Limits...
Adiposity and blood pressure among 55 000 relatively lean rural adults in southwest of China.

Chen X, Du H, Zhang J, Chen X, Luo G, Que X, Zhang N, Bian Z, Guo Y, Li L, Chen Z, Wu X - J Hum Hypertens (2015)

Bottom Line: There was a strongly positive, and apparently linear, relationship of BMI and WC with blood pressure, with 1 s.d. higher BMI associated with 4.3/2.3 mm Hg higher SBP/DBP and 1 s.d.WC associated with 3.8/2.1 mm Hg (P<0.0001).Additional adjustment for WC only slightly attenuated the association of BMI with blood pressure, whereas additional adjustment for BMI almost completely eliminated the association of WC with blood pressure.

View Article: PubMed Central - PubMed

Affiliation: 1] West China School of Public Health, Sichuan University, Sichuan Province, China [2] Sichuan Provincial Center of Disease Prevention and Control, Sichuan Province, China.

ABSTRACT
Obesity is a strong determinant of blood pressure. Uncertainty remains, however, about which indices of adiposity most strongly predict blood pressure, particularly among those who were relatively lean, such as those from rural China. We analyzed cross-sectional data on 55 ,687 (38.3% men) participants aged 30-79 years who were enrolled into the China Kadoorie Biobank from a rural county in southwest of China during 2004-2008. Measured body mass index (BMI) and waist circumference (WC) were related to blood pressure in multivariable linear regression analyses. The overall mean values of BMI, WC, systolic blood pressure (SBP) and diastolic blood pressure (DBP) were 23.3 kg m(-2), 78.0 cm, 129.2 mm Hg and 77.2 mm Hg, respectively. There was a strongly positive, and apparently linear, relationship of BMI and WC with blood pressure, with 1 s.d. higher BMI associated with 4.3/2.3 mm Hg higher SBP/DBP and 1 s.d. WC associated with 3.8/2.1 mm Hg (P<0.0001). Additional adjustment for WC only slightly attenuated the association of BMI with blood pressure, whereas additional adjustment for BMI almost completely eliminated the association of WC with blood pressure. Our findings suggest that in relatively lean Chinese adults, general adiposity is more strongly assciated with blood pressure than central adiposity.

No MeSH data available.


Related in: MedlinePlus

Increment of systolic blood pressure for each 5 kg m−2 BMI increase in different subgroups (n=53 578)*. SBP differences were calculated with adjustment for age, education, annual household income, smoking, alcohol and fruit consumption, sedentary leisure time and season.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4537884&req=5

fig3: Increment of systolic blood pressure for each 5 kg m−2 BMI increase in different subgroups (n=53 578)*. SBP differences were calculated with adjustment for age, education, annual household income, smoking, alcohol and fruit consumption, sedentary leisure time and season.

Mentions: After adjusting for potential confounders, each 5 kg m−2 BMI higher was on average associated with 6.7 mm Hg (95% CI: 6.5, 6.9) higher SBP (7.2 mm Hg in men and 6.3 mm Hg in women), with the association being stronger in older than in younger people (5.2 mm Hg at 30–39 years vs 7.7 mm Hg at age 70 or above; Figure 3). The association was also much stronger in ex-regular alcohol drinkers. As shown in Supplementary Figure 2, every 5 kg m−2 higher BMI was associated with 3.6 (3.5, 3.7) mm Hg DBP, with the association being stronger in men and in ex-regular drinkers. But no age trend was seen.


Adiposity and blood pressure among 55 000 relatively lean rural adults in southwest of China.

Chen X, Du H, Zhang J, Chen X, Luo G, Que X, Zhang N, Bian Z, Guo Y, Li L, Chen Z, Wu X - J Hum Hypertens (2015)

Increment of systolic blood pressure for each 5 kg m−2 BMI increase in different subgroups (n=53 578)*. SBP differences were calculated with adjustment for age, education, annual household income, smoking, alcohol and fruit consumption, sedentary leisure time and season.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4537884&req=5

fig3: Increment of systolic blood pressure for each 5 kg m−2 BMI increase in different subgroups (n=53 578)*. SBP differences were calculated with adjustment for age, education, annual household income, smoking, alcohol and fruit consumption, sedentary leisure time and season.
Mentions: After adjusting for potential confounders, each 5 kg m−2 BMI higher was on average associated with 6.7 mm Hg (95% CI: 6.5, 6.9) higher SBP (7.2 mm Hg in men and 6.3 mm Hg in women), with the association being stronger in older than in younger people (5.2 mm Hg at 30–39 years vs 7.7 mm Hg at age 70 or above; Figure 3). The association was also much stronger in ex-regular alcohol drinkers. As shown in Supplementary Figure 2, every 5 kg m−2 higher BMI was associated with 3.6 (3.5, 3.7) mm Hg DBP, with the association being stronger in men and in ex-regular drinkers. But no age trend was seen.

Bottom Line: There was a strongly positive, and apparently linear, relationship of BMI and WC with blood pressure, with 1 s.d. higher BMI associated with 4.3/2.3 mm Hg higher SBP/DBP and 1 s.d.WC associated with 3.8/2.1 mm Hg (P<0.0001).Additional adjustment for WC only slightly attenuated the association of BMI with blood pressure, whereas additional adjustment for BMI almost completely eliminated the association of WC with blood pressure.

View Article: PubMed Central - PubMed

Affiliation: 1] West China School of Public Health, Sichuan University, Sichuan Province, China [2] Sichuan Provincial Center of Disease Prevention and Control, Sichuan Province, China.

ABSTRACT
Obesity is a strong determinant of blood pressure. Uncertainty remains, however, about which indices of adiposity most strongly predict blood pressure, particularly among those who were relatively lean, such as those from rural China. We analyzed cross-sectional data on 55 ,687 (38.3% men) participants aged 30-79 years who were enrolled into the China Kadoorie Biobank from a rural county in southwest of China during 2004-2008. Measured body mass index (BMI) and waist circumference (WC) were related to blood pressure in multivariable linear regression analyses. The overall mean values of BMI, WC, systolic blood pressure (SBP) and diastolic blood pressure (DBP) were 23.3 kg m(-2), 78.0 cm, 129.2 mm Hg and 77.2 mm Hg, respectively. There was a strongly positive, and apparently linear, relationship of BMI and WC with blood pressure, with 1 s.d. higher BMI associated with 4.3/2.3 mm Hg higher SBP/DBP and 1 s.d. WC associated with 3.8/2.1 mm Hg (P<0.0001). Additional adjustment for WC only slightly attenuated the association of BMI with blood pressure, whereas additional adjustment for BMI almost completely eliminated the association of WC with blood pressure. Our findings suggest that in relatively lean Chinese adults, general adiposity is more strongly assciated with blood pressure than central adiposity.

No MeSH data available.


Related in: MedlinePlus