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Network Interactions Explain Sensitivity to Dynamic Faces in the Superior Temporal Sulcus.

Furl N, Henson RN, Friston KJ, Calder AJ - Cereb. Cortex (2014)

Bottom Line: The superior temporal sulcus (STS) in the human and monkey is sensitive to the motion of complex forms such as facial and bodily actions.We then tested various connectivity models that modeled communication between the ventral form and dorsal motion pathways.We show that facial form information modulated transmission of motion information from V5 to the STS, and that this face-selective modulation likely originated in OFA.

View Article: PubMed Central - PubMed

Affiliation: MRC Cognition and Brain Sciences Unit, Cambridge CB2 7EF, UK.

No MeSH data available.


Related in: MedlinePlus

Optimal dynamic causal models (a) the optimal bilinear model generates motion sensitivity that is selective to facial form in the superior temporal sulcus (STS) when faces modulate connections from the motion-sensitive V5 to STS. Bilinear modulations indicated by black arrows, endogenous connections indicated in light gray. The optimal model had full endogenous connectivity. (b) The optimal nonlinear model shows that the face-selective occipital face area (OFA) is the most likely origin of face modulation on the connections from V5 to STS. Bilinear and nonlinear modulations indicated by black arrows, endogenous connections indicated in light gray. FFA, fusiform face area, BA18, Brodmann area 18.
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BHU083F3: Optimal dynamic causal models (a) the optimal bilinear model generates motion sensitivity that is selective to facial form in the superior temporal sulcus (STS) when faces modulate connections from the motion-sensitive V5 to STS. Bilinear modulations indicated by black arrows, endogenous connections indicated in light gray. The optimal model had full endogenous connectivity. (b) The optimal nonlinear model shows that the face-selective occipital face area (OFA) is the most likely origin of face modulation on the connections from V5 to STS. Bilinear and nonlinear modulations indicated by black arrows, endogenous connections indicated in light gray. FFA, fusiform face area, BA18, Brodmann area 18.

Mentions: Our ROI analysis confirmed the presence of dorsal temporal motion sensitivity in V5, facial motion sensitivity in the STS, and ventral temporal face selectivity in the OFA and FFA. We used connectivity modeling to test how interactions between the dorsal motion-sensitive and the ventral face-selective pathways could give rise to motion sensitivity that is selective to faces in the STS. We first compared bilinear models to test whether STS responses might be explained by a network, either in which faces modulate dorsal motion-sensitive pathway connections from V5 to STS (Fig. 3), or in which motion modulates the ventral face-selective pathway connections from the OFA and/or FFA to the STS. This space of bilinear models further explored as secondary hypotheses whether (a) endogenous connectivity is full or sparse and (b) face selectivity in the ventral pathway arises from modulation by faces on only forward connections to the OFA, or if forward connections to the FFA are modulated by faces as well (OFA only and OFA/FFA rows in Table 1). Of the 16 models we tested, we found a high posterior probability (near 1.0) favoring a model where faces modulate the dorsal motion-sensitive connections from V5 to the STS. For our secondary hypotheses, we found (a) full (rather than sparse) endogenous connectivity and (b) face modulation on connections from BA18 to the OFA only (and not also to the FFA). These properties of the optimal model were confirmed using model family comparisons (Table 2).Figure 3.


Network Interactions Explain Sensitivity to Dynamic Faces in the Superior Temporal Sulcus.

Furl N, Henson RN, Friston KJ, Calder AJ - Cereb. Cortex (2014)

Optimal dynamic causal models (a) the optimal bilinear model generates motion sensitivity that is selective to facial form in the superior temporal sulcus (STS) when faces modulate connections from the motion-sensitive V5 to STS. Bilinear modulations indicated by black arrows, endogenous connections indicated in light gray. The optimal model had full endogenous connectivity. (b) The optimal nonlinear model shows that the face-selective occipital face area (OFA) is the most likely origin of face modulation on the connections from V5 to STS. Bilinear and nonlinear modulations indicated by black arrows, endogenous connections indicated in light gray. FFA, fusiform face area, BA18, Brodmann area 18.
© Copyright Policy - creative-commons
Related In: Results  -  Collection

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getmorefigures.php?uid=PMC4537434&req=5

BHU083F3: Optimal dynamic causal models (a) the optimal bilinear model generates motion sensitivity that is selective to facial form in the superior temporal sulcus (STS) when faces modulate connections from the motion-sensitive V5 to STS. Bilinear modulations indicated by black arrows, endogenous connections indicated in light gray. The optimal model had full endogenous connectivity. (b) The optimal nonlinear model shows that the face-selective occipital face area (OFA) is the most likely origin of face modulation on the connections from V5 to STS. Bilinear and nonlinear modulations indicated by black arrows, endogenous connections indicated in light gray. FFA, fusiform face area, BA18, Brodmann area 18.
Mentions: Our ROI analysis confirmed the presence of dorsal temporal motion sensitivity in V5, facial motion sensitivity in the STS, and ventral temporal face selectivity in the OFA and FFA. We used connectivity modeling to test how interactions between the dorsal motion-sensitive and the ventral face-selective pathways could give rise to motion sensitivity that is selective to faces in the STS. We first compared bilinear models to test whether STS responses might be explained by a network, either in which faces modulate dorsal motion-sensitive pathway connections from V5 to STS (Fig. 3), or in which motion modulates the ventral face-selective pathway connections from the OFA and/or FFA to the STS. This space of bilinear models further explored as secondary hypotheses whether (a) endogenous connectivity is full or sparse and (b) face selectivity in the ventral pathway arises from modulation by faces on only forward connections to the OFA, or if forward connections to the FFA are modulated by faces as well (OFA only and OFA/FFA rows in Table 1). Of the 16 models we tested, we found a high posterior probability (near 1.0) favoring a model where faces modulate the dorsal motion-sensitive connections from V5 to the STS. For our secondary hypotheses, we found (a) full (rather than sparse) endogenous connectivity and (b) face modulation on connections from BA18 to the OFA only (and not also to the FFA). These properties of the optimal model were confirmed using model family comparisons (Table 2).Figure 3.

Bottom Line: The superior temporal sulcus (STS) in the human and monkey is sensitive to the motion of complex forms such as facial and bodily actions.We then tested various connectivity models that modeled communication between the ventral form and dorsal motion pathways.We show that facial form information modulated transmission of motion information from V5 to the STS, and that this face-selective modulation likely originated in OFA.

View Article: PubMed Central - PubMed

Affiliation: MRC Cognition and Brain Sciences Unit, Cambridge CB2 7EF, UK.

No MeSH data available.


Related in: MedlinePlus