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Radiologic Evaluation of Compressive Osseointegration for the Fixation of Reconstruction Prostheses after Tumor Resection.

Lazarov M, De Bo T, Poffyn B, Sys G - Biomed Res Int (2015)

Bottom Line: There were no significant differences between the two cohorts.Group 2, which was significantly younger than group 1 (p < 0.001), presented a delayed initial rate of bone formation and reached stage 1 at 6 months instead of 3 months like group 1.Despite the fact that the staging fails to demonstrate a statistical difference, it is rather simple and can be used for future studies.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopaedics, University Hospital Ghent, De Pintelaan 185, 9000 Ghent, Belgium.

ABSTRACT

Objective: In pursuance of thoroughly understanding and facilitating the evaluation of the radiological changes in the preloaded bone by Compliant Pre-Stress osseointegration (Compress Biomet, Warsaw, Indiana) a new staging method was created depicting four stages.

Methods: Two cohorts (10 and 17 patients resp., not-receiving and receiving chemotherapy) were compared in terms of progression of osseointegration. Based on the changes at the bone-metal interface seen on röntgenorgrams four stages were defined: stage 0: immediate postoperative status, no ingrowth, or noncalcified callus; stage 1: early mineralization, calcified callus; stage 2: mature mineralization; and stage 3: hypertrophy at the level of the pins.

Results: There were no significant differences between the two cohorts. Group 2, which was significantly younger than group 1 (p < 0.001), presented a delayed initial rate of bone formation and reached stage 1 at 6 months instead of 3 months like group 1. The children from the group 2 demonstrated a visible rebound ingrowth.

Conclusion: Despite the fact that the staging fails to demonstrate a statistical difference, it is rather simple and can be used for future studies.

No MeSH data available.


Related in: MedlinePlus

Heterotopic ossification seen at 6 months postop.
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Related In: Results  -  Collection


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fig3: Heterotopic ossification seen at 6 months postop.

Mentions: In our institution ultrasound is used for the local follow-up aiming at detection of local tumor recurrence in the proximity of large prosthetic implants. During the early stages an intense hypervascular aspect at the bone-prosthetic interface is observed. This phenomenon is also very distinct in a Technetium bone scan. Furthermore, callus formation should not be confused with heterotopic ossification, as seen in Figure 3.


Radiologic Evaluation of Compressive Osseointegration for the Fixation of Reconstruction Prostheses after Tumor Resection.

Lazarov M, De Bo T, Poffyn B, Sys G - Biomed Res Int (2015)

Heterotopic ossification seen at 6 months postop.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4525760&req=5

fig3: Heterotopic ossification seen at 6 months postop.
Mentions: In our institution ultrasound is used for the local follow-up aiming at detection of local tumor recurrence in the proximity of large prosthetic implants. During the early stages an intense hypervascular aspect at the bone-prosthetic interface is observed. This phenomenon is also very distinct in a Technetium bone scan. Furthermore, callus formation should not be confused with heterotopic ossification, as seen in Figure 3.

Bottom Line: There were no significant differences between the two cohorts.Group 2, which was significantly younger than group 1 (p < 0.001), presented a delayed initial rate of bone formation and reached stage 1 at 6 months instead of 3 months like group 1.Despite the fact that the staging fails to demonstrate a statistical difference, it is rather simple and can be used for future studies.

View Article: PubMed Central - PubMed

Affiliation: Department of Orthopaedics, University Hospital Ghent, De Pintelaan 185, 9000 Ghent, Belgium.

ABSTRACT

Objective: In pursuance of thoroughly understanding and facilitating the evaluation of the radiological changes in the preloaded bone by Compliant Pre-Stress osseointegration (Compress Biomet, Warsaw, Indiana) a new staging method was created depicting four stages.

Methods: Two cohorts (10 and 17 patients resp., not-receiving and receiving chemotherapy) were compared in terms of progression of osseointegration. Based on the changes at the bone-metal interface seen on röntgenorgrams four stages were defined: stage 0: immediate postoperative status, no ingrowth, or noncalcified callus; stage 1: early mineralization, calcified callus; stage 2: mature mineralization; and stage 3: hypertrophy at the level of the pins.

Results: There were no significant differences between the two cohorts. Group 2, which was significantly younger than group 1 (p < 0.001), presented a delayed initial rate of bone formation and reached stage 1 at 6 months instead of 3 months like group 1. The children from the group 2 demonstrated a visible rebound ingrowth.

Conclusion: Despite the fact that the staging fails to demonstrate a statistical difference, it is rather simple and can be used for future studies.

No MeSH data available.


Related in: MedlinePlus