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Sleep Quality Improves During Treatment With Bryophyllum pinnatum: An Observational Study on Cancer Patients.

Simões-Wüst AP, Hassani TA, Müller-Hübenthal B, Pittl S, Kuck A, Meden H, Eberhard J, Decker M, Fürer K, von Mandach U, Bryophyllum Collaborative Gro - Integr Cancer Ther (2015)

Bottom Line: Bryophyllum pinnatum is a herbal medication used in anthroposophic medicine, which has been shown to be associated with improvements in sleep quality during pregnancy with only few and minor or moderate side-effects reported.During treatment with B pinnatum, the PSQI decreased from 12.2 ± 3.62 to 9.1 ± 3.61 (P < .01), and ESS changed from 8.4 ± 3.18 to 7.1 ± 3.98 (P < .05).The treatment was well tolerated by the majority of patients, with only 6 patients reporting discomfort that might have been caused by B pinnatum (fatigue n = 3, dry throat n = 1, agitation n = 1, difficult digestion n = 1).

View Article: PubMed Central - PubMed

Affiliation: Paracelsus-Hospital Richterswil, Richterswil, Switzerland Clinic Arlesheim, Arlesheim, Switzerland anapaula.simoes-wuest@klinik-arlesheim.ch.

No MeSH data available.


Related in: MedlinePlus

Improvement in sleep quality of cancer patients as assessed by the Pittsburgh Sleep Quality Index (PSGI; P = .002) during treatment with B pinnatum for 3 weeks.
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fig1-1534735415580680: Improvement in sleep quality of cancer patients as assessed by the Pittsburgh Sleep Quality Index (PSGI; P = .002) during treatment with B pinnatum for 3 weeks.

Mentions: The main demographic characteristics and disease characteristics of these patients are depicted in Table 1. The mean patient age was 61 years. The majority lived with a partner, were of female gender, were postmenopausal, exhibited a normal body mass index, had additional diseases (other than cancer), and were taking other medications. All patients complained of sleep disorders or changes in sleep behavior (one of the inclusion criteria), which were mostly long-lasting (2 years on average, median 1 year). The severity of their sleep problems translated into relatively high PSQI values at study beginning (12 ± 3.6 in a 0 to 21 scale; Figure 1; see Discussion) that in all but one case (5; ie, borderline) were above the cutoff value used to define poor sleepers (>5). Concerning the malignant disease, most patients were suffering from breast cancer, were in remission, and had a favorable ECOG performance status. The cancer disease had been diagnosed on average 5 ± 6.2 years previously (median 2 years). Most patients had undergone several cancer-related therapies in the past (more than 1 month before the study); in the month prior to the study as well as during the study, mistletoe therapy was the most frequently mentioned therapy.


Sleep Quality Improves During Treatment With Bryophyllum pinnatum: An Observational Study on Cancer Patients.

Simões-Wüst AP, Hassani TA, Müller-Hübenthal B, Pittl S, Kuck A, Meden H, Eberhard J, Decker M, Fürer K, von Mandach U, Bryophyllum Collaborative Gro - Integr Cancer Ther (2015)

Improvement in sleep quality of cancer patients as assessed by the Pittsburgh Sleep Quality Index (PSGI; P = .002) during treatment with B pinnatum for 3 weeks.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2 - License 3
Show All Figures
getmorefigures.php?uid=PMC4538317&req=5

fig1-1534735415580680: Improvement in sleep quality of cancer patients as assessed by the Pittsburgh Sleep Quality Index (PSGI; P = .002) during treatment with B pinnatum for 3 weeks.
Mentions: The main demographic characteristics and disease characteristics of these patients are depicted in Table 1. The mean patient age was 61 years. The majority lived with a partner, were of female gender, were postmenopausal, exhibited a normal body mass index, had additional diseases (other than cancer), and were taking other medications. All patients complained of sleep disorders or changes in sleep behavior (one of the inclusion criteria), which were mostly long-lasting (2 years on average, median 1 year). The severity of their sleep problems translated into relatively high PSQI values at study beginning (12 ± 3.6 in a 0 to 21 scale; Figure 1; see Discussion) that in all but one case (5; ie, borderline) were above the cutoff value used to define poor sleepers (>5). Concerning the malignant disease, most patients were suffering from breast cancer, were in remission, and had a favorable ECOG performance status. The cancer disease had been diagnosed on average 5 ± 6.2 years previously (median 2 years). Most patients had undergone several cancer-related therapies in the past (more than 1 month before the study); in the month prior to the study as well as during the study, mistletoe therapy was the most frequently mentioned therapy.

Bottom Line: Bryophyllum pinnatum is a herbal medication used in anthroposophic medicine, which has been shown to be associated with improvements in sleep quality during pregnancy with only few and minor or moderate side-effects reported.During treatment with B pinnatum, the PSQI decreased from 12.2 ± 3.62 to 9.1 ± 3.61 (P < .01), and ESS changed from 8.4 ± 3.18 to 7.1 ± 3.98 (P < .05).The treatment was well tolerated by the majority of patients, with only 6 patients reporting discomfort that might have been caused by B pinnatum (fatigue n = 3, dry throat n = 1, agitation n = 1, difficult digestion n = 1).

View Article: PubMed Central - PubMed

Affiliation: Paracelsus-Hospital Richterswil, Richterswil, Switzerland Clinic Arlesheim, Arlesheim, Switzerland anapaula.simoes-wuest@klinik-arlesheim.ch.

No MeSH data available.


Related in: MedlinePlus