convencional h√° muito inclui imagens de TC de t√≥rax e abdome superior (monitoramento do f√≠gado e gl√Ęndulas adrenais). Quando ocorre doen√ßa IIIA ou IIIB, a cintilografia √≥ssea e a imagiologia cerebral (por TC ou RM) tamb√©m s√£o tipicamente realizadas a fim de investigar les√Ķes √≥sseas e do sistema nervoso central (SNC), respectivamente.(3) Por√©m, a PET/TC recentemente mostrou grande utilidade no estadiamento M de pacientes com CPCNP (Figura 3), particularmente naqueles com manifesta√ß√Ķes cl√≠nicas da doen√ßa. Al√©m disso, a PET/TC √© capaz de proporcionar informa√ß√Ķes mais pertinentes durante a avalia√ß√£o pr√©-operat√≥ria do que a TC isoladamente, com a exce√ß√£o da avalia√ß√£o de met√°stases cerebrais, para as quais as duas modalidades produzem resultados semelhantes e t√™m limita√ß√Ķes semelhantes.(12)

Bottom Line: In addition, the accuracy of PET/CT has been shown to be greater than is that of conventional modalities in some scenarios, making PET/CT a valuable noninvasive method for the investigation of lung cancer.However, the interpretation of PET/CT findings presents numerous pitfalls and potential confounders.Therefore, it is imperative for pulmonologists and radiologists to familiarize themselves with the most relevant indications for and limitations of PET/CT, seeking to protect their patients from unnecessary radiation exposure and inappropriate treatment.

View Article: PubMed Central - PubMed

Affiliation: Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

ABSTRACT
The use of PET/CT imaging in the work-up and management of patients with lung cancer has greatly increased in recent decades. The ability to combine functional and anatomical information has equipped PET/CT to look into various aspects of lung cancer, allowing more precise disease staging and providing useful data during the characterization of indeterminate pulmonary nodules. In addition, the accuracy of PET/CT has been shown to be greater than is that of conventional modalities in some scenarios, making PET/CT a valuable noninvasive method for the investigation of lung cancer. However, the interpretation of PET/CT findings presents numerous pitfalls and potential confounders. Therefore, it is imperative for pulmonologists and radiologists to familiarize themselves with the most relevant indications for and limitations of PET/CT, seeking to protect their patients from unnecessary radiation exposure and inappropriate treatment. This review article aimed to summarize the basic principles, indications, cancer staging considerations, and future applications related to the use of PET/CT in lung cancer.

Show MeSH
Related in: MedlinePlus