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Meta-analysis for psychiatric research using free software R.

Chen DG - Shanghai Arch Psychiatry (2015)

Bottom Line: This paper provides a brief overview of meta-analysis (MA) with emphasis on classical fixedeffects and random-effects MA models.It illustrates the application of MA models with the open-source software R using publicly available data from five studies on lamotrigine to treat bipolar depression and finds that meta-analysis identifies a statistically significant advantage of lamotrigine over placebo that was not evident in the individual studies.Abstract available from the publisher.

View Article: PubMed Central - PubMed

Affiliation: School of Social Work, University of North Carolina at Chapel Hill, Chapel Hill, United States.

ABSTRACT

Summary: This paper provides a brief overview of meta-analysis (MA) with emphasis on classical fixedeffects and random-effects MA models. It illustrates the application of MA models with the open-source software R using publicly available data from five studies on lamotrigine to treat bipolar depression and finds that meta-analysis identifies a statistically significant advantage of lamotrigine over placebo that was not evident in the individual studies.

No MeSH data available.


Related in: MedlinePlus

Forest plot for meta-analysis of five lamotrigine clinical trials
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sap-27-03-195-g002.tif: Forest plot for meta-analysis of five lamotrigine clinical trials


Meta-analysis for psychiatric research using free software R.

Chen DG - Shanghai Arch Psychiatry (2015)

Forest plot for meta-analysis of five lamotrigine clinical trials
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4526834&req=5

sap-27-03-195-g002.tif: Forest plot for meta-analysis of five lamotrigine clinical trials
Bottom Line: This paper provides a brief overview of meta-analysis (MA) with emphasis on classical fixedeffects and random-effects MA models.It illustrates the application of MA models with the open-source software R using publicly available data from five studies on lamotrigine to treat bipolar depression and finds that meta-analysis identifies a statistically significant advantage of lamotrigine over placebo that was not evident in the individual studies.Abstract available from the publisher.

View Article: PubMed Central - PubMed

Affiliation: School of Social Work, University of North Carolina at Chapel Hill, Chapel Hill, United States.

ABSTRACT

Summary: This paper provides a brief overview of meta-analysis (MA) with emphasis on classical fixedeffects and random-effects MA models. It illustrates the application of MA models with the open-source software R using publicly available data from five studies on lamotrigine to treat bipolar depression and finds that meta-analysis identifies a statistically significant advantage of lamotrigine over placebo that was not evident in the individual studies.

No MeSH data available.


Related in: MedlinePlus