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An ontology driven clinical evidence service providing diagnostic decision support in family practice.

Corrigan D - AMIA Jt Summits Transl Sci Proc (2015)

Bottom Line: Formulation of a working diagnostic hypothesis in family practice requires consideration of many differential diagnoses associated with any presenting patient complaint.The solution implements ontology models of evidence accessible to consumers as a web service using open source components and standards.An implementation example is described that consumes the service to drive a diagnostic decision support tool developed for the TRANSFoRm project.

View Article: PubMed Central - PubMed

Affiliation: HRB Centre for Primary Care Research, Royal College of Surgeons in Ireland, Dublin, Ireland.

ABSTRACT
Formulation of a working diagnostic hypothesis in family practice requires consideration of many differential diagnoses associated with any presenting patient complaint. There follows a process of refinement of the differentials to consider, through ruling in or out each candidate differential based on the confirmed presence or absence of diagnostic cues elicited during patient consultation. The patient safety implications of diagnostic error are potentially severe for patient and clinician. This paper describes a clinical evidence service supporting this diagnostic process. It allows decision support consumers to provide coded evidence-based recommendations to assist with diagnostic hypothesis formulation, integrated with an EHR in primary care. The solution implements ontology models of evidence accessible to consumers as a web service using open source components and standards. An implementation example is described that consumes the service to drive a diagnostic decision support tool developed for the TRANSFoRm project.

No MeSH data available.


Related in: MedlinePlus

Example of cue ontology concept instance for ‘history of irritable bowel syndrome’.
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f2-2081312: Example of cue ontology concept instance for ‘history of irritable bowel syndrome’.

Mentions: Specifically we have supported interoperability with a single EHR vendor in the UK using NHS read codes version 3 (8). Localisation support to allow easier searching by a third party consumer for ontology terms using locally defined synonyms is provided for by the ‘synonym’ concept. An example of concepts and associated instances (in red) of the diagnostic cue concept for a patient history of irritable bowel syndrome, with an associated NHS read ‘14CF.00’ and local synonym ‘HO IBS’ is shown in figure 2. The ontology can support other coding schemes including ICP2, ICD10, SNOMED and UMLS (9–11).


An ontology driven clinical evidence service providing diagnostic decision support in family practice.

Corrigan D - AMIA Jt Summits Transl Sci Proc (2015)

Example of cue ontology concept instance for ‘history of irritable bowel syndrome’.
© Copyright Policy
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4525252&req=5

f2-2081312: Example of cue ontology concept instance for ‘history of irritable bowel syndrome’.
Mentions: Specifically we have supported interoperability with a single EHR vendor in the UK using NHS read codes version 3 (8). Localisation support to allow easier searching by a third party consumer for ontology terms using locally defined synonyms is provided for by the ‘synonym’ concept. An example of concepts and associated instances (in red) of the diagnostic cue concept for a patient history of irritable bowel syndrome, with an associated NHS read ‘14CF.00’ and local synonym ‘HO IBS’ is shown in figure 2. The ontology can support other coding schemes including ICP2, ICD10, SNOMED and UMLS (9–11).

Bottom Line: Formulation of a working diagnostic hypothesis in family practice requires consideration of many differential diagnoses associated with any presenting patient complaint.The solution implements ontology models of evidence accessible to consumers as a web service using open source components and standards.An implementation example is described that consumes the service to drive a diagnostic decision support tool developed for the TRANSFoRm project.

View Article: PubMed Central - PubMed

Affiliation: HRB Centre for Primary Care Research, Royal College of Surgeons in Ireland, Dublin, Ireland.

ABSTRACT
Formulation of a working diagnostic hypothesis in family practice requires consideration of many differential diagnoses associated with any presenting patient complaint. There follows a process of refinement of the differentials to consider, through ruling in or out each candidate differential based on the confirmed presence or absence of diagnostic cues elicited during patient consultation. The patient safety implications of diagnostic error are potentially severe for patient and clinician. This paper describes a clinical evidence service supporting this diagnostic process. It allows decision support consumers to provide coded evidence-based recommendations to assist with diagnostic hypothesis formulation, integrated with an EHR in primary care. The solution implements ontology models of evidence accessible to consumers as a web service using open source components and standards. An implementation example is described that consumes the service to drive a diagnostic decision support tool developed for the TRANSFoRm project.

No MeSH data available.


Related in: MedlinePlus