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Gelfoam embolization or 125I seed implantation may be a more effective treatment than surgical treatment for giant benign sacral neurogenic tumors.

Ma X, Wei S, Yang C, Hua Y, Shen J, Cai Z - World J Surg Oncol (2015)

Bottom Line: In non-surgical group, CT-guided 125I seed implantation or GSP embolization was applied to occlude vessels.Two of the five patients were treated three times with GSP embolization, one had received GSP embolization combined with CT-guided 125I seed implantation, one case did not receive any treatment, and one patient was lost to follow-up.Patients in non-surgical group were followed up for 2-8 years.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopedics, Tongji University, Shanghai Tenth People's Hospital, 301 Yanchang Rd, Shanghai, 200072, China. XiaojunMaxjm@163.com.

ABSTRACT

Background: The goal of the present study was to assess the effects of computed tomography (CT)-guided iodine-125 (125I) seed implantation or gelatin sponge particle (GSP) embolization on patients with giant benign sacral neurogenic tumors.

Methods: A total of 24 cases with giant sacral neurogenic tumor were performed in a retrospective study between 2000 and 2012. Nineteen cases received surgical resection, and five cases received non-surgical treatment. In surgical group, patients with type III sacral tumor had received a combined anterior-posterior approach and patients with type IV were treated with simple anterior approach. In non-surgical group, CT-guided 125I seed implantation or GSP embolization was applied to occlude vessels. Besides, CT scanning or magnetic resonance imaging was used to assess the size and development of tumors.

Results: Two of the five patients were treated three times with GSP embolization, one had received GSP embolization combined with CT-guided 125I seed implantation, one case did not receive any treatment, and one patient was lost to follow-up. Patients in non-surgical group were followed up for 2-8 years.

Conclusions: Our study suggested that CT-guided 125I seed implantation or GSP embolization treatment is very useful to slow down the development of giant benign sacral neurogenic tumors.

No MeSH data available.


Related in: MedlinePlus

The magnetic resonance imaging (MRI) of patient C after gelatin sponge particle (GSPs) implantation taken in July 2014
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Fig3: The magnetic resonance imaging (MRI) of patient C after gelatin sponge particle (GSPs) implantation taken in July 2014

Mentions: Patient C (51 years old, male), whose sacral lump were detected during routine physical examination, was diagnosed as sacral schwannoma with a tumor size of 12 × 9 × 6 cm. Then, the patient had received three treatments of gelfoam embolization in July 2012, April 2013, and January 2014, respectively. With a 2-year follow-up, the tumor (13 × 10 × 6 cm) was slowly aggressive (Fig. 3).Fig. 3


Gelfoam embolization or 125I seed implantation may be a more effective treatment than surgical treatment for giant benign sacral neurogenic tumors.

Ma X, Wei S, Yang C, Hua Y, Shen J, Cai Z - World J Surg Oncol (2015)

The magnetic resonance imaging (MRI) of patient C after gelatin sponge particle (GSPs) implantation taken in July 2014
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4536730&req=5

Fig3: The magnetic resonance imaging (MRI) of patient C after gelatin sponge particle (GSPs) implantation taken in July 2014
Mentions: Patient C (51 years old, male), whose sacral lump were detected during routine physical examination, was diagnosed as sacral schwannoma with a tumor size of 12 × 9 × 6 cm. Then, the patient had received three treatments of gelfoam embolization in July 2012, April 2013, and January 2014, respectively. With a 2-year follow-up, the tumor (13 × 10 × 6 cm) was slowly aggressive (Fig. 3).Fig. 3

Bottom Line: In non-surgical group, CT-guided 125I seed implantation or GSP embolization was applied to occlude vessels.Two of the five patients were treated three times with GSP embolization, one had received GSP embolization combined with CT-guided 125I seed implantation, one case did not receive any treatment, and one patient was lost to follow-up.Patients in non-surgical group were followed up for 2-8 years.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopedics, Tongji University, Shanghai Tenth People's Hospital, 301 Yanchang Rd, Shanghai, 200072, China. XiaojunMaxjm@163.com.

ABSTRACT

Background: The goal of the present study was to assess the effects of computed tomography (CT)-guided iodine-125 (125I) seed implantation or gelatin sponge particle (GSP) embolization on patients with giant benign sacral neurogenic tumors.

Methods: A total of 24 cases with giant sacral neurogenic tumor were performed in a retrospective study between 2000 and 2012. Nineteen cases received surgical resection, and five cases received non-surgical treatment. In surgical group, patients with type III sacral tumor had received a combined anterior-posterior approach and patients with type IV were treated with simple anterior approach. In non-surgical group, CT-guided 125I seed implantation or GSP embolization was applied to occlude vessels. Besides, CT scanning or magnetic resonance imaging was used to assess the size and development of tumors.

Results: Two of the five patients were treated three times with GSP embolization, one had received GSP embolization combined with CT-guided 125I seed implantation, one case did not receive any treatment, and one patient was lost to follow-up. Patients in non-surgical group were followed up for 2-8 years.

Conclusions: Our study suggested that CT-guided 125I seed implantation or GSP embolization treatment is very useful to slow down the development of giant benign sacral neurogenic tumors.

No MeSH data available.


Related in: MedlinePlus