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A Case of Giant Uterine Lipoleiomyoma Simulating Malignancy.

Karaman E, Çim N, Bulut G, Elçi G, Andıç E, Tekin M, Kolusarı A - Case Rep Obstet Gynecol (2015)

Bottom Line: On operation, total abdominal hysterectomy with a pedunculated mass of size 30 × 23 × 12 cm and weighing 5.4 kg and bilateral salpingo-oophorectomy were performed.Discussion.Conclusion.

View Article: PubMed Central - PubMed

Affiliation: Department of Obstetrics and Gynecology, Yuzuncu Yil University, 65000 Van, Turkey.

ABSTRACT
Introduction. Uterine leiomyoma is the most common benign pathology in women and lipoleiomyoma is an extremely rare and specific type of leiomyoma. Here, we report an unusual case of giant pedunculated subserous lipoleiomyoma misdiagnosed preoperatively as leiomyosarcoma. Case. A 45-year-old woman admitted to our gynecology outpatient clinic for complaints of abdominal distention, tiredness, and pelvic pain for the last 6 months. Sonography and abdominal magnetic resonance imaging (MRI) showed a giant semisolid mass that filled whole abdominal cavity from pelvis to subdiaphragmatic area. A primary diagnosis of uterine sarcoma or ovarian malignancy was made. On operation, total abdominal hysterectomy with a pedunculated mass of size 30 × 23 × 12 cm and weighing 5.4 kg and bilateral salpingo-oophorectomy were performed. The histopathology revealed a lipoleiomyoma with extensive cystic and fatty degeneration without any malignancy. Discussion. The diagnosis of leiomyoma is done usually with pelvic ultrasound but sometimes it is difficult to reach a correct diagnosis especially in cases of giant and pedunculated lipoleiomyoma that included fatty tissue which may mimick malignancy. Conclusion. Subserous pedunculated giant lipoleiomyoma should be kept in mind in the differential diagnosis of leiomyosarcoma or ovarian malignancy.

No MeSH data available.


Related in: MedlinePlus

The figure shows spindle-shaped smooth muscle cell proliferation admixed with mature adipocytes (arrow) (HE&40).
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fig4: The figure shows spindle-shaped smooth muscle cell proliferation admixed with mature adipocytes (arrow) (HE&40).

Mentions: Macroscopically, pathologic examination revealed a multilobulated solid mass measuring 32 × 23 × 12 cm showing the appearance of leiomyoma. The microscopic examination showed lipoleiomyoma of uterus with extensive cystic and fatty content as admixed with mature adipocytes without histologic signs of malignancy (Figure 4). Both ovaries and endometrial cytology were detected to be benign as normal ovary and proliferative endometrium.


A Case of Giant Uterine Lipoleiomyoma Simulating Malignancy.

Karaman E, Çim N, Bulut G, Elçi G, Andıç E, Tekin M, Kolusarı A - Case Rep Obstet Gynecol (2015)

The figure shows spindle-shaped smooth muscle cell proliferation admixed with mature adipocytes (arrow) (HE&40).
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4525463&req=5

fig4: The figure shows spindle-shaped smooth muscle cell proliferation admixed with mature adipocytes (arrow) (HE&40).
Mentions: Macroscopically, pathologic examination revealed a multilobulated solid mass measuring 32 × 23 × 12 cm showing the appearance of leiomyoma. The microscopic examination showed lipoleiomyoma of uterus with extensive cystic and fatty content as admixed with mature adipocytes without histologic signs of malignancy (Figure 4). Both ovaries and endometrial cytology were detected to be benign as normal ovary and proliferative endometrium.

Bottom Line: On operation, total abdominal hysterectomy with a pedunculated mass of size 30 × 23 × 12 cm and weighing 5.4 kg and bilateral salpingo-oophorectomy were performed.Discussion.Conclusion.

View Article: PubMed Central - PubMed

Affiliation: Department of Obstetrics and Gynecology, Yuzuncu Yil University, 65000 Van, Turkey.

ABSTRACT
Introduction. Uterine leiomyoma is the most common benign pathology in women and lipoleiomyoma is an extremely rare and specific type of leiomyoma. Here, we report an unusual case of giant pedunculated subserous lipoleiomyoma misdiagnosed preoperatively as leiomyosarcoma. Case. A 45-year-old woman admitted to our gynecology outpatient clinic for complaints of abdominal distention, tiredness, and pelvic pain for the last 6 months. Sonography and abdominal magnetic resonance imaging (MRI) showed a giant semisolid mass that filled whole abdominal cavity from pelvis to subdiaphragmatic area. A primary diagnosis of uterine sarcoma or ovarian malignancy was made. On operation, total abdominal hysterectomy with a pedunculated mass of size 30 × 23 × 12 cm and weighing 5.4 kg and bilateral salpingo-oophorectomy were performed. The histopathology revealed a lipoleiomyoma with extensive cystic and fatty degeneration without any malignancy. Discussion. The diagnosis of leiomyoma is done usually with pelvic ultrasound but sometimes it is difficult to reach a correct diagnosis especially in cases of giant and pedunculated lipoleiomyoma that included fatty tissue which may mimick malignancy. Conclusion. Subserous pedunculated giant lipoleiomyoma should be kept in mind in the differential diagnosis of leiomyosarcoma or ovarian malignancy.

No MeSH data available.


Related in: MedlinePlus