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Using Bayesian Multilevel Whole Genome Regression Models for Partial Pooling of Training Sets in Genomic Prediction.

Technow F, Totir LR - G3 (Bethesda) (2015)

Bottom Line: No pooling was superior; however, when populations were large.A simulation showed that no pooling is superior when differences in genetic effects among populations are large and partial pooling when they are intermediate.We conclude that partial pooling with multilevel models can maximize the potential of pooling by making optimal use of information in pooled training sets.

View Article: PubMed Central - PubMed

Affiliation: DuPont Pioneer, Johnston, Iowa 50131 Frank.Technow@pioneer.com.

No MeSH data available.


Related in: MedlinePlus

Graphic visualization of the multilevel model (A) and the conventional BayesA model (B).
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fig1: Graphic visualization of the multilevel model (A) and the conventional BayesA model (B).

Mentions: The hierarchical prior distribution setup will be explained next. A graphical display is shown in Figure 1A. The prior of wasFigure 1


Using Bayesian Multilevel Whole Genome Regression Models for Partial Pooling of Training Sets in Genomic Prediction.

Technow F, Totir LR - G3 (Bethesda) (2015)

Graphic visualization of the multilevel model (A) and the conventional BayesA model (B).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4528317&req=5

fig1: Graphic visualization of the multilevel model (A) and the conventional BayesA model (B).
Mentions: The hierarchical prior distribution setup will be explained next. A graphical display is shown in Figure 1A. The prior of wasFigure 1

Bottom Line: No pooling was superior; however, when populations were large.A simulation showed that no pooling is superior when differences in genetic effects among populations are large and partial pooling when they are intermediate.We conclude that partial pooling with multilevel models can maximize the potential of pooling by making optimal use of information in pooled training sets.

View Article: PubMed Central - PubMed

Affiliation: DuPont Pioneer, Johnston, Iowa 50131 Frank.Technow@pioneer.com.

No MeSH data available.


Related in: MedlinePlus