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Glycated haemoglobin A1c is associated with low-grade albuminuria in Chinese adults.

Huang X, Zhou Y, Xu B, Sun W, Lin L, Sun J, Xu M, Lu J, Bi Y, Wang W, Xu Y, Ning G - BMJ Open (2015)

Bottom Line: This was a cross-sectional study involving 9188 participants aged 40 years or older.All participants underwent a standard 75 g oral glucose tolerance test.Low-grade albuminuria was defined as the highest quartile of urinary albumin-to-creatinine ratio (ACR) (>6.10 mg/g in males and >8.76 mg/g in females) in respondents without microalbuminuria or macroalbuminuria.

View Article: PubMed Central - PubMed

Affiliation: Key Laboratory for Endocrine and Metabolic Diseases of Ministry of Health, Rui-Jin Hospital, Shanghai Jiao-Tong University School of Medicine, E-Institute of Shanghai Universities, Shanghai, China Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Department of Endocrine and Metabolic Diseases, Rui-Jin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.

No MeSH data available.


Related in: MedlinePlus

Prevalence of low-grade albuminuria according to different glycated haemoglobin A1c (HbA1c) levels. p Values were calculated using the χ2 test.
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BMJOPEN2014007429F1: Prevalence of low-grade albuminuria according to different glycated haemoglobin A1c (HbA1c) levels. p Values were calculated using the χ2 test.

Mentions: Urinary ACR increased significantly with increasing HbA1c levels (pfor trend <0.0001; table 1). Likewise, a significant increase in the prevalence of low-grade albuminuria was observed according to different HbA1c levels (21.3%, 23.9%, 29.2%, 35.6% and 47.5% in HbA1c categories of ≤37 mmol/mol (5.5%), 38–42 mmol/mol (5.6–6.0%), 43–48 mmol/mol (6.1–6.5%), 49–53 mmol/mol (6.6–7.0%) and >53 mmol/mol (7.0%), respectively; pfor trend <0.0001, figure 1).


Glycated haemoglobin A1c is associated with low-grade albuminuria in Chinese adults.

Huang X, Zhou Y, Xu B, Sun W, Lin L, Sun J, Xu M, Lu J, Bi Y, Wang W, Xu Y, Ning G - BMJ Open (2015)

Prevalence of low-grade albuminuria according to different glycated haemoglobin A1c (HbA1c) levels. p Values were calculated using the χ2 test.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4538277&req=5

BMJOPEN2014007429F1: Prevalence of low-grade albuminuria according to different glycated haemoglobin A1c (HbA1c) levels. p Values were calculated using the χ2 test.
Mentions: Urinary ACR increased significantly with increasing HbA1c levels (pfor trend <0.0001; table 1). Likewise, a significant increase in the prevalence of low-grade albuminuria was observed according to different HbA1c levels (21.3%, 23.9%, 29.2%, 35.6% and 47.5% in HbA1c categories of ≤37 mmol/mol (5.5%), 38–42 mmol/mol (5.6–6.0%), 43–48 mmol/mol (6.1–6.5%), 49–53 mmol/mol (6.6–7.0%) and >53 mmol/mol (7.0%), respectively; pfor trend <0.0001, figure 1).

Bottom Line: This was a cross-sectional study involving 9188 participants aged 40 years or older.All participants underwent a standard 75 g oral glucose tolerance test.Low-grade albuminuria was defined as the highest quartile of urinary albumin-to-creatinine ratio (ACR) (>6.10 mg/g in males and >8.76 mg/g in females) in respondents without microalbuminuria or macroalbuminuria.

View Article: PubMed Central - PubMed

Affiliation: Key Laboratory for Endocrine and Metabolic Diseases of Ministry of Health, Rui-Jin Hospital, Shanghai Jiao-Tong University School of Medicine, E-Institute of Shanghai Universities, Shanghai, China Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Department of Endocrine and Metabolic Diseases, Rui-Jin Hospital, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.

No MeSH data available.


Related in: MedlinePlus