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Reflections of Oneself: Neurocognitive Evidence for Dissociable Forms of Self-Referential Recollection.

Bergström ZM, Vogelsang DA, Benoit RG, Simons JS - Cereb. Cortex (2014)

Bottom Line: The dorsal mPFC was generally activated when participants attempted to retrieve social information about themselves and others, regardless of whether this information concerned the conceptual or agentic self or other.In contrast, a role was discerned for ventral mPFC during conceptual but not agentic self-referential recollection, indicating specific involvement in retrieving memories related to self-concept rather than bodily self.A subsequent recognition test for new items that had been presented during the recollection task found that conceptual and agentic recollection attempts resulted in differential incidental encoding of new information.

View Article: PubMed Central - PubMed

Affiliation: Department of Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK School of Psychology, Keynes College, University of Kent, Canterbury CT2 7NP, UK.

No MeSH data available.


Related in: MedlinePlus

fMRI activations in the mPFC associated with self/other recollection. Effects in A and B are thresholded at P < 0.001 (uncorrected), with a minimum cluster size of 10 voxels, and inclusively masked to display only activations within the mPFC region associated with social cognition in Amodio and Frith (2006). Effects in (C) are thresholded at P < 0.05 family-wise error corrected for the whole brain, with a minimum cluster size of 10 voxels. The percent signal change bar graphs (A and B) plot the mean difference between each displayed condition and the nonepisodic Control task extracted from the peak voxel in each mPFC cluster. (A) A dorsal mPFC region with a peak at [−12, 59, 25] showed enhanced activation for both old and new items in both recollection tasks, compared with the Control condition. (B) a ventral mPFC region with a peak at [−9, 53, 13] showed selective activation for old items that participants had processed in relation to their conceptual self during study, and only when the retrieval task required recollection of conceptual self/other information. (C) In a whole-brain analysis, general old > new effects (old > new collapsed across retrieval task; red) were associated with a very different activation pattern from episodic retrieval task effects (episodic tasks > Control task; green), except in the precuneus where the 2 effects overlapped.
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BHU063F2: fMRI activations in the mPFC associated with self/other recollection. Effects in A and B are thresholded at P < 0.001 (uncorrected), with a minimum cluster size of 10 voxels, and inclusively masked to display only activations within the mPFC region associated with social cognition in Amodio and Frith (2006). Effects in (C) are thresholded at P < 0.05 family-wise error corrected for the whole brain, with a minimum cluster size of 10 voxels. The percent signal change bar graphs (A and B) plot the mean difference between each displayed condition and the nonepisodic Control task extracted from the peak voxel in each mPFC cluster. (A) A dorsal mPFC region with a peak at [−12, 59, 25] showed enhanced activation for both old and new items in both recollection tasks, compared with the Control condition. (B) a ventral mPFC region with a peak at [−9, 53, 13] showed selective activation for old items that participants had processed in relation to their conceptual self during study, and only when the retrieval task required recollection of conceptual self/other information. (C) In a whole-brain analysis, general old > new effects (old > new collapsed across retrieval task; red) were associated with a very different activation pattern from episodic retrieval task effects (episodic tasks > Control task; green), except in the precuneus where the 2 effects overlapped.

Mentions: A region of interest (ROI) analysis focusing on the mPFC region that has previously been implicated in social cognition (using a mask based on coordinates identified by Amodio and Frith (2006) for small-volume correction) confirmed that all episodic conditions did indeed activate a relatively dorsal cluster in the left mPFC (Table 2; Fig. 2A). An exploratory analysis testing for regions outside the mPFC that were commonly activated for old and new items in both retrieval tasks showed further activations in the medial parietal and left lateral temporo-parietal cortex, left inferior frontal and left middle temporal regions (Table 2).Table 2


Reflections of Oneself: Neurocognitive Evidence for Dissociable Forms of Self-Referential Recollection.

Bergström ZM, Vogelsang DA, Benoit RG, Simons JS - Cereb. Cortex (2014)

fMRI activations in the mPFC associated with self/other recollection. Effects in A and B are thresholded at P < 0.001 (uncorrected), with a minimum cluster size of 10 voxels, and inclusively masked to display only activations within the mPFC region associated with social cognition in Amodio and Frith (2006). Effects in (C) are thresholded at P < 0.05 family-wise error corrected for the whole brain, with a minimum cluster size of 10 voxels. The percent signal change bar graphs (A and B) plot the mean difference between each displayed condition and the nonepisodic Control task extracted from the peak voxel in each mPFC cluster. (A) A dorsal mPFC region with a peak at [−12, 59, 25] showed enhanced activation for both old and new items in both recollection tasks, compared with the Control condition. (B) a ventral mPFC region with a peak at [−9, 53, 13] showed selective activation for old items that participants had processed in relation to their conceptual self during study, and only when the retrieval task required recollection of conceptual self/other information. (C) In a whole-brain analysis, general old > new effects (old > new collapsed across retrieval task; red) were associated with a very different activation pattern from episodic retrieval task effects (episodic tasks > Control task; green), except in the precuneus where the 2 effects overlapped.
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4537426&req=5

BHU063F2: fMRI activations in the mPFC associated with self/other recollection. Effects in A and B are thresholded at P < 0.001 (uncorrected), with a minimum cluster size of 10 voxels, and inclusively masked to display only activations within the mPFC region associated with social cognition in Amodio and Frith (2006). Effects in (C) are thresholded at P < 0.05 family-wise error corrected for the whole brain, with a minimum cluster size of 10 voxels. The percent signal change bar graphs (A and B) plot the mean difference between each displayed condition and the nonepisodic Control task extracted from the peak voxel in each mPFC cluster. (A) A dorsal mPFC region with a peak at [−12, 59, 25] showed enhanced activation for both old and new items in both recollection tasks, compared with the Control condition. (B) a ventral mPFC region with a peak at [−9, 53, 13] showed selective activation for old items that participants had processed in relation to their conceptual self during study, and only when the retrieval task required recollection of conceptual self/other information. (C) In a whole-brain analysis, general old > new effects (old > new collapsed across retrieval task; red) were associated with a very different activation pattern from episodic retrieval task effects (episodic tasks > Control task; green), except in the precuneus where the 2 effects overlapped.
Mentions: A region of interest (ROI) analysis focusing on the mPFC region that has previously been implicated in social cognition (using a mask based on coordinates identified by Amodio and Frith (2006) for small-volume correction) confirmed that all episodic conditions did indeed activate a relatively dorsal cluster in the left mPFC (Table 2; Fig. 2A). An exploratory analysis testing for regions outside the mPFC that were commonly activated for old and new items in both retrieval tasks showed further activations in the medial parietal and left lateral temporo-parietal cortex, left inferior frontal and left middle temporal regions (Table 2).Table 2

Bottom Line: The dorsal mPFC was generally activated when participants attempted to retrieve social information about themselves and others, regardless of whether this information concerned the conceptual or agentic self or other.In contrast, a role was discerned for ventral mPFC during conceptual but not agentic self-referential recollection, indicating specific involvement in retrieving memories related to self-concept rather than bodily self.A subsequent recognition test for new items that had been presented during the recollection task found that conceptual and agentic recollection attempts resulted in differential incidental encoding of new information.

View Article: PubMed Central - PubMed

Affiliation: Department of Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK Behavioural and Clinical Neuroscience Institute, University of Cambridge, Downing Street, Cambridge CB2 3EB, UK School of Psychology, Keynes College, University of Kent, Canterbury CT2 7NP, UK.

No MeSH data available.


Related in: MedlinePlus