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Massive Neurilemoma of the Hard Plate in Which Preoperative Diagnosis Was Difficult.

Kudoh M, Harada H, Matsumoto K, Sato Y, Omura K, Ishii Y - Case Rep Surg (2015)

Bottom Line: The mass was a solid tumor associated with resorption of surrounding bone and expansion of the greater palatine canal.The histopathological diagnosis was a suspected malignant neurogenic tumor.No recurrence was noted 29 months after the operation.

View Article: PubMed Central - PubMed

Affiliation: Division of Oral and Maxillofacial Surgery, Ebina General Hospital, 1320 Kawaraguchi, Ebina City, Kanagawa 243-0433, Japan ; Oral and Maxillofacial Surgery, Department of Oral Restitution, Division of Oral Health Sciences, Graduate School, Tokyo Medical and Dental University, Japan.

ABSTRACT
The patient was an 84-year-old man who was referred to our hospital in mid-December 2012 for a close examination of a mass arising from the left side of the hard palate that was found by a local dentist. The initial examination revealed the presence of a 3.0-cm elastic soft, dome-shaped mass in the left hard palate. CE-CT showed a lesion of size 1.8 × 1.4 cm in the right hard palate, which extended upward and invaded the nasal cavity. The mass was a solid tumor associated with resorption of surrounding bone and expansion of the greater palatine canal. CE-MRI indicated that the mass extended upward and invaded the nasal cavity, and the mass showed hypointensity on T1-weighted images, hyperintensity on T2-weighted images, and an irregular margin with internal enhancement. Abnormal uptake of FDG on PET-CT (SUVmax = 5.2) was observed in the left hard palate. The biopsy site lesion rapidly increased in size and biopsy was performed again in January 2013 due to suspicion of a malignant tumor. The histopathological diagnosis was a suspected malignant neurogenic tumor. Therefore, the patient underwent partial maxillectomy and a split-thickness skin graft in late February 2013. No recurrence was noted 29 months after the operation.

No MeSH data available.


Related in: MedlinePlus

After placement of a denture for a defective maxilla.
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fig13: After placement of a denture for a defective maxilla.

Mentions: Histopathologically, the surgical specimen showed disordered proliferation of spindle-shaped cells, which consisted of mainly Antoni A type showing palisading features and a small amount of Antoni B type in a slightly edematous substrate. In immunostaining, the cells were S-100 positive, the Ki-67 positive rate was approximately 1%, and neither atypical nor nuclear divisions were observed (Figure 12). Histopathology showed neurilemoma. Currently, at 29 months postoperatively, the patient is in excellent condition without recurrence. He wears a denture for a defective maxilla, and his velopharyngeal, masticatory, and articulatory functions have recovered (Figure 13).


Massive Neurilemoma of the Hard Plate in Which Preoperative Diagnosis Was Difficult.

Kudoh M, Harada H, Matsumoto K, Sato Y, Omura K, Ishii Y - Case Rep Surg (2015)

After placement of a denture for a defective maxilla.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4537717&req=5

fig13: After placement of a denture for a defective maxilla.
Mentions: Histopathologically, the surgical specimen showed disordered proliferation of spindle-shaped cells, which consisted of mainly Antoni A type showing palisading features and a small amount of Antoni B type in a slightly edematous substrate. In immunostaining, the cells were S-100 positive, the Ki-67 positive rate was approximately 1%, and neither atypical nor nuclear divisions were observed (Figure 12). Histopathology showed neurilemoma. Currently, at 29 months postoperatively, the patient is in excellent condition without recurrence. He wears a denture for a defective maxilla, and his velopharyngeal, masticatory, and articulatory functions have recovered (Figure 13).

Bottom Line: The mass was a solid tumor associated with resorption of surrounding bone and expansion of the greater palatine canal.The histopathological diagnosis was a suspected malignant neurogenic tumor.No recurrence was noted 29 months after the operation.

View Article: PubMed Central - PubMed

Affiliation: Division of Oral and Maxillofacial Surgery, Ebina General Hospital, 1320 Kawaraguchi, Ebina City, Kanagawa 243-0433, Japan ; Oral and Maxillofacial Surgery, Department of Oral Restitution, Division of Oral Health Sciences, Graduate School, Tokyo Medical and Dental University, Japan.

ABSTRACT
The patient was an 84-year-old man who was referred to our hospital in mid-December 2012 for a close examination of a mass arising from the left side of the hard palate that was found by a local dentist. The initial examination revealed the presence of a 3.0-cm elastic soft, dome-shaped mass in the left hard palate. CE-CT showed a lesion of size 1.8 × 1.4 cm in the right hard palate, which extended upward and invaded the nasal cavity. The mass was a solid tumor associated with resorption of surrounding bone and expansion of the greater palatine canal. CE-MRI indicated that the mass extended upward and invaded the nasal cavity, and the mass showed hypointensity on T1-weighted images, hyperintensity on T2-weighted images, and an irregular margin with internal enhancement. Abnormal uptake of FDG on PET-CT (SUVmax = 5.2) was observed in the left hard palate. The biopsy site lesion rapidly increased in size and biopsy was performed again in January 2013 due to suspicion of a malignant tumor. The histopathological diagnosis was a suspected malignant neurogenic tumor. Therefore, the patient underwent partial maxillectomy and a split-thickness skin graft in late February 2013. No recurrence was noted 29 months after the operation.

No MeSH data available.


Related in: MedlinePlus