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Case report of renal cell carcinoma in automobile manufacturing factory worker due to trichloroethylene exposure in Korea.

Lee JH, Kim I, Seok H, Park I, Hwang J, Park JO, Won JU, Roh J - Ann Occup Environ Med (2015)

Bottom Line: The aim of this paper was report first case of renal cell carcinoma developed in a worker who worked in an automobile manufacture line which handles trichloroethylene in Korea.Evaluation Committee of Epidemiologic Survey decided that there are relevant relationship between the exposure and the disease, though we do not have exact data during that period, most experts agree that in every factories they used trichloroethylene without any direction.From the relevant medical history and the results of the usage of trichloroethylene in the relevant industries, and initial discovery of renal cell carcinoma at health inspection sonogram in 2001, it can be concluded that suggests significant causal relationship between the exposure to trichloroethylene and renal cell carcinoma onset, thus reporting it to be the first domestic case declared to be occupational disease.

View Article: PubMed Central - PubMed

Affiliation: Graduate School of Public Health, Yonsei University, 50 Seongsanno (134 Sinchon-dong), Seodaemun-gu, Seoul, South Korea ; The Institute for Occupational Health, Yonsei University College of Medicine, Seoul, South Korea.

ABSTRACT

Background: The aim of this paper was report first case of renal cell carcinoma developed in a worker who worked in an automobile manufacture line which handles trichloroethylene in Korea.

Case presentation: To clarify the relationship between the onset of renal cell carcinoma in 52-years old male worker and the exposure to trichloroethylene, document studies and work environment measurement were done. Past work environment exposure data were reviewed and medical history and surgery records of the worker were also reviewed. The patient had no personal risk factor related to renal cell carcinoma except for his smoking habit of quarter a pack per day for twenty years, and since trichloroethylene was not part of measurement criteria, past work environment risk assessment data could not verify the exposure. The exposure level is deduced by analyzing material exposure level of work environments which has similar processes in data from revised research of chemical exposure standard and work environment validity assessment. Evaluation Committee of Epidemiologic Survey decided that there are relevant relationship between the exposure and the disease, though we do not have exact data during that period, most experts agree that in every factories they used trichloroethylene without any direction.

Conclusions: From the relevant medical history and the results of the usage of trichloroethylene in the relevant industries, and initial discovery of renal cell carcinoma at health inspection sonogram in 2001, it can be concluded that suggests significant causal relationship between the exposure to trichloroethylene and renal cell carcinoma onset, thus reporting it to be the first domestic case declared to be occupational disease.

No MeSH data available.


Related in: MedlinePlus

CT scan of renal cell carcinoma (Arrow)
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Fig1: CT scan of renal cell carcinoma (Arrow)

Mentions: The patient has discovered a cystoma on the left kidney during regular medical check-up in 2003. The size of the cystoma has grown from the original 1.7 cm to 2.7 cm in 2011, therefore, nephrectomy on the left kidney was implemented after CT scan (Fig. 1). Afterwards, through biopsy, the definite diagnosis was renal cell carcinoma. After nephrectomy in 2011, having considered his occupational history to have connection with the renal cell carcinoma, the patient claimed to approve his cancer as occupational disease according to Industrial Accident Compensation Insurance Act.Fig. 1


Case report of renal cell carcinoma in automobile manufacturing factory worker due to trichloroethylene exposure in Korea.

Lee JH, Kim I, Seok H, Park I, Hwang J, Park JO, Won JU, Roh J - Ann Occup Environ Med (2015)

CT scan of renal cell carcinoma (Arrow)
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4522957&req=5

Fig1: CT scan of renal cell carcinoma (Arrow)
Mentions: The patient has discovered a cystoma on the left kidney during regular medical check-up in 2003. The size of the cystoma has grown from the original 1.7 cm to 2.7 cm in 2011, therefore, nephrectomy on the left kidney was implemented after CT scan (Fig. 1). Afterwards, through biopsy, the definite diagnosis was renal cell carcinoma. After nephrectomy in 2011, having considered his occupational history to have connection with the renal cell carcinoma, the patient claimed to approve his cancer as occupational disease according to Industrial Accident Compensation Insurance Act.Fig. 1

Bottom Line: The aim of this paper was report first case of renal cell carcinoma developed in a worker who worked in an automobile manufacture line which handles trichloroethylene in Korea.Evaluation Committee of Epidemiologic Survey decided that there are relevant relationship between the exposure and the disease, though we do not have exact data during that period, most experts agree that in every factories they used trichloroethylene without any direction.From the relevant medical history and the results of the usage of trichloroethylene in the relevant industries, and initial discovery of renal cell carcinoma at health inspection sonogram in 2001, it can be concluded that suggests significant causal relationship between the exposure to trichloroethylene and renal cell carcinoma onset, thus reporting it to be the first domestic case declared to be occupational disease.

View Article: PubMed Central - PubMed

Affiliation: Graduate School of Public Health, Yonsei University, 50 Seongsanno (134 Sinchon-dong), Seodaemun-gu, Seoul, South Korea ; The Institute for Occupational Health, Yonsei University College of Medicine, Seoul, South Korea.

ABSTRACT

Background: The aim of this paper was report first case of renal cell carcinoma developed in a worker who worked in an automobile manufacture line which handles trichloroethylene in Korea.

Case presentation: To clarify the relationship between the onset of renal cell carcinoma in 52-years old male worker and the exposure to trichloroethylene, document studies and work environment measurement were done. Past work environment exposure data were reviewed and medical history and surgery records of the worker were also reviewed. The patient had no personal risk factor related to renal cell carcinoma except for his smoking habit of quarter a pack per day for twenty years, and since trichloroethylene was not part of measurement criteria, past work environment risk assessment data could not verify the exposure. The exposure level is deduced by analyzing material exposure level of work environments which has similar processes in data from revised research of chemical exposure standard and work environment validity assessment. Evaluation Committee of Epidemiologic Survey decided that there are relevant relationship between the exposure and the disease, though we do not have exact data during that period, most experts agree that in every factories they used trichloroethylene without any direction.

Conclusions: From the relevant medical history and the results of the usage of trichloroethylene in the relevant industries, and initial discovery of renal cell carcinoma at health inspection sonogram in 2001, it can be concluded that suggests significant causal relationship between the exposure to trichloroethylene and renal cell carcinoma onset, thus reporting it to be the first domestic case declared to be occupational disease.

No MeSH data available.


Related in: MedlinePlus