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Small interstitial nodules.

Marchiori E, Zanetti G, Hochhegger B - J Bras Pneumol (2015 May-Jun)

View Article: PubMed Central - PubMed

Affiliation: Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

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A 45-year-old male patient presented to our outpatient clinic with a three-week history of low-grade fever, mildly productive cough, headache, and asthenia... On the basis of their distribution throughout the lung parenchyma, they can be classified as perilymphatic, centrilobular, or random... Perilymphatic nodules are small nodules located predominantly in the peribronchovascular interstitium, interlobular septa, and subpleural regions (which contain the pulmonary lymphatic system)... They are commonly found in cases of sarcoidosis, silicosis, and lymphangitic carcinomatosis... A centrilobular distribution is characterized by nodules that are located within a few millimeters of the pleural surface and fissures but do not touch them... Centrilobular nodules can be found in cases of hypersensitivity pneumonitis, silicosis, and infectious bronchiolitis, for example... This distribution pattern is consistent with miliary tuberculosis, histoplasmosis, and hematogenous metastasis... Metastatic nodules tend to predominate in the lower lung fields, whereas, in miliary tuberculosis, they tend to predominate in the upper lung fields... In addition, nodules commonly vary in size in cases of metastasis, whereas, in cases of miliary infection, they do not tend to... Our patient tested positive for HIV, his CD4 count was 140 cells/µL, and radial immunodiffusion was positive for histoplasmosis... In the case reported here, a final diagnosis of histoplasmosis was established on the basis of the clinical picture, the epidemiological history, serology results, and CT findings.

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Small nodules evenly distributed throughout the lungs, no particular lung compartment being predominantly affected. Note that some of the nodules touch the pleural surface, whereas others are in contact with the fissures.
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f01: Small nodules evenly distributed throughout the lungs, no particular lung compartment being predominantly affected. Note that some of the nodules touch the pleural surface, whereas others are in contact with the fissures.

Mentions: A 45-year-old male patient presented to our outpatient clinic with a three-week history of low-grade fever, mildly productive cough, headache, and asthenia. He had lost 5 kg in the last four months. The patient reported that he had a brother who had been diagnosed with pulmonary tuberculosis and had been receiving treatment for it for two months. He also reported that he habitually spent his weekends on a grange in a rural area. A HRCT scan of the chest showed small disseminated nodules (Figure 1).


Small interstitial nodules.

Marchiori E, Zanetti G, Hochhegger B - J Bras Pneumol (2015 May-Jun)

Small nodules evenly distributed throughout the lungs, no particular lung compartment being predominantly affected. Note that some of the nodules touch the pleural surface, whereas others are in contact with the fissures.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4541761&req=5

f01: Small nodules evenly distributed throughout the lungs, no particular lung compartment being predominantly affected. Note that some of the nodules touch the pleural surface, whereas others are in contact with the fissures.
Mentions: A 45-year-old male patient presented to our outpatient clinic with a three-week history of low-grade fever, mildly productive cough, headache, and asthenia. He had lost 5 kg in the last four months. The patient reported that he had a brother who had been diagnosed with pulmonary tuberculosis and had been receiving treatment for it for two months. He also reported that he habitually spent his weekends on a grange in a rural area. A HRCT scan of the chest showed small disseminated nodules (Figure 1).

View Article: PubMed Central - PubMed

Affiliation: Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

AUTOMATICALLY GENERATED EXCERPT
Please rate it.

A 45-year-old male patient presented to our outpatient clinic with a three-week history of low-grade fever, mildly productive cough, headache, and asthenia... On the basis of their distribution throughout the lung parenchyma, they can be classified as perilymphatic, centrilobular, or random... Perilymphatic nodules are small nodules located predominantly in the peribronchovascular interstitium, interlobular septa, and subpleural regions (which contain the pulmonary lymphatic system)... They are commonly found in cases of sarcoidosis, silicosis, and lymphangitic carcinomatosis... A centrilobular distribution is characterized by nodules that are located within a few millimeters of the pleural surface and fissures but do not touch them... Centrilobular nodules can be found in cases of hypersensitivity pneumonitis, silicosis, and infectious bronchiolitis, for example... This distribution pattern is consistent with miliary tuberculosis, histoplasmosis, and hematogenous metastasis... Metastatic nodules tend to predominate in the lower lung fields, whereas, in miliary tuberculosis, they tend to predominate in the upper lung fields... In addition, nodules commonly vary in size in cases of metastasis, whereas, in cases of miliary infection, they do not tend to... Our patient tested positive for HIV, his CD4 count was 140 cells/µL, and radial immunodiffusion was positive for histoplasmosis... In the case reported here, a final diagnosis of histoplasmosis was established on the basis of the clinical picture, the epidemiological history, serology results, and CT findings.

Show MeSH