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Posterior fossa ependymoblastoma diagnosed in the second month of life: uneventful 12 years survival after gross total resection followed by chemotherapy.

Due-Tønnessen BJ, Egge A, Lundar T, Krossnes B, Stensvold E, Due-Tønnessen P, Brandal P - Springerplus (2015)

Bottom Line: We report on an infant who underwent gross total resection (GTR) of a posterior fossa ependymoblastoma in the second month of life followed by chemotherapy with uneventful long-term survival for 12 years.Postoperative radiotherapy has been considered obligate to have a chance for prolonged survival, but is inadvisable in infants.To our knowledge, this is the first reported long-term survival in an infant treated for ependymoblastoma.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurosurgery, Oslo University Hospital, Postboks 4950, Nydalen, 0424 Oslo, Norway.

ABSTRACT
We report on an infant who underwent gross total resection (GTR) of a posterior fossa ependymoblastoma in the second month of life followed by chemotherapy with uneventful long-term survival for 12 years. Postoperative radiotherapy has been considered obligate to have a chance for prolonged survival, but is inadvisable in infants. To our knowledge, this is the first reported long-term survival in an infant treated for ependymoblastoma.

No MeSH data available.


Related in: MedlinePlus

Immediate postoperative MRI scans; a sagittal, b axial, white line demonstrating gross total resection.
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Fig2: Immediate postoperative MRI scans; a sagittal, b axial, white line demonstrating gross total resection.

Mentions: Operation Intraoperative external drainage of the cerebrospinal fluid (CSF) was established to control the intracranial pressure (ICP). A suboccipital craniotomy was performed in the mid-line. The tumor was microsurgically excised via the fourth ventricle to gross-total resection (GTR) of the tumor. The external drainage was terminated as CSF flow through the Sylvian aqueduct had been observed. Postoperative MRI scans performed in the same anesthetical procedure as the surgery confirmed the GTR (Fig. 2).Fig. 2


Posterior fossa ependymoblastoma diagnosed in the second month of life: uneventful 12 years survival after gross total resection followed by chemotherapy.

Due-Tønnessen BJ, Egge A, Lundar T, Krossnes B, Stensvold E, Due-Tønnessen P, Brandal P - Springerplus (2015)

Immediate postoperative MRI scans; a sagittal, b axial, white line demonstrating gross total resection.
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4522267&req=5

Fig2: Immediate postoperative MRI scans; a sagittal, b axial, white line demonstrating gross total resection.
Mentions: Operation Intraoperative external drainage of the cerebrospinal fluid (CSF) was established to control the intracranial pressure (ICP). A suboccipital craniotomy was performed in the mid-line. The tumor was microsurgically excised via the fourth ventricle to gross-total resection (GTR) of the tumor. The external drainage was terminated as CSF flow through the Sylvian aqueduct had been observed. Postoperative MRI scans performed in the same anesthetical procedure as the surgery confirmed the GTR (Fig. 2).Fig. 2

Bottom Line: We report on an infant who underwent gross total resection (GTR) of a posterior fossa ependymoblastoma in the second month of life followed by chemotherapy with uneventful long-term survival for 12 years.Postoperative radiotherapy has been considered obligate to have a chance for prolonged survival, but is inadvisable in infants.To our knowledge, this is the first reported long-term survival in an infant treated for ependymoblastoma.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurosurgery, Oslo University Hospital, Postboks 4950, Nydalen, 0424 Oslo, Norway.

ABSTRACT
We report on an infant who underwent gross total resection (GTR) of a posterior fossa ependymoblastoma in the second month of life followed by chemotherapy with uneventful long-term survival for 12 years. Postoperative radiotherapy has been considered obligate to have a chance for prolonged survival, but is inadvisable in infants. To our knowledge, this is the first reported long-term survival in an infant treated for ependymoblastoma.

No MeSH data available.


Related in: MedlinePlus