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Lower dorsal striatum activation in association with neuroticism during the acceptance of unfair offers.

Servaas MN, Aleman A, Marsman JB, Renken RJ, Riese H, Ormel J - Cogn Affect Behav Neurosci (2015)

Bottom Line: Furthermore, we found more activation in parietal and temporal regions for the two most common decisions (fair accept and unfair reject), involving areas related to perceptual decision-making.High compared to low neurotic individuals did not show differential activation patterns during the proposal of unfair offers; however, they did show lower activation in the right dorsal striatum (putamen) during the acceptance of unfair offers.In conclusion, the findings suggest that both high and low neurotic individuals recruit brain regions signaling social norm violations in response to unfair offers.

View Article: PubMed Central - PubMed

Affiliation: Neuroimaging Center, Department of Neuroscience, University Medical Center Groningen, University of Groningen, PO Box 196, 9700 AD, Groningen, The Netherlands, m.n.servaas@umcg.nl.

ABSTRACT
Unfair treatment may evoke more negative emotions in individuals scoring higher on neuroticism, thereby possibly impacting their decision-making in these situations. To investigate the neural basis of social decision-making in these individuals, we examined interpersonal reactions to unfairness in the Ultimatum Game (UG). We measured brain activation with fMRI in 120 participants selected based on their neuroticism score, while they made decisions to accept or reject proposals that were either fair or unfair. The anterior insula and anterior cingulate cortex were more activated during the processing of unfair offers, consistent with prior UG studies. Furthermore, we found more activation in parietal and temporal regions for the two most common decisions (fair accept and unfair reject), involving areas related to perceptual decision-making. Conversely, during the decision to accept unfair offers, individuals recruited more frontal regions previously associated with decision-making and the implementation of reappraisal in the UG. High compared to low neurotic individuals did not show differential activation patterns during the proposal of unfair offers; however, they did show lower activation in the right dorsal striatum (putamen) during the acceptance of unfair offers. This brain region has been involved in the formation of stimulus-action-reward associations and motivation/arousal. In conclusion, the findings suggest that both high and low neurotic individuals recruit brain regions signaling social norm violations in response to unfair offers. However, when it comes to decision-making, it seems that neural circuitry related to reward and motivation is altered in individuals scoring higher on neuroticism, when accepting an unfair offer.

No MeSH data available.


Related in: MedlinePlus

Interaction effect between neuroticism and the decision condition. Activation in the dorsal striatum correlated negatively with neuroticism for the contrast (decision unfair accepted > decision fair accepted) (red) and (decision unfair accepted > decision unfair rejected) (blue). The color purple indicates overlap between the two contrasts
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Fig3: Interaction effect between neuroticism and the decision condition. Activation in the dorsal striatum correlated negatively with neuroticism for the contrast (decision unfair accepted > decision fair accepted) (red) and (decision unfair accepted > decision unfair rejected) (blue). The color purple indicates overlap between the two contrasts

Mentions: Brain regions were identified that correlated with neuroticism for abovementioned contrasts. Neuroticism was associated with lower activation in (i) the dorsal striatum (putamen) and vermis/cerebellum for the contrast (unfair accepted > fair accepted) and (ii) the dorsal striatum (putamen) for the contrast (unfair accepted > unfair rejected; see Table 4 and Fig. 3 for the results). No significant results were found for the other contrasts. When the results were visualized in a scatter plot, we observed a negative correlation between neuroticism and activation in the dorsal striatum for the condition unfair accepted (unfair accepted > fair accepted r = -0.40; unfair accepted > unfair rejected r = -0.48), while a weak correlation was observed for the conditions fair accepted (r = 0.04) and unfair rejected (r = 0.14; see Appendix D for scatter plots). For a complete overview, results for the interaction effect between neuroticism and the proposal (thresholded at p < .05 FWE cluster-level extent using an initial threshold of p < .01 uncorrected), decision (thresholded at p < .05 FWE cluster-level extent using an initial threshold of p < .01 uncorrected and a cluster size of k > 316) and outcome (thresholded at p < .05 FWE cluster-level extent using an initial threshold of p < .001 and p < .01 uncorrected and a cluster size of k > 102 and k > 316, respectively) condition can be found in Appendix E, Table 6.Fig. 3


Lower dorsal striatum activation in association with neuroticism during the acceptance of unfair offers.

Servaas MN, Aleman A, Marsman JB, Renken RJ, Riese H, Ormel J - Cogn Affect Behav Neurosci (2015)

Interaction effect between neuroticism and the decision condition. Activation in the dorsal striatum correlated negatively with neuroticism for the contrast (decision unfair accepted > decision fair accepted) (red) and (decision unfair accepted > decision unfair rejected) (blue). The color purple indicates overlap between the two contrasts
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

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getmorefigures.php?uid=PMC4526587&req=5

Fig3: Interaction effect between neuroticism and the decision condition. Activation in the dorsal striatum correlated negatively with neuroticism for the contrast (decision unfair accepted > decision fair accepted) (red) and (decision unfair accepted > decision unfair rejected) (blue). The color purple indicates overlap between the two contrasts
Mentions: Brain regions were identified that correlated with neuroticism for abovementioned contrasts. Neuroticism was associated with lower activation in (i) the dorsal striatum (putamen) and vermis/cerebellum for the contrast (unfair accepted > fair accepted) and (ii) the dorsal striatum (putamen) for the contrast (unfair accepted > unfair rejected; see Table 4 and Fig. 3 for the results). No significant results were found for the other contrasts. When the results were visualized in a scatter plot, we observed a negative correlation between neuroticism and activation in the dorsal striatum for the condition unfair accepted (unfair accepted > fair accepted r = -0.40; unfair accepted > unfair rejected r = -0.48), while a weak correlation was observed for the conditions fair accepted (r = 0.04) and unfair rejected (r = 0.14; see Appendix D for scatter plots). For a complete overview, results for the interaction effect between neuroticism and the proposal (thresholded at p < .05 FWE cluster-level extent using an initial threshold of p < .01 uncorrected), decision (thresholded at p < .05 FWE cluster-level extent using an initial threshold of p < .01 uncorrected and a cluster size of k > 316) and outcome (thresholded at p < .05 FWE cluster-level extent using an initial threshold of p < .001 and p < .01 uncorrected and a cluster size of k > 102 and k > 316, respectively) condition can be found in Appendix E, Table 6.Fig. 3

Bottom Line: Furthermore, we found more activation in parietal and temporal regions for the two most common decisions (fair accept and unfair reject), involving areas related to perceptual decision-making.High compared to low neurotic individuals did not show differential activation patterns during the proposal of unfair offers; however, they did show lower activation in the right dorsal striatum (putamen) during the acceptance of unfair offers.In conclusion, the findings suggest that both high and low neurotic individuals recruit brain regions signaling social norm violations in response to unfair offers.

View Article: PubMed Central - PubMed

Affiliation: Neuroimaging Center, Department of Neuroscience, University Medical Center Groningen, University of Groningen, PO Box 196, 9700 AD, Groningen, The Netherlands, m.n.servaas@umcg.nl.

ABSTRACT
Unfair treatment may evoke more negative emotions in individuals scoring higher on neuroticism, thereby possibly impacting their decision-making in these situations. To investigate the neural basis of social decision-making in these individuals, we examined interpersonal reactions to unfairness in the Ultimatum Game (UG). We measured brain activation with fMRI in 120 participants selected based on their neuroticism score, while they made decisions to accept or reject proposals that were either fair or unfair. The anterior insula and anterior cingulate cortex were more activated during the processing of unfair offers, consistent with prior UG studies. Furthermore, we found more activation in parietal and temporal regions for the two most common decisions (fair accept and unfair reject), involving areas related to perceptual decision-making. Conversely, during the decision to accept unfair offers, individuals recruited more frontal regions previously associated with decision-making and the implementation of reappraisal in the UG. High compared to low neurotic individuals did not show differential activation patterns during the proposal of unfair offers; however, they did show lower activation in the right dorsal striatum (putamen) during the acceptance of unfair offers. This brain region has been involved in the formation of stimulus-action-reward associations and motivation/arousal. In conclusion, the findings suggest that both high and low neurotic individuals recruit brain regions signaling social norm violations in response to unfair offers. However, when it comes to decision-making, it seems that neural circuitry related to reward and motivation is altered in individuals scoring higher on neuroticism, when accepting an unfair offer.

No MeSH data available.


Related in: MedlinePlus