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Behavioural physical activity interventions in participants with lower-limb osteoarthritis: a systematic review with meta-analysis.

Williamson W, Kluzek S, Roberts N, Richards J, Arden N, Leeson P, Newton J, Foster C - BMJ Open (2015)

Bottom Line: Subgroup analysis of 6-12 month outcome reduced heterogeneity and increased intervention effect compared to control (SMD 0.53, 95% CI 0.41 to 0.65, z=8.84 (p<0.00001) I(2) of 66%).Effectiveness of intervention declines with extended follow-up beyond 12 months with no significant benefit compared to control.The small number of studies (11 RCTs) limited ability to define effective delivery methods.

View Article: PubMed Central - PubMed

Affiliation: Division of Cardiovascular Medicine, Cardiovascular Clinical Research Facility, University of Oxford, Oxford, UK.

No MeSH data available.


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Forest plot for meta-analysis of self-reported physical activity outcomes following exercise intervention.
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BMJOPEN2015007642F2: Forest plot for meta-analysis of self-reported physical activity outcomes following exercise intervention.

Mentions: Seven studies reported physical activity outcomes using self-report measures, each study using a different measure. Five of the studies reported a positive effect, however only two studies reported a significant difference comparing intervention with control. The pooled effect for the seven interventions was not significant and there was considerable heterogeneity between the interventions (SMD 0.22 with 95% CI −0.11 to 0.56, z=1.3 (p=0.19) I2 statistic of 85%; figure 2).


Behavioural physical activity interventions in participants with lower-limb osteoarthritis: a systematic review with meta-analysis.

Williamson W, Kluzek S, Roberts N, Richards J, Arden N, Leeson P, Newton J, Foster C - BMJ Open (2015)

Forest plot for meta-analysis of self-reported physical activity outcomes following exercise intervention.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4538274&req=5

BMJOPEN2015007642F2: Forest plot for meta-analysis of self-reported physical activity outcomes following exercise intervention.
Mentions: Seven studies reported physical activity outcomes using self-report measures, each study using a different measure. Five of the studies reported a positive effect, however only two studies reported a significant difference comparing intervention with control. The pooled effect for the seven interventions was not significant and there was considerable heterogeneity between the interventions (SMD 0.22 with 95% CI −0.11 to 0.56, z=1.3 (p=0.19) I2 statistic of 85%; figure 2).

Bottom Line: Subgroup analysis of 6-12 month outcome reduced heterogeneity and increased intervention effect compared to control (SMD 0.53, 95% CI 0.41 to 0.65, z=8.84 (p<0.00001) I(2) of 66%).Effectiveness of intervention declines with extended follow-up beyond 12 months with no significant benefit compared to control.The small number of studies (11 RCTs) limited ability to define effective delivery methods.

View Article: PubMed Central - PubMed

Affiliation: Division of Cardiovascular Medicine, Cardiovascular Clinical Research Facility, University of Oxford, Oxford, UK.

No MeSH data available.


Related in: MedlinePlus