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A malignant mixed germ cell tumor originating from the pituitary gland with a suprasellar extension: a case report.

Lim SK, Chung HC, Kim WT, Huh KB, Chung SS, Kim DI, Chung HJ - Korean J. Intern. Med. (1986)

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ABSTRACT

A case of an intracranial tumor in a 26-year old woman with symptoms of hypopituitarism, and visual disturbance is presented. The primary site has been verified by the clinical presentations and the hormonal and the neurological studies as originating from the pituitary gland with extension to the suprasellar area. Histologically, the tumor contains elements that demand its interpretation as a malignant teratoma. In a tumor marker study, the aFP level was elevated, suggestive of an endodermal sinus tumor component. We report this case as a mixed germ cell tumor originating from the pituitary gland with a suprasellar extension and a malignant transformation from a benign component.

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Left: Plain X-ray film of skull showing enlarged sella turcica, markedly eroded dorsum sellae, and intact anterior clinoid process. Right: Coronal C-T scan showing pituitary tumor with suprasellar and parasellar extension. Pressure of bulging intrasellar mass makes an acute angle between the intrasellar and the suprasellar mass (arrow).
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f1-kjim-1-2-266-22: Left: Plain X-ray film of skull showing enlarged sella turcica, markedly eroded dorsum sellae, and intact anterior clinoid process. Right: Coronal C-T scan showing pituitary tumor with suprasellar and parasellar extension. Pressure of bulging intrasellar mass makes an acute angle between the intrasellar and the suprasellar mass (arrow).

Mentions: Plain skull X-rays revealed a marked bony erosion of the dorsum of the sella. Cerebral arteriography showed a large pituitary tumor with some parasellar extension and a marked suprasellar extension. A C-T scan showed a pituitary tumor mass with a parasellar and a suprasellar extension, which was greater on the left side. Multiple low density areas were scattered in the tumor mass, representing probable tumor necrosis and hemorrhage (Fig. 1).


A malignant mixed germ cell tumor originating from the pituitary gland with a suprasellar extension: a case report.

Lim SK, Chung HC, Kim WT, Huh KB, Chung SS, Kim DI, Chung HJ - Korean J. Intern. Med. (1986)

Left: Plain X-ray film of skull showing enlarged sella turcica, markedly eroded dorsum sellae, and intact anterior clinoid process. Right: Coronal C-T scan showing pituitary tumor with suprasellar and parasellar extension. Pressure of bulging intrasellar mass makes an acute angle between the intrasellar and the suprasellar mass (arrow).
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4536722&req=5

f1-kjim-1-2-266-22: Left: Plain X-ray film of skull showing enlarged sella turcica, markedly eroded dorsum sellae, and intact anterior clinoid process. Right: Coronal C-T scan showing pituitary tumor with suprasellar and parasellar extension. Pressure of bulging intrasellar mass makes an acute angle between the intrasellar and the suprasellar mass (arrow).
Mentions: Plain skull X-rays revealed a marked bony erosion of the dorsum of the sella. Cerebral arteriography showed a large pituitary tumor with some parasellar extension and a marked suprasellar extension. A C-T scan showed a pituitary tumor mass with a parasellar and a suprasellar extension, which was greater on the left side. Multiple low density areas were scattered in the tumor mass, representing probable tumor necrosis and hemorrhage (Fig. 1).

View Article: PubMed Central - PubMed

ABSTRACT

A case of an intracranial tumor in a 26-year old woman with symptoms of hypopituitarism, and visual disturbance is presented. The primary site has been verified by the clinical presentations and the hormonal and the neurological studies as originating from the pituitary gland with extension to the suprasellar area. Histologically, the tumor contains elements that demand its interpretation as a malignant teratoma. In a tumor marker study, the aFP level was elevated, suggestive of an endodermal sinus tumor component. We report this case as a mixed germ cell tumor originating from the pituitary gland with a suprasellar extension and a malignant transformation from a benign component.

Show MeSH
Related in: MedlinePlus