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Adiposity and blood pressure among 55 000 relatively lean rural adults in southwest of China.

Chen X, Du H, Zhang J, Chen X, Luo G, Que X, Zhang N, Bian Z, Guo Y, Li L, Chen Z, Wu X - J Hum Hypertens (2015)

Bottom Line: There was a strongly positive, and apparently linear, relationship of BMI and WC with blood pressure, with 1 s.d. higher BMI associated with 4.3/2.3 mm Hg higher SBP/DBP and 1 s.d.WC associated with 3.8/2.1 mm Hg (P<0.0001).Additional adjustment for WC only slightly attenuated the association of BMI with blood pressure, whereas additional adjustment for BMI almost completely eliminated the association of WC with blood pressure.

View Article: PubMed Central - PubMed

Affiliation: 1] West China School of Public Health, Sichuan University, Sichuan Province, China [2] Sichuan Provincial Center of Disease Prevention and Control, Sichuan Province, China.

ABSTRACT
Obesity is a strong determinant of blood pressure. Uncertainty remains, however, about which indices of adiposity most strongly predict blood pressure, particularly among those who were relatively lean, such as those from rural China. We analyzed cross-sectional data on 55 ,687 (38.3% men) participants aged 30-79 years who were enrolled into the China Kadoorie Biobank from a rural county in southwest of China during 2004-2008. Measured body mass index (BMI) and waist circumference (WC) were related to blood pressure in multivariable linear regression analyses. The overall mean values of BMI, WC, systolic blood pressure (SBP) and diastolic blood pressure (DBP) were 23.3 kg m(-2), 78.0 cm, 129.2 mm Hg and 77.2 mm Hg, respectively. There was a strongly positive, and apparently linear, relationship of BMI and WC with blood pressure, with 1 s.d. higher BMI associated with 4.3/2.3 mm Hg higher SBP/DBP and 1 s.d. WC associated with 3.8/2.1 mm Hg (P<0.0001). Additional adjustment for WC only slightly attenuated the association of BMI with blood pressure, whereas additional adjustment for BMI almost completely eliminated the association of WC with blood pressure. Our findings suggest that in relatively lean Chinese adults, general adiposity is more strongly assciated with blood pressure than central adiposity.

No MeSH data available.


Related in: MedlinePlus

Systolic blood pressure (SBP) in relation to body mass index (BMI), a and waist circumference (WC), b among 53 578 participants. The means of SBP were calculated for each BMI and WC group, with adjustment for age, education, annual household income, smoking, alcohol and fruit consumption, sedentary leisure time, season and with/without the adjustment for each other.
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fig2: Systolic blood pressure (SBP) in relation to body mass index (BMI), a and waist circumference (WC), b among 53 578 participants. The means of SBP were calculated for each BMI and WC group, with adjustment for age, education, annual household income, smoking, alcohol and fruit consumption, sedentary leisure time, season and with/without the adjustment for each other.

Mentions: As shown in Figure 2, both BMI and WC were strongly and positively associated with SBP, before adjusting for each other, with 1 s.d. higher BMI (3.2 kg m−2) associated with 4.3 mm Hg (95% CI: 4.2–4.4) and 1 s.d. WC (8.9 cm) associated with 3.8 mm Hg (3.6–3.9). After the additional adjustment for WC, the associations of BMI with SBP were only slightly attenuated to 3.8 mm Hg (3.5–4.0). However, the additional adjustment for BMI almost completely eliminated the associations between WC and blood pressure, down to 0.6 mm Hg (0.3–0.9; P<0.001). Similar was observed for DBP: additional adjustment for WC only slightly attenuated the associations of BMI with DBP from 2.3 to 1.8 mm Hg for per s.d. BMI, while additional adjustment for BMI dramatically reduced the association of WC with DBP from 2.1 to 0.6 mm Hg per s.d. WC (Supplementary Figure 1).


Adiposity and blood pressure among 55 000 relatively lean rural adults in southwest of China.

Chen X, Du H, Zhang J, Chen X, Luo G, Que X, Zhang N, Bian Z, Guo Y, Li L, Chen Z, Wu X - J Hum Hypertens (2015)

Systolic blood pressure (SBP) in relation to body mass index (BMI), a and waist circumference (WC), b among 53 578 participants. The means of SBP were calculated for each BMI and WC group, with adjustment for age, education, annual household income, smoking, alcohol and fruit consumption, sedentary leisure time, season and with/without the adjustment for each other.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4537884&req=5

fig2: Systolic blood pressure (SBP) in relation to body mass index (BMI), a and waist circumference (WC), b among 53 578 participants. The means of SBP were calculated for each BMI and WC group, with adjustment for age, education, annual household income, smoking, alcohol and fruit consumption, sedentary leisure time, season and with/without the adjustment for each other.
Mentions: As shown in Figure 2, both BMI and WC were strongly and positively associated with SBP, before adjusting for each other, with 1 s.d. higher BMI (3.2 kg m−2) associated with 4.3 mm Hg (95% CI: 4.2–4.4) and 1 s.d. WC (8.9 cm) associated with 3.8 mm Hg (3.6–3.9). After the additional adjustment for WC, the associations of BMI with SBP were only slightly attenuated to 3.8 mm Hg (3.5–4.0). However, the additional adjustment for BMI almost completely eliminated the associations between WC and blood pressure, down to 0.6 mm Hg (0.3–0.9; P<0.001). Similar was observed for DBP: additional adjustment for WC only slightly attenuated the associations of BMI with DBP from 2.3 to 1.8 mm Hg for per s.d. BMI, while additional adjustment for BMI dramatically reduced the association of WC with DBP from 2.1 to 0.6 mm Hg per s.d. WC (Supplementary Figure 1).

Bottom Line: There was a strongly positive, and apparently linear, relationship of BMI and WC with blood pressure, with 1 s.d. higher BMI associated with 4.3/2.3 mm Hg higher SBP/DBP and 1 s.d.WC associated with 3.8/2.1 mm Hg (P<0.0001).Additional adjustment for WC only slightly attenuated the association of BMI with blood pressure, whereas additional adjustment for BMI almost completely eliminated the association of WC with blood pressure.

View Article: PubMed Central - PubMed

Affiliation: 1] West China School of Public Health, Sichuan University, Sichuan Province, China [2] Sichuan Provincial Center of Disease Prevention and Control, Sichuan Province, China.

ABSTRACT
Obesity is a strong determinant of blood pressure. Uncertainty remains, however, about which indices of adiposity most strongly predict blood pressure, particularly among those who were relatively lean, such as those from rural China. We analyzed cross-sectional data on 55 ,687 (38.3% men) participants aged 30-79 years who were enrolled into the China Kadoorie Biobank from a rural county in southwest of China during 2004-2008. Measured body mass index (BMI) and waist circumference (WC) were related to blood pressure in multivariable linear regression analyses. The overall mean values of BMI, WC, systolic blood pressure (SBP) and diastolic blood pressure (DBP) were 23.3 kg m(-2), 78.0 cm, 129.2 mm Hg and 77.2 mm Hg, respectively. There was a strongly positive, and apparently linear, relationship of BMI and WC with blood pressure, with 1 s.d. higher BMI associated with 4.3/2.3 mm Hg higher SBP/DBP and 1 s.d. WC associated with 3.8/2.1 mm Hg (P<0.0001). Additional adjustment for WC only slightly attenuated the association of BMI with blood pressure, whereas additional adjustment for BMI almost completely eliminated the association of WC with blood pressure. Our findings suggest that in relatively lean Chinese adults, general adiposity is more strongly assciated with blood pressure than central adiposity.

No MeSH data available.


Related in: MedlinePlus