Limits...
Tongguan capsule ameliorates coronary artery stenosis in a 40-year-old woman.

Ma H, Wang L, Huang D, Liu G, Zhang M - Drug Des Devel Ther (2015)

Bottom Line: Cardiovascular disease is the leading cause of death worldwide, with coronary heart disease as the major contributor to this related mortality.In this case report, we describe the therapeutic effects of Tongguan capsule in a 40-year-old woman diagnosed with stable angina pectoris.To the best of the authors' knowledge, this is the first case documented of the therapeutic effect of Tongguan capsule in the treatment of coronary heart disease.

View Article: PubMed Central - PubMed

Affiliation: Department of Critical Care Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangdong, People's Republic of China.

ABSTRACT
Cardiovascular disease is the leading cause of death worldwide, with coronary heart disease as the major contributor to this related mortality. There is a growing trend in the application of Chinese medicine in clinical practice for the treatment of coronary heart disease. However, there is a lack of knowledge surrounding the pharmacological, toxicological, and biological profiles of Chinese medicine. In this case report, we describe the therapeutic effects of Tongguan capsule in a 40-year-old woman diagnosed with stable angina pectoris. To the best of the authors' knowledge, this is the first case documented of the therapeutic effect of Tongguan capsule in the treatment of coronary heart disease.

No MeSH data available.


Related in: MedlinePlus

The coronary CT angiography of the patient.Notes: Panels (A and B) show the first diagonal branch of the left coronary artery with approximately 50% stenosis, and the atherosclerotic plaque which was non-calcified prior to the treatment. Panels (C and D) show that the plaque in the first diagonal branch of left coronary artery disappeared after a 10-month Tongguan capsule treatment. The arrow in Figure I A indicates the stenosis. The arrow in Figure I C indicates the stenosis has disappeared.
© Copyright Policy
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4539080&req=5

f1-dddt-9-4413: The coronary CT angiography of the patient.Notes: Panels (A and B) show the first diagonal branch of the left coronary artery with approximately 50% stenosis, and the atherosclerotic plaque which was non-calcified prior to the treatment. Panels (C and D) show that the plaque in the first diagonal branch of left coronary artery disappeared after a 10-month Tongguan capsule treatment. The arrow in Figure I A indicates the stenosis. The arrow in Figure I C indicates the stenosis has disappeared.

Mentions: In October 2013, a 40-year-old woman sought medical advice from Guangdong Provincial Hospital of Chinese Medicine with a complaint of atypical chest pain, which had been ongoing for 1 month. She had no diabetes, hypertension, or obesity, was a nonsmoker, and had no family history of CVD. On arrival, her blood pressure was 122/73 mmHg, and heart rate was 71 beats per minute. The laboratory examination on admission showed that her low-density lipoprotein cholesterol (LDL-C) level was 2.1 mmol/L, and non-high-density lipoprotein cholesterol (non-HDL-C) level was 2.89 mmol/L. The 24-hour electrocardiogram results showed a sinus rhythm and ST-T segment depression when the heart beats >120 bpm. Ultracardiography results showed a normal cardiac function with the ejection fraction at 72% and mild tricuspid regurgitation. The coronary computed tomography (CT) scan demonstrated that the first diagonal branch of the left coronary artery was approximately 50% stenosis, and the atherosclerotic plaque was non-calcified (Figure 1A and B).


Tongguan capsule ameliorates coronary artery stenosis in a 40-year-old woman.

Ma H, Wang L, Huang D, Liu G, Zhang M - Drug Des Devel Ther (2015)

The coronary CT angiography of the patient.Notes: Panels (A and B) show the first diagonal branch of the left coronary artery with approximately 50% stenosis, and the atherosclerotic plaque which was non-calcified prior to the treatment. Panels (C and D) show that the plaque in the first diagonal branch of left coronary artery disappeared after a 10-month Tongguan capsule treatment. The arrow in Figure I A indicates the stenosis. The arrow in Figure I C indicates the stenosis has disappeared.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4539080&req=5

f1-dddt-9-4413: The coronary CT angiography of the patient.Notes: Panels (A and B) show the first diagonal branch of the left coronary artery with approximately 50% stenosis, and the atherosclerotic plaque which was non-calcified prior to the treatment. Panels (C and D) show that the plaque in the first diagonal branch of left coronary artery disappeared after a 10-month Tongguan capsule treatment. The arrow in Figure I A indicates the stenosis. The arrow in Figure I C indicates the stenosis has disappeared.
Mentions: In October 2013, a 40-year-old woman sought medical advice from Guangdong Provincial Hospital of Chinese Medicine with a complaint of atypical chest pain, which had been ongoing for 1 month. She had no diabetes, hypertension, or obesity, was a nonsmoker, and had no family history of CVD. On arrival, her blood pressure was 122/73 mmHg, and heart rate was 71 beats per minute. The laboratory examination on admission showed that her low-density lipoprotein cholesterol (LDL-C) level was 2.1 mmol/L, and non-high-density lipoprotein cholesterol (non-HDL-C) level was 2.89 mmol/L. The 24-hour electrocardiogram results showed a sinus rhythm and ST-T segment depression when the heart beats >120 bpm. Ultracardiography results showed a normal cardiac function with the ejection fraction at 72% and mild tricuspid regurgitation. The coronary computed tomography (CT) scan demonstrated that the first diagonal branch of the left coronary artery was approximately 50% stenosis, and the atherosclerotic plaque was non-calcified (Figure 1A and B).

Bottom Line: Cardiovascular disease is the leading cause of death worldwide, with coronary heart disease as the major contributor to this related mortality.In this case report, we describe the therapeutic effects of Tongguan capsule in a 40-year-old woman diagnosed with stable angina pectoris.To the best of the authors' knowledge, this is the first case documented of the therapeutic effect of Tongguan capsule in the treatment of coronary heart disease.

View Article: PubMed Central - PubMed

Affiliation: Department of Critical Care Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangdong, People's Republic of China.

ABSTRACT
Cardiovascular disease is the leading cause of death worldwide, with coronary heart disease as the major contributor to this related mortality. There is a growing trend in the application of Chinese medicine in clinical practice for the treatment of coronary heart disease. However, there is a lack of knowledge surrounding the pharmacological, toxicological, and biological profiles of Chinese medicine. In this case report, we describe the therapeutic effects of Tongguan capsule in a 40-year-old woman diagnosed with stable angina pectoris. To the best of the authors' knowledge, this is the first case documented of the therapeutic effect of Tongguan capsule in the treatment of coronary heart disease.

No MeSH data available.


Related in: MedlinePlus