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Sleep Quality Improves During Treatment With Bryophyllum pinnatum: An Observational Study on Cancer Patients.

Simões-Wüst AP, Hassani TA, Müller-Hübenthal B, Pittl S, Kuck A, Meden H, Eberhard J, Decker M, Fürer K, von Mandach U, Bryophyllum Collaborative Gro - Integr Cancer Ther (2015)

Bottom Line: Bryophyllum pinnatum is a herbal medication used in anthroposophic medicine, which has been shown to be associated with improvements in sleep quality during pregnancy with only few and minor or moderate side-effects reported.During treatment with B pinnatum, the PSQI decreased from 12.2 ± 3.62 to 9.1 ± 3.61 (P < .01), and ESS changed from 8.4 ± 3.18 to 7.1 ± 3.98 (P < .05).The treatment was well tolerated by the majority of patients, with only 6 patients reporting discomfort that might have been caused by B pinnatum (fatigue n = 3, dry throat n = 1, agitation n = 1, difficult digestion n = 1).

View Article: PubMed Central - PubMed

Affiliation: Paracelsus-Hospital Richterswil, Richterswil, Switzerland Clinic Arlesheim, Arlesheim, Switzerland anapaula.simoes-wuest@klinik-arlesheim.ch.

No MeSH data available.


Related in: MedlinePlus

Most components of the Pittsburgh Sleep Quality Index improved during treatment of cancer patients with B pinnatum for 3 weeks.
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fig2-1534735415580680: Most components of the Pittsburgh Sleep Quality Index improved during treatment of cancer patients with B pinnatum for 3 weeks.

Mentions: During treatment with B pinnatum, sleep quality of the participating cancer patients improved markedly, inasmuch as a statistically significant reduction of PSQI was observed (from 12.2 ± 3.62 down to 9.1 ± 3.61, P = .002; Figure 1). It should be kept in mind that the higher the values of the global PSQI (and of the corresponding components), the worse the sleep quality. The number of patients below the cutoff for poor sleepers (ie, PSQI >5) increased from 1 at study beginning (PSQI = 5) to 3 (PSQI values of 4, 3, and 3). When the different PSQI components were compared at the beginning and at the end of the treatment (Figure 2), improvements of subjective sleep quality (1.7 ± 0.67 vs 1.1 ± 0.79, P = .008), sleep latency (2.6 ± 0.71 vs 2.1 ± 0.75, P = .024), habitual sleep efficiency (1.9 ± 1.02 vs 1.4 ± 1.04, P = .045), sleep disturbance (1.7 ± 0.59 vs 1.4 ± 0.59, P = .014), and a reduction in the use of sleeping medication (1.3 ± 1.41 vs 0.45 ± 1.10, P = .035) were detected. A tendency for an improvement was observed in the case of sleep duration (1.9 ± 1.09 vs 1.35 ± 1.19, P = .160). No significant alteration was detected in daytime dysfunction (1.4 ± 0.75 vs 1.5 ± 0.76, P = .739).


Sleep Quality Improves During Treatment With Bryophyllum pinnatum: An Observational Study on Cancer Patients.

Simões-Wüst AP, Hassani TA, Müller-Hübenthal B, Pittl S, Kuck A, Meden H, Eberhard J, Decker M, Fürer K, von Mandach U, Bryophyllum Collaborative Gro - Integr Cancer Ther (2015)

Most components of the Pittsburgh Sleep Quality Index improved during treatment of cancer patients with B pinnatum for 3 weeks.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2 - License 3
Show All Figures
getmorefigures.php?uid=PMC4538317&req=5

fig2-1534735415580680: Most components of the Pittsburgh Sleep Quality Index improved during treatment of cancer patients with B pinnatum for 3 weeks.
Mentions: During treatment with B pinnatum, sleep quality of the participating cancer patients improved markedly, inasmuch as a statistically significant reduction of PSQI was observed (from 12.2 ± 3.62 down to 9.1 ± 3.61, P = .002; Figure 1). It should be kept in mind that the higher the values of the global PSQI (and of the corresponding components), the worse the sleep quality. The number of patients below the cutoff for poor sleepers (ie, PSQI >5) increased from 1 at study beginning (PSQI = 5) to 3 (PSQI values of 4, 3, and 3). When the different PSQI components were compared at the beginning and at the end of the treatment (Figure 2), improvements of subjective sleep quality (1.7 ± 0.67 vs 1.1 ± 0.79, P = .008), sleep latency (2.6 ± 0.71 vs 2.1 ± 0.75, P = .024), habitual sleep efficiency (1.9 ± 1.02 vs 1.4 ± 1.04, P = .045), sleep disturbance (1.7 ± 0.59 vs 1.4 ± 0.59, P = .014), and a reduction in the use of sleeping medication (1.3 ± 1.41 vs 0.45 ± 1.10, P = .035) were detected. A tendency for an improvement was observed in the case of sleep duration (1.9 ± 1.09 vs 1.35 ± 1.19, P = .160). No significant alteration was detected in daytime dysfunction (1.4 ± 0.75 vs 1.5 ± 0.76, P = .739).

Bottom Line: Bryophyllum pinnatum is a herbal medication used in anthroposophic medicine, which has been shown to be associated with improvements in sleep quality during pregnancy with only few and minor or moderate side-effects reported.During treatment with B pinnatum, the PSQI decreased from 12.2 ± 3.62 to 9.1 ± 3.61 (P < .01), and ESS changed from 8.4 ± 3.18 to 7.1 ± 3.98 (P < .05).The treatment was well tolerated by the majority of patients, with only 6 patients reporting discomfort that might have been caused by B pinnatum (fatigue n = 3, dry throat n = 1, agitation n = 1, difficult digestion n = 1).

View Article: PubMed Central - PubMed

Affiliation: Paracelsus-Hospital Richterswil, Richterswil, Switzerland Clinic Arlesheim, Arlesheim, Switzerland anapaula.simoes-wuest@klinik-arlesheim.ch.

No MeSH data available.


Related in: MedlinePlus