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Adiposity and blood pressure among 55 000 relatively lean rural adults in southwest of China.

Chen X, Du H, Zhang J, Chen X, Luo G, Que X, Zhang N, Bian Z, Guo Y, Li L, Chen Z, Wu X - J Hum Hypertens (2015)

Bottom Line: There was a strongly positive, and apparently linear, relationship of BMI and WC with blood pressure, with 1 s.d. higher BMI associated with 4.3/2.3 mm Hg higher SBP/DBP and 1 s.d.WC associated with 3.8/2.1 mm Hg (P<0.0001).Additional adjustment for WC only slightly attenuated the association of BMI with blood pressure, whereas additional adjustment for BMI almost completely eliminated the association of WC with blood pressure.

View Article: PubMed Central - PubMed

Affiliation: 1] West China School of Public Health, Sichuan University, Sichuan Province, China [2] Sichuan Provincial Center of Disease Prevention and Control, Sichuan Province, China.

ABSTRACT
Obesity is a strong determinant of blood pressure. Uncertainty remains, however, about which indices of adiposity most strongly predict blood pressure, particularly among those who were relatively lean, such as those from rural China. We analyzed cross-sectional data on 55 ,687 (38.3% men) participants aged 30-79 years who were enrolled into the China Kadoorie Biobank from a rural county in southwest of China during 2004-2008. Measured body mass index (BMI) and waist circumference (WC) were related to blood pressure in multivariable linear regression analyses. The overall mean values of BMI, WC, systolic blood pressure (SBP) and diastolic blood pressure (DBP) were 23.3 kg m(-2), 78.0 cm, 129.2 mm Hg and 77.2 mm Hg, respectively. There was a strongly positive, and apparently linear, relationship of BMI and WC with blood pressure, with 1 s.d. higher BMI associated with 4.3/2.3 mm Hg higher SBP/DBP and 1 s.d. WC associated with 3.8/2.1 mm Hg (P<0.0001). Additional adjustment for WC only slightly attenuated the association of BMI with blood pressure, whereas additional adjustment for BMI almost completely eliminated the association of WC with blood pressure. Our findings suggest that in relatively lean Chinese adults, general adiposity is more strongly assciated with blood pressure than central adiposity.

No MeSH data available.


Related in: MedlinePlus

Associations of systolic blood pressure (SBP), diastolic blood pressure (DBP) and prevalence of hypertension with age. The means of blood pressure were calculated for each age group (5-year interval), adjusting for education, annual household income, smoking, alcohol and fruit consumption, sedentary leisure time and season.
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fig1: Associations of systolic blood pressure (SBP), diastolic blood pressure (DBP) and prevalence of hypertension with age. The means of blood pressure were calculated for each age group (5-year interval), adjusting for education, annual household income, smoking, alcohol and fruit consumption, sedentary leisure time and season.

Mentions: The mean BMI was 22.9 kg m−2 in men and 23.6 kg m−2 in women, and the mean WC was 78.9 and 77.4 cm, respectively. In men, more than three quarters (77.4%) had BMI<25 kg m−2, with only 1.5% being obese (BMI⩾30 kg m−2). In women, the corresponding rates were 68.5 and 3.8%, respectively (Tables 2 and 3). According to WC, 87.8% men and 62.3% women had no central obesity. With the exception of the youngest groups (30–39 years), mean BMI tended to decrease with increasing age in both men and women, but no similar trend was seen for WC. SBP showed a strongly positive relationship with age (Figure 1), with the mean SBP being 12.9 mm Hg (men) and 20.9 mm Hg (women) higher at age 70 years or above than at age 30–35 years. By contrast, no linear trend with age was seen for DBP, which increased first for about 3 mm Hg from 30–35 to 55–60 years and then decreased gradually afterwards. Prevalence of hypertension rose steadily with increasing age, with the absolute differences between youngest and oldest age groups being 39.7 and 46.1% in men and women, respectively.


Adiposity and blood pressure among 55 000 relatively lean rural adults in southwest of China.

Chen X, Du H, Zhang J, Chen X, Luo G, Que X, Zhang N, Bian Z, Guo Y, Li L, Chen Z, Wu X - J Hum Hypertens (2015)

Associations of systolic blood pressure (SBP), diastolic blood pressure (DBP) and prevalence of hypertension with age. The means of blood pressure were calculated for each age group (5-year interval), adjusting for education, annual household income, smoking, alcohol and fruit consumption, sedentary leisure time and season.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4537884&req=5

fig1: Associations of systolic blood pressure (SBP), diastolic blood pressure (DBP) and prevalence of hypertension with age. The means of blood pressure were calculated for each age group (5-year interval), adjusting for education, annual household income, smoking, alcohol and fruit consumption, sedentary leisure time and season.
Mentions: The mean BMI was 22.9 kg m−2 in men and 23.6 kg m−2 in women, and the mean WC was 78.9 and 77.4 cm, respectively. In men, more than three quarters (77.4%) had BMI<25 kg m−2, with only 1.5% being obese (BMI⩾30 kg m−2). In women, the corresponding rates were 68.5 and 3.8%, respectively (Tables 2 and 3). According to WC, 87.8% men and 62.3% women had no central obesity. With the exception of the youngest groups (30–39 years), mean BMI tended to decrease with increasing age in both men and women, but no similar trend was seen for WC. SBP showed a strongly positive relationship with age (Figure 1), with the mean SBP being 12.9 mm Hg (men) and 20.9 mm Hg (women) higher at age 70 years or above than at age 30–35 years. By contrast, no linear trend with age was seen for DBP, which increased first for about 3 mm Hg from 30–35 to 55–60 years and then decreased gradually afterwards. Prevalence of hypertension rose steadily with increasing age, with the absolute differences between youngest and oldest age groups being 39.7 and 46.1% in men and women, respectively.

Bottom Line: There was a strongly positive, and apparently linear, relationship of BMI and WC with blood pressure, with 1 s.d. higher BMI associated with 4.3/2.3 mm Hg higher SBP/DBP and 1 s.d.WC associated with 3.8/2.1 mm Hg (P<0.0001).Additional adjustment for WC only slightly attenuated the association of BMI with blood pressure, whereas additional adjustment for BMI almost completely eliminated the association of WC with blood pressure.

View Article: PubMed Central - PubMed

Affiliation: 1] West China School of Public Health, Sichuan University, Sichuan Province, China [2] Sichuan Provincial Center of Disease Prevention and Control, Sichuan Province, China.

ABSTRACT
Obesity is a strong determinant of blood pressure. Uncertainty remains, however, about which indices of adiposity most strongly predict blood pressure, particularly among those who were relatively lean, such as those from rural China. We analyzed cross-sectional data on 55 ,687 (38.3% men) participants aged 30-79 years who were enrolled into the China Kadoorie Biobank from a rural county in southwest of China during 2004-2008. Measured body mass index (BMI) and waist circumference (WC) were related to blood pressure in multivariable linear regression analyses. The overall mean values of BMI, WC, systolic blood pressure (SBP) and diastolic blood pressure (DBP) were 23.3 kg m(-2), 78.0 cm, 129.2 mm Hg and 77.2 mm Hg, respectively. There was a strongly positive, and apparently linear, relationship of BMI and WC with blood pressure, with 1 s.d. higher BMI associated with 4.3/2.3 mm Hg higher SBP/DBP and 1 s.d. WC associated with 3.8/2.1 mm Hg (P<0.0001). Additional adjustment for WC only slightly attenuated the association of BMI with blood pressure, whereas additional adjustment for BMI almost completely eliminated the association of WC with blood pressure. Our findings suggest that in relatively lean Chinese adults, general adiposity is more strongly assciated with blood pressure than central adiposity.

No MeSH data available.


Related in: MedlinePlus