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Vocal Hoarseness and a Subglottic Mass: An Uncommon Diagnosis for a Common Complaint.

Rafizadeh S, Yoneda K, Zeki AA - J Investig Med High Impact Case Rep (2015)

Bottom Line: Symptoms may range from a completely silent condition to life-threatening respiratory failure and diagnosis is made based on radiological and bronchoscopic findings.Although the etiology has not been established, TPO can be familial and is sometimes associated with chronic inflammation, such as seen with rheumatic diseases.This case highlights the need for understanding TPO so that it can be differentiated from potentially serious conditions such as necrotizing granulomatous diseases, invasive infections, and cancer.

View Article: PubMed Central - PubMed

Affiliation: University of California, Davis Medical Center, Sacramento, CA, USA.

ABSTRACT
We report a patient with tracheopathia osteoplastica (TPO), a rare or perhaps underrecognized disorder, detected in approximately 1 in every 2000 to 5000 patients who undergo bronchoscopy. TPO is marked by proliferation of bony and cartilaginous spurs leading to airway stenosis. Multiple submucosal cartilaginous and osseous nodules can develop in the respiratory tract and may involve the entire trachea and mainstem bronchi. Symptoms may range from a completely silent condition to life-threatening respiratory failure and diagnosis is made based on radiological and bronchoscopic findings. Although the etiology has not been established, TPO can be familial and is sometimes associated with chronic inflammation, such as seen with rheumatic diseases. This case highlights the need for understanding TPO so that it can be differentiated from potentially serious conditions such as necrotizing granulomatous diseases, invasive infections, and cancer.

No MeSH data available.


Related in: MedlinePlus

The chest CT shows a subglottic mass and anterior tracheal wall thickening with some calcifications, circumscribed by the yellow line.
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fig2-2324709615587528: The chest CT shows a subglottic mass and anterior tracheal wall thickening with some calcifications, circumscribed by the yellow line.

Mentions: Physical exam did not reveal any head or neck lymphadenopathy or masses. There was no evidence of stridor. Lung exam showed scattered bilateral wheezing and rhonchi, but no crackles. Cranial nerve neurological exam was also without gross deficits. Laboratory data were unremarkable except for leukocytosis (16 100/µL) and chronic renal insufficiency (blood urea nitrogen 59 mg/dL, creatinine 3.3 mg/dL). Chest radiograph and computed tomography (CT) scan of the chest are shown in Figure 1 and Figure 2, respectively. Bronchoscopy findings are shown in Figure 3.


Vocal Hoarseness and a Subglottic Mass: An Uncommon Diagnosis for a Common Complaint.

Rafizadeh S, Yoneda K, Zeki AA - J Investig Med High Impact Case Rep (2015)

The chest CT shows a subglottic mass and anterior tracheal wall thickening with some calcifications, circumscribed by the yellow line.
© Copyright Policy - creative-commons
Related In: Results  -  Collection

License 1 - License 2 - License 3
Show All Figures
getmorefigures.php?uid=PMC4528869&req=5

fig2-2324709615587528: The chest CT shows a subglottic mass and anterior tracheal wall thickening with some calcifications, circumscribed by the yellow line.
Mentions: Physical exam did not reveal any head or neck lymphadenopathy or masses. There was no evidence of stridor. Lung exam showed scattered bilateral wheezing and rhonchi, but no crackles. Cranial nerve neurological exam was also without gross deficits. Laboratory data were unremarkable except for leukocytosis (16 100/µL) and chronic renal insufficiency (blood urea nitrogen 59 mg/dL, creatinine 3.3 mg/dL). Chest radiograph and computed tomography (CT) scan of the chest are shown in Figure 1 and Figure 2, respectively. Bronchoscopy findings are shown in Figure 3.

Bottom Line: Symptoms may range from a completely silent condition to life-threatening respiratory failure and diagnosis is made based on radiological and bronchoscopic findings.Although the etiology has not been established, TPO can be familial and is sometimes associated with chronic inflammation, such as seen with rheumatic diseases.This case highlights the need for understanding TPO so that it can be differentiated from potentially serious conditions such as necrotizing granulomatous diseases, invasive infections, and cancer.

View Article: PubMed Central - PubMed

Affiliation: University of California, Davis Medical Center, Sacramento, CA, USA.

ABSTRACT
We report a patient with tracheopathia osteoplastica (TPO), a rare or perhaps underrecognized disorder, detected in approximately 1 in every 2000 to 5000 patients who undergo bronchoscopy. TPO is marked by proliferation of bony and cartilaginous spurs leading to airway stenosis. Multiple submucosal cartilaginous and osseous nodules can develop in the respiratory tract and may involve the entire trachea and mainstem bronchi. Symptoms may range from a completely silent condition to life-threatening respiratory failure and diagnosis is made based on radiological and bronchoscopic findings. Although the etiology has not been established, TPO can be familial and is sometimes associated with chronic inflammation, such as seen with rheumatic diseases. This case highlights the need for understanding TPO so that it can be differentiated from potentially serious conditions such as necrotizing granulomatous diseases, invasive infections, and cancer.

No MeSH data available.


Related in: MedlinePlus