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Hydrothermal Synthesis and Biocompatibility Study of Highly Crystalline Carbonated Hydroxyapatite Nanorods.

Xue C, Chen Y, Huang Y, Zhu P - Nanoscale Res Lett (2015)

Bottom Line: Highly crystalline carbonated hydroxyapatite (CHA) nanorods with different carbonate contents were synthesized by a novel hydrothermal method.The biocompatibility of synthesized CHA nanorods was evaluated by cell viability and alkaline phosphatase (ALP) activity of MG-63 cell line.The biocompatibility evaluation results show that these CHA nanorods are biologically active apatites and potentially promising bone-substitute biomaterials for orthopedic application.

View Article: PubMed Central - PubMed

Affiliation: School of Chemistry and Chemical Engineering, Yangzhou University, Jiangsu, 225009, China.

ABSTRACT
Highly crystalline carbonated hydroxyapatite (CHA) nanorods with different carbonate contents were synthesized by a novel hydrothermal method. The crystallinity and chemical structure of synthesized nanorods were studied by Fourier transform infrared spectroscopy (FTIR), X-ray photo-electronic spectroscopy (XPS), X-ray diffraction (XRD), Raman spectroscopy, and transmission electron microscopy (TEM). The biocompatibility of synthesized CHA nanorods was evaluated by cell viability and alkaline phosphatase (ALP) activity of MG-63 cell line. The biocompatibility evaluation results show that these CHA nanorods are biologically active apatites and potentially promising bone-substitute biomaterials for orthopedic application.

No MeSH data available.


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FTIR characterization of synthesized nanorods
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Fig2: FTIR characterization of synthesized nanorods

Mentions: Figure 2 shows the FTIR spectra of synthesized CHA nanorods. The broad and characteristic bands at 1023 and 562 cm−1 are assigned to the PO43− ions [24]. Three peaks at 1093, 1023, and 960 cm−1 should be attributed to υ1 and υ3 phosphate modes, and 601 and 562 cm−1 are attributed to υ4 phosphate modes. The antisymmetric stretching vibration of C-O (υ3) in the region 1500–1400 cm−1 indicates that different contents of CO32− have been doped in synthesized nanorods. The υ2 vibration of CO32− at 872 cm−1 and υ3 vibration of carbonate confirm the B-type substitution in all CHA nanorods [3].Fig. 2


Hydrothermal Synthesis and Biocompatibility Study of Highly Crystalline Carbonated Hydroxyapatite Nanorods.

Xue C, Chen Y, Huang Y, Zhu P - Nanoscale Res Lett (2015)

FTIR characterization of synthesized nanorods
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4526508&req=5

Fig2: FTIR characterization of synthesized nanorods
Mentions: Figure 2 shows the FTIR spectra of synthesized CHA nanorods. The broad and characteristic bands at 1023 and 562 cm−1 are assigned to the PO43− ions [24]. Three peaks at 1093, 1023, and 960 cm−1 should be attributed to υ1 and υ3 phosphate modes, and 601 and 562 cm−1 are attributed to υ4 phosphate modes. The antisymmetric stretching vibration of C-O (υ3) in the region 1500–1400 cm−1 indicates that different contents of CO32− have been doped in synthesized nanorods. The υ2 vibration of CO32− at 872 cm−1 and υ3 vibration of carbonate confirm the B-type substitution in all CHA nanorods [3].Fig. 2

Bottom Line: Highly crystalline carbonated hydroxyapatite (CHA) nanorods with different carbonate contents were synthesized by a novel hydrothermal method.The biocompatibility of synthesized CHA nanorods was evaluated by cell viability and alkaline phosphatase (ALP) activity of MG-63 cell line.The biocompatibility evaluation results show that these CHA nanorods are biologically active apatites and potentially promising bone-substitute biomaterials for orthopedic application.

View Article: PubMed Central - PubMed

Affiliation: School of Chemistry and Chemical Engineering, Yangzhou University, Jiangsu, 225009, China.

ABSTRACT
Highly crystalline carbonated hydroxyapatite (CHA) nanorods with different carbonate contents were synthesized by a novel hydrothermal method. The crystallinity and chemical structure of synthesized nanorods were studied by Fourier transform infrared spectroscopy (FTIR), X-ray photo-electronic spectroscopy (XPS), X-ray diffraction (XRD), Raman spectroscopy, and transmission electron microscopy (TEM). The biocompatibility of synthesized CHA nanorods was evaluated by cell viability and alkaline phosphatase (ALP) activity of MG-63 cell line. The biocompatibility evaluation results show that these CHA nanorods are biologically active apatites and potentially promising bone-substitute biomaterials for orthopedic application.

No MeSH data available.


Related in: MedlinePlus