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Pentazocine-induced contractures: Dilemma in management.

Kumar D, Gupta A, Sharma VP, Yadav G, Singh A, Verma AK - Indian J Pharmacol (2015 Jul-Aug)

Bottom Line: Pentazocine is a commonly used synthetic opioid analgesic for moderate to severe pain secondary to various conditions.Complications of parenteral opioid abuse including localized ulcerations, abscess, indurations, and sclerosis are well-documented.We present a rare case of drug abuse due to pentazocine (Fortwin) in a 32-year-old female, who had severe myogenic contractures of her knee joints.

View Article: PubMed Central - PubMed

Affiliation: Department of Physical Medicine and Rehabilitation, King George Medical University, Lucknow, Uttar Pradesh, India.

ABSTRACT
Pentazocine is a commonly used synthetic opioid analgesic for moderate to severe pain secondary to various conditions. Complications of parenteral opioid abuse including localized ulcerations, abscess, indurations, and sclerosis are well-documented. We present a rare case of drug abuse due to pentazocine (Fortwin) in a 32-year-old female, who had severe myogenic contractures of her knee joints.

No MeSH data available.


Related in: MedlinePlus

Flexion contracture of both hip, knee, and ankle (front view)
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Figure 1: Flexion contracture of both hip, knee, and ankle (front view)

Mentions: On general examination, her cardiopulmonary and neurological examination showed no abnormality except stiffness of both knee and ankle joints. On local examination of both lower limbs, tone of musculature gave feeling of abnormal woody hardness with shining skin over thigh and calf muscles. Multiple small healed abscesses scars were seen. Active and passive movement restriction was observed in both knees and ankles. Her feet were in equinus; more severe on right side and few degrees (10–15°) of dorsiflexion was seen on either side but unable to come to neutral position. She was unable to squat and sit cross-legged. There was 60° flexion contracture at right knee joint and 80° at left knee joint. Tendoachillis was tight on both sides. Both hips showed secondary flexion deformities [Figure 1].


Pentazocine-induced contractures: Dilemma in management.

Kumar D, Gupta A, Sharma VP, Yadav G, Singh A, Verma AK - Indian J Pharmacol (2015 Jul-Aug)

Flexion contracture of both hip, knee, and ankle (front view)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4527072&req=5

Figure 1: Flexion contracture of both hip, knee, and ankle (front view)
Mentions: On general examination, her cardiopulmonary and neurological examination showed no abnormality except stiffness of both knee and ankle joints. On local examination of both lower limbs, tone of musculature gave feeling of abnormal woody hardness with shining skin over thigh and calf muscles. Multiple small healed abscesses scars were seen. Active and passive movement restriction was observed in both knees and ankles. Her feet were in equinus; more severe on right side and few degrees (10–15°) of dorsiflexion was seen on either side but unable to come to neutral position. She was unable to squat and sit cross-legged. There was 60° flexion contracture at right knee joint and 80° at left knee joint. Tendoachillis was tight on both sides. Both hips showed secondary flexion deformities [Figure 1].

Bottom Line: Pentazocine is a commonly used synthetic opioid analgesic for moderate to severe pain secondary to various conditions.Complications of parenteral opioid abuse including localized ulcerations, abscess, indurations, and sclerosis are well-documented.We present a rare case of drug abuse due to pentazocine (Fortwin) in a 32-year-old female, who had severe myogenic contractures of her knee joints.

View Article: PubMed Central - PubMed

Affiliation: Department of Physical Medicine and Rehabilitation, King George Medical University, Lucknow, Uttar Pradesh, India.

ABSTRACT
Pentazocine is a commonly used synthetic opioid analgesic for moderate to severe pain secondary to various conditions. Complications of parenteral opioid abuse including localized ulcerations, abscess, indurations, and sclerosis are well-documented. We present a rare case of drug abuse due to pentazocine (Fortwin) in a 32-year-old female, who had severe myogenic contractures of her knee joints.

No MeSH data available.


Related in: MedlinePlus