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Complementary Therapies for Idiopathic Hirsutism: Topical Licorice as Promising Option.

Faghihi G, Iraji F, Abtahi-Naeini B, Saffar B, Saffaei A, Pourazizi M, Aslani A, Nilforoushzadeh MA - Evid Based Complement Alternat Med (2015)

Bottom Line: To minimize the effects of confounding variables, the test was performed on two separate zones of patients' skin.In group B, they were 3.18 ± 1.75 for zone 1 and 2.49 ± 1.63 for zone 2.The difference in the mean number of terminal hairs was statistically significant between the two groups (p < 0.001), and there were no serious adverse reactions.

View Article: PubMed Central - PubMed

Affiliation: Skin Diseases and Leishmaniasis Research Center, Department of Dermatology, Isfahan University of Medical Sciences, Isfahan, Iran.

ABSTRACT
Hirsutism is one of the most prevalent health problems in women. The aim of the study was to compare the effect of 755 nm alexandrite hair removal laser with that of alexandrite laser plus topical licorice on the improvement of idiopathic hirsutism. A double-blind, randomized placebo-controlled study was performed on 90 female subjects. The patients were divided into two groups: alexandrite laser plus 15% licorice gel (group A) and placebo (group B). Each subject received one of both products over one side of the face, twice daily for 24 weeks on the hirsute locations. Each group underwent five sessions of alexandrite laser at 6-week intervals. To minimize the effects of confounding variables, the test was performed on two separate zones of patients' skin. The mean ± SD numbers of terminal hairs in group A were 7.05 ± 4.55 for zone 1 and 6.06 ± 3.70 for zone 2. In group B, they were 3.18 ± 1.75 for zone 1 and 2.49 ± 1.63 for zone 2. The difference in the mean number of terminal hairs was statistically significant between the two groups (p < 0.001), and there were no serious adverse reactions. The treatment of idiopathic hirsutism with 755 nm alexandrite laser plus topical licorice is more effective than alexandrite laser only.

No MeSH data available.


Related in: MedlinePlus

CONSORT flow diagram of the study.
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Related In: Results  -  Collection


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fig1: CONSORT flow diagram of the study.

Mentions: A double-blind, randomized placebo-controlled study was done to assess the efficacy of a 5-session alexandrite laser treatment and 24-week topical 15% licorice gel treatment on mild to moderate idiopathic hirsutism. The COSORT flow diagram of this study is shown in Figure 1.


Complementary Therapies for Idiopathic Hirsutism: Topical Licorice as Promising Option.

Faghihi G, Iraji F, Abtahi-Naeini B, Saffar B, Saffaei A, Pourazizi M, Aslani A, Nilforoushzadeh MA - Evid Based Complement Alternat Med (2015)

CONSORT flow diagram of the study.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4530245&req=5

fig1: CONSORT flow diagram of the study.
Mentions: A double-blind, randomized placebo-controlled study was done to assess the efficacy of a 5-session alexandrite laser treatment and 24-week topical 15% licorice gel treatment on mild to moderate idiopathic hirsutism. The COSORT flow diagram of this study is shown in Figure 1.

Bottom Line: To minimize the effects of confounding variables, the test was performed on two separate zones of patients' skin.In group B, they were 3.18 ± 1.75 for zone 1 and 2.49 ± 1.63 for zone 2.The difference in the mean number of terminal hairs was statistically significant between the two groups (p < 0.001), and there were no serious adverse reactions.

View Article: PubMed Central - PubMed

Affiliation: Skin Diseases and Leishmaniasis Research Center, Department of Dermatology, Isfahan University of Medical Sciences, Isfahan, Iran.

ABSTRACT
Hirsutism is one of the most prevalent health problems in women. The aim of the study was to compare the effect of 755 nm alexandrite hair removal laser with that of alexandrite laser plus topical licorice on the improvement of idiopathic hirsutism. A double-blind, randomized placebo-controlled study was performed on 90 female subjects. The patients were divided into two groups: alexandrite laser plus 15% licorice gel (group A) and placebo (group B). Each subject received one of both products over one side of the face, twice daily for 24 weeks on the hirsute locations. Each group underwent five sessions of alexandrite laser at 6-week intervals. To minimize the effects of confounding variables, the test was performed on two separate zones of patients' skin. The mean ± SD numbers of terminal hairs in group A were 7.05 ± 4.55 for zone 1 and 6.06 ± 3.70 for zone 2. In group B, they were 3.18 ± 1.75 for zone 1 and 2.49 ± 1.63 for zone 2. The difference in the mean number of terminal hairs was statistically significant between the two groups (p < 0.001), and there were no serious adverse reactions. The treatment of idiopathic hirsutism with 755 nm alexandrite laser plus topical licorice is more effective than alexandrite laser only.

No MeSH data available.


Related in: MedlinePlus