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Primary Peritoneal Mesothelioma Resulting in Small Bowel Obstruction: A Case Report and Review of Literature.

Frontario SC, Loveitt A, Goldenberg-Sandau A, Liu J, Roy D, Cohen LW - Am J Case Rep (2015)

Bottom Line: The patient had multiple risk factors with asbestos exposure and prior therapeutic radiation.However, there are other non-asbestos etiologies.Small bowel obstruction often is a late-presenting symptom of widespread tumor burden.

View Article: PubMed Central - PubMed

Affiliation: Department of Surgery, Rowan University School of Osteopathic Medicine, Stratford, NJ, USA.

ABSTRACT

Background: Peritoneal mesothelioma is a rare malignancy that affects the serosal surfaces of the peritoneum. The peritoneum is the second most common site of mesothelium affected following the pleura. The aggressive nature and vague presentation pose many obstacles in not only diagnosis but also the treatment of patients with this disease.

Case report: We present a case of a 76-year-old woman who presented with small bowel obstruction secondary to carcinomatosis secondary to primary peritoneal mesothelioma. The patient had multiple risk factors with asbestos exposure and prior therapeutic radiation.

Conclusions: We discuss the highly varied and elusive presentation of peritoneal mesothelioma. Cumulative asbestos exposure, either directly or indirectly, remains the leading cause of mesothelioma. However, there are other non-asbestos etiologies. Small bowel obstruction often is a late-presenting symptom of widespread tumor burden. A concise review of the current diagnostic and surgical treatment of primary peritoneal mesothelioma demonstrates that early diagnosis and implementation remains vital.

No MeSH data available.


Related in: MedlinePlus

Computed tomography scan of the abdomen with dilated loops of small bowel and retained contrast. There is also thickened wall of the lower rectum and ascitic fluid throughout.
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f1-amjcaserep-16-496: Computed tomography scan of the abdomen with dilated loops of small bowel and retained contrast. There is also thickened wall of the lower rectum and ascitic fluid throughout.

Mentions: Pertinent laboratory studies included sodium of 125 mEq/L, hemoglobin of 9 g/dL, white blood cell count of 15.4×109/L, as well as a platelet count of 676×109/L. Tumor markers included a CA 125 of 4094.4 U/mL and CEA of <0.50ng/mL. A CT of the abdomen and pelvis revealed ascites, stomach and small bowel wall thickening, and dilation of multiple small bowel loops (Figure 1).


Primary Peritoneal Mesothelioma Resulting in Small Bowel Obstruction: A Case Report and Review of Literature.

Frontario SC, Loveitt A, Goldenberg-Sandau A, Liu J, Roy D, Cohen LW - Am J Case Rep (2015)

Computed tomography scan of the abdomen with dilated loops of small bowel and retained contrast. There is also thickened wall of the lower rectum and ascitic fluid throughout.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4525679&req=5

f1-amjcaserep-16-496: Computed tomography scan of the abdomen with dilated loops of small bowel and retained contrast. There is also thickened wall of the lower rectum and ascitic fluid throughout.
Mentions: Pertinent laboratory studies included sodium of 125 mEq/L, hemoglobin of 9 g/dL, white blood cell count of 15.4×109/L, as well as a platelet count of 676×109/L. Tumor markers included a CA 125 of 4094.4 U/mL and CEA of <0.50ng/mL. A CT of the abdomen and pelvis revealed ascites, stomach and small bowel wall thickening, and dilation of multiple small bowel loops (Figure 1).

Bottom Line: The patient had multiple risk factors with asbestos exposure and prior therapeutic radiation.However, there are other non-asbestos etiologies.Small bowel obstruction often is a late-presenting symptom of widespread tumor burden.

View Article: PubMed Central - PubMed

Affiliation: Department of Surgery, Rowan University School of Osteopathic Medicine, Stratford, NJ, USA.

ABSTRACT

Background: Peritoneal mesothelioma is a rare malignancy that affects the serosal surfaces of the peritoneum. The peritoneum is the second most common site of mesothelium affected following the pleura. The aggressive nature and vague presentation pose many obstacles in not only diagnosis but also the treatment of patients with this disease.

Case report: We present a case of a 76-year-old woman who presented with small bowel obstruction secondary to carcinomatosis secondary to primary peritoneal mesothelioma. The patient had multiple risk factors with asbestos exposure and prior therapeutic radiation.

Conclusions: We discuss the highly varied and elusive presentation of peritoneal mesothelioma. Cumulative asbestos exposure, either directly or indirectly, remains the leading cause of mesothelioma. However, there are other non-asbestos etiologies. Small bowel obstruction often is a late-presenting symptom of widespread tumor burden. A concise review of the current diagnostic and surgical treatment of primary peritoneal mesothelioma demonstrates that early diagnosis and implementation remains vital.

No MeSH data available.


Related in: MedlinePlus