Limits...
The effect of probiotic soy milk and soy milk on anthropometric measures and blood pressure in patients with type II diabetes mellitus: A randomized double-blind clinical trial.

Hariri M, Salehi R, Feizi A, Mirlohi M, Kamali S, Ghiasvand R - ARYA Atheroscler (2015)

Bottom Line: Anthropometric and BP measurements were performed according to standard protocols.Although soy milk did not have any effect on BP, probiotic soymilk significantly decreased systolic (14.7 ± 0.48 vs. 13.05 ± 0.16, P = 0.001) and diastolic BP (10 ± 0.7 vs. 9.1 ± 1, P = 0.031).In our study, probiotic soy milk in comparing with soy milk did not have any beneficial effects on anthropometric measures in these patients.

View Article: PubMed Central - PubMed

Affiliation: Hypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.

ABSTRACT

Background: The objective of this clinical trial was to assess the effects of probiotic soy milk and soy milk on anthropometric measures and blood pressure (BP) in type 2 diabetic (T2D) patients.

Methods: A total of 40 patients with T2D, 35-68 years old, were assigned to two groups in this randomized, double-blind, controlled clinical trial. The patients in the intervention group consumed 200 ml/day of probiotic soy milk containing Lactobacillus planetarium A7 and those in control group consumed 200 ml/day of soy milk for 8 weeks. Anthropometric and BP measurements were performed according to standard protocols. For detecting within-group differences paired-sample t-tests was used and analysis of covariance was used for determining any differences between two groups. (The trial has been registered in the Iranian Registry of Clinical Trials, identifier: IRCT: IRCT201405265062N8).

Results: In this study, we failed to find any significant changes between probiotic soy milk and soy milk in term of body mass index (26.65 ± 0.68 vs. 26.33 ± 0.74, P = 0.300) and waist to hip ratio (1.49 ± 0.08 vs. 1.54 ± 0.1, P = 0.170). Although soy milk did not have any effect on BP, probiotic soymilk significantly decreased systolic (14.7 ± 0.48 vs. 13.05 ± 0.16, P = 0.001) and diastolic BP (10 ± 0.7 vs. 9.1 ± 1, P = 0.031).

Conclusion: In our study, probiotic soy milk in comparing with soy milk did not have any beneficial effects on anthropometric measures in these patients. We need more clinical trial for confirming the effect of probiotic foods on anthropometric measure in diabetic patients. However, probiotic soy milk decreased systolic and diastolic BP significantly.

No MeSH data available.


Summary of patient flow
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4530661&req=5

f1-ARYA-11-074: Summary of patient flow

Mentions: This study was carried out from November 2013 to February 2014, and 48 diabetic patients participated in this study. Among individuals in the placebo group, 4 patients (need for antibiotic treatment, n = 1; changing drug, n = 2; poor compliance, n = 1) were excluded. Four patients in probiotic soy milk group were excluded (need for antibiotic treatment, n = 2; changing diet, n = 1; poor compliance, n = 1). Finally, 40 subjects (soy milk, n = 20; probiotic soy milk, n = 20) completed the trial (Figure 1).


The effect of probiotic soy milk and soy milk on anthropometric measures and blood pressure in patients with type II diabetes mellitus: A randomized double-blind clinical trial.

Hariri M, Salehi R, Feizi A, Mirlohi M, Kamali S, Ghiasvand R - ARYA Atheroscler (2015)

Summary of patient flow
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4530661&req=5

f1-ARYA-11-074: Summary of patient flow
Mentions: This study was carried out from November 2013 to February 2014, and 48 diabetic patients participated in this study. Among individuals in the placebo group, 4 patients (need for antibiotic treatment, n = 1; changing drug, n = 2; poor compliance, n = 1) were excluded. Four patients in probiotic soy milk group were excluded (need for antibiotic treatment, n = 2; changing diet, n = 1; poor compliance, n = 1). Finally, 40 subjects (soy milk, n = 20; probiotic soy milk, n = 20) completed the trial (Figure 1).

Bottom Line: Anthropometric and BP measurements were performed according to standard protocols.Although soy milk did not have any effect on BP, probiotic soymilk significantly decreased systolic (14.7 ± 0.48 vs. 13.05 ± 0.16, P = 0.001) and diastolic BP (10 ± 0.7 vs. 9.1 ± 1, P = 0.031).In our study, probiotic soy milk in comparing with soy milk did not have any beneficial effects on anthropometric measures in these patients.

View Article: PubMed Central - PubMed

Affiliation: Hypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.

ABSTRACT

Background: The objective of this clinical trial was to assess the effects of probiotic soy milk and soy milk on anthropometric measures and blood pressure (BP) in type 2 diabetic (T2D) patients.

Methods: A total of 40 patients with T2D, 35-68 years old, were assigned to two groups in this randomized, double-blind, controlled clinical trial. The patients in the intervention group consumed 200 ml/day of probiotic soy milk containing Lactobacillus planetarium A7 and those in control group consumed 200 ml/day of soy milk for 8 weeks. Anthropometric and BP measurements were performed according to standard protocols. For detecting within-group differences paired-sample t-tests was used and analysis of covariance was used for determining any differences between two groups. (The trial has been registered in the Iranian Registry of Clinical Trials, identifier: IRCT: IRCT201405265062N8).

Results: In this study, we failed to find any significant changes between probiotic soy milk and soy milk in term of body mass index (26.65 ± 0.68 vs. 26.33 ± 0.74, P = 0.300) and waist to hip ratio (1.49 ± 0.08 vs. 1.54 ± 0.1, P = 0.170). Although soy milk did not have any effect on BP, probiotic soymilk significantly decreased systolic (14.7 ± 0.48 vs. 13.05 ± 0.16, P = 0.001) and diastolic BP (10 ± 0.7 vs. 9.1 ± 1, P = 0.031).

Conclusion: In our study, probiotic soy milk in comparing with soy milk did not have any beneficial effects on anthropometric measures in these patients. We need more clinical trial for confirming the effect of probiotic foods on anthropometric measure in diabetic patients. However, probiotic soy milk decreased systolic and diastolic BP significantly.

No MeSH data available.