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Small interstitial nodules.

Marchiori E, Zanetti G, Hochhegger B - J Bras Pneumol (2015 May-Jun)

View Article: PubMed Central - PubMed

Affiliation: Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

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A 45-year-old male patient presented to our outpatient clinic with a three-week history of low-grade fever, mildly productive cough, headache, and asthenia... On the basis of their distribution throughout the lung parenchyma, they can be classified as perilymphatic, centrilobular, or random... Perilymphatic nodules are small nodules located predominantly in the peribronchovascular interstitium, interlobular septa, and subpleural regions (which contain the pulmonary lymphatic system)... They are commonly found in cases of sarcoidosis, silicosis, and lymphangitic carcinomatosis... A centrilobular distribution is characterized by nodules that are located within a few millimeters of the pleural surface and fissures but do not touch them... Centrilobular nodules can be found in cases of hypersensitivity pneumonitis, silicosis, and infectious bronchiolitis, for example... This distribution pattern is consistent with miliary tuberculosis, histoplasmosis, and hematogenous metastasis... Metastatic nodules tend to predominate in the lower lung fields, whereas, in miliary tuberculosis, they tend to predominate in the upper lung fields... In addition, nodules commonly vary in size in cases of metastasis, whereas, in cases of miliary infection, they do not tend to... Our patient tested positive for HIV, his CD4 count was 140 cells/µL, and radial immunodiffusion was positive for histoplasmosis... In the case reported here, a final diagnosis of histoplasmosis was established on the basis of the clinical picture, the epidemiological history, serology results, and CT findings.

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Pequenos nódulos distribuídos homogeneamente pelos pulmões, sem predominar em nenhum compartimento específico. Observar que alguns deles tocam a superfície pleural e que outros se encontram em contato com as cissuras.
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f02: Pequenos nódulos distribuídos homogeneamente pelos pulmões, sem predominar em nenhum compartimento específico. Observar que alguns deles tocam a superfície pleural e que outros se encontram em contato com as cissuras.

Mentions: Homem, 45 anos, procurou o ambulatório com queixas de febre baixa, tosse pouco produtiva, cefaleia e astenia há três semanas, assim como emagrecimento de 5 kg nos últimos quatro meses. O paciente relatara ter um irmão com diagnóstico de tuberculose pulmonar há dois meses em tratamento, assim como costumar passar finais de semana em um sítio em zona rural. A TCAR mostrou pequenos nódulos disseminados (Figura 1).


Small interstitial nodules.

Marchiori E, Zanetti G, Hochhegger B - J Bras Pneumol (2015 May-Jun)

Pequenos nódulos distribuídos homogeneamente pelos pulmões, sem predominar em nenhum compartimento específico. Observar que alguns deles tocam a superfície pleural e que outros se encontram em contato com as cissuras.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4541761&req=5

f02: Pequenos nódulos distribuídos homogeneamente pelos pulmões, sem predominar em nenhum compartimento específico. Observar que alguns deles tocam a superfície pleural e que outros se encontram em contato com as cissuras.
Mentions: Homem, 45 anos, procurou o ambulatório com queixas de febre baixa, tosse pouco produtiva, cefaleia e astenia há três semanas, assim como emagrecimento de 5 kg nos últimos quatro meses. O paciente relatara ter um irmão com diagnóstico de tuberculose pulmonar há dois meses em tratamento, assim como costumar passar finais de semana em um sítio em zona rural. A TCAR mostrou pequenos nódulos disseminados (Figura 1).

View Article: PubMed Central - PubMed

Affiliation: Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

A 45-year-old male patient presented to our outpatient clinic with a three-week history of low-grade fever, mildly productive cough, headache, and asthenia... On the basis of their distribution throughout the lung parenchyma, they can be classified as perilymphatic, centrilobular, or random... Perilymphatic nodules are small nodules located predominantly in the peribronchovascular interstitium, interlobular septa, and subpleural regions (which contain the pulmonary lymphatic system)... They are commonly found in cases of sarcoidosis, silicosis, and lymphangitic carcinomatosis... A centrilobular distribution is characterized by nodules that are located within a few millimeters of the pleural surface and fissures but do not touch them... Centrilobular nodules can be found in cases of hypersensitivity pneumonitis, silicosis, and infectious bronchiolitis, for example... This distribution pattern is consistent with miliary tuberculosis, histoplasmosis, and hematogenous metastasis... Metastatic nodules tend to predominate in the lower lung fields, whereas, in miliary tuberculosis, they tend to predominate in the upper lung fields... In addition, nodules commonly vary in size in cases of metastasis, whereas, in cases of miliary infection, they do not tend to... Our patient tested positive for HIV, his CD4 count was 140 cells/µL, and radial immunodiffusion was positive for histoplasmosis... In the case reported here, a final diagnosis of histoplasmosis was established on the basis of the clinical picture, the epidemiological history, serology results, and CT findings.

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