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Behavioural physical activity interventions in participants with lower-limb osteoarthritis: a systematic review with meta-analysis.

Williamson W, Kluzek S, Roberts N, Richards J, Arden N, Leeson P, Newton J, Foster C - BMJ Open (2015)

Bottom Line: Subgroup analysis of 6-12 month outcome reduced heterogeneity and increased intervention effect compared to control (SMD 0.53, 95% CI 0.41 to 0.65, z=8.84 (p<0.00001) I(2) of 66%).Effectiveness of intervention declines with extended follow-up beyond 12 months with no significant benefit compared to control.The small number of studies (11 RCTs) limited ability to define effective delivery methods.

View Article: PubMed Central - PubMed

Affiliation: Division of Cardiovascular Medicine, Cardiovascular Clinical Research Facility, University of Oxford, Oxford, UK.

No MeSH data available.


Related in: MedlinePlus

PRISMA flow diagram; randomised controlled trail study selection.
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BMJOPEN2015007642F1: PRISMA flow diagram; randomised controlled trail study selection.

Mentions: The literature search yielded 27 984 articles from across the physical activity and exercise literature. The majority of studies were excluded following review of titles and abstracts as not meeting the major inclusion criteria outlined in the study protocol. Of the 180 articles selected for critical reading (figure 1), 169 were excluded with explanation (see online supplementary file appendix 1). The majority of excluded randomised comparison trials report no or insufficient measures of physical activity (n=77).


Behavioural physical activity interventions in participants with lower-limb osteoarthritis: a systematic review with meta-analysis.

Williamson W, Kluzek S, Roberts N, Richards J, Arden N, Leeson P, Newton J, Foster C - BMJ Open (2015)

PRISMA flow diagram; randomised controlled trail study selection.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4538274&req=5

BMJOPEN2015007642F1: PRISMA flow diagram; randomised controlled trail study selection.
Mentions: The literature search yielded 27 984 articles from across the physical activity and exercise literature. The majority of studies were excluded following review of titles and abstracts as not meeting the major inclusion criteria outlined in the study protocol. Of the 180 articles selected for critical reading (figure 1), 169 were excluded with explanation (see online supplementary file appendix 1). The majority of excluded randomised comparison trials report no or insufficient measures of physical activity (n=77).

Bottom Line: Subgroup analysis of 6-12 month outcome reduced heterogeneity and increased intervention effect compared to control (SMD 0.53, 95% CI 0.41 to 0.65, z=8.84 (p<0.00001) I(2) of 66%).Effectiveness of intervention declines with extended follow-up beyond 12 months with no significant benefit compared to control.The small number of studies (11 RCTs) limited ability to define effective delivery methods.

View Article: PubMed Central - PubMed

Affiliation: Division of Cardiovascular Medicine, Cardiovascular Clinical Research Facility, University of Oxford, Oxford, UK.

No MeSH data available.


Related in: MedlinePlus