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Hydrothermal Synthesis and Biocompatibility Study of Highly Crystalline Carbonated Hydroxyapatite Nanorods.

Xue C, Chen Y, Huang Y, Zhu P - Nanoscale Res Lett (2015)

Bottom Line: Highly crystalline carbonated hydroxyapatite (CHA) nanorods with different carbonate contents were synthesized by a novel hydrothermal method.The biocompatibility of synthesized CHA nanorods was evaluated by cell viability and alkaline phosphatase (ALP) activity of MG-63 cell line.The biocompatibility evaluation results show that these CHA nanorods are biologically active apatites and potentially promising bone-substitute biomaterials for orthopedic application.

View Article: PubMed Central - PubMed

Affiliation: School of Chemistry and Chemical Engineering, Yangzhou University, Jiangsu, 225009, China.

ABSTRACT
Highly crystalline carbonated hydroxyapatite (CHA) nanorods with different carbonate contents were synthesized by a novel hydrothermal method. The crystallinity and chemical structure of synthesized nanorods were studied by Fourier transform infrared spectroscopy (FTIR), X-ray photo-electronic spectroscopy (XPS), X-ray diffraction (XRD), Raman spectroscopy, and transmission electron microscopy (TEM). The biocompatibility of synthesized CHA nanorods was evaluated by cell viability and alkaline phosphatase (ALP) activity of MG-63 cell line. The biocompatibility evaluation results show that these CHA nanorods are biologically active apatites and potentially promising bone-substitute biomaterials for orthopedic application.

No MeSH data available.


Related in: MedlinePlus

XPS characterization of synthesized nanorods
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Fig3: XPS characterization of synthesized nanorods

Mentions: The XPS spectra of CHA nanorods containing different carbonate levels are shown in Fig. 3. One peak corresponding to C 1s was revealed at 285.1 eV, indicating that different amounts of carbonate ions have been successfully incorporated into the apatite lattice structure. The carbonate contents in HA, CHA1, CHA2, CHA3 are measured as 0.9, 1.54, 2.26, 5.22 wt %, respectively.Fig. 3


Hydrothermal Synthesis and Biocompatibility Study of Highly Crystalline Carbonated Hydroxyapatite Nanorods.

Xue C, Chen Y, Huang Y, Zhu P - Nanoscale Res Lett (2015)

XPS characterization of synthesized nanorods
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4526508&req=5

Fig3: XPS characterization of synthesized nanorods
Mentions: The XPS spectra of CHA nanorods containing different carbonate levels are shown in Fig. 3. One peak corresponding to C 1s was revealed at 285.1 eV, indicating that different amounts of carbonate ions have been successfully incorporated into the apatite lattice structure. The carbonate contents in HA, CHA1, CHA2, CHA3 are measured as 0.9, 1.54, 2.26, 5.22 wt %, respectively.Fig. 3

Bottom Line: Highly crystalline carbonated hydroxyapatite (CHA) nanorods with different carbonate contents were synthesized by a novel hydrothermal method.The biocompatibility of synthesized CHA nanorods was evaluated by cell viability and alkaline phosphatase (ALP) activity of MG-63 cell line.The biocompatibility evaluation results show that these CHA nanorods are biologically active apatites and potentially promising bone-substitute biomaterials for orthopedic application.

View Article: PubMed Central - PubMed

Affiliation: School of Chemistry and Chemical Engineering, Yangzhou University, Jiangsu, 225009, China.

ABSTRACT
Highly crystalline carbonated hydroxyapatite (CHA) nanorods with different carbonate contents were synthesized by a novel hydrothermal method. The crystallinity and chemical structure of synthesized nanorods were studied by Fourier transform infrared spectroscopy (FTIR), X-ray photo-electronic spectroscopy (XPS), X-ray diffraction (XRD), Raman spectroscopy, and transmission electron microscopy (TEM). The biocompatibility of synthesized CHA nanorods was evaluated by cell viability and alkaline phosphatase (ALP) activity of MG-63 cell line. The biocompatibility evaluation results show that these CHA nanorods are biologically active apatites and potentially promising bone-substitute biomaterials for orthopedic application.

No MeSH data available.


Related in: MedlinePlus