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Current status of Schistosoma mansoni and the factors associated with infection two years following mass drug administration programme among primary school children in Mwea irrigation scheme: A cross-sectional study.

Masaku J, Madigu N, Okoyo C, Njenga SM - BMC Public Health (2015)

Bottom Line: The overall prevalence of S. mansoni was 53.7 %, (95%CI: 49.0-59.0, p-value = 0.000).Male children had higher prevalence of infection, 66.1 % (95%CI: 59.8-73.2, p-value = 0.000) compared to females.We suggest that treatment should be continued in the school children at regular intervals, monitoring and surveillance intensified to ensure interruption of transmission areas.

View Article: PubMed Central - PubMed

Affiliation: Esatern and Southern Africa Centre of International Parasite Control (ESACIPAC), Kenya Medical Research Institute (KEMRI), P.O Box 54840 - 00200, Nairobi, Kenya. jmasaku@kemri.org.

ABSTRACT

Background: Schistosomiasis is a major public health problem in Kenya as well as in many other tropical countries and is considered one of the most prevalent diseases in the rural population. Between 2004 and 2009, primary school children in Mwea irrigation scheme were treated for Schistosoma mansoni. In the four year control programme, there was occurrence of light re-infection with S. mansoni. Therefore, the aim of this study was to assess the current prevalence of S. mansoni, infection two years after the withdrawal of mass drug administration (MDA) programme.

Methods: We carried out a cross-sectional study on a population of 387 children attending 3 primary schools located in Mwea irrigation scheme. Children, aged 8-16 years were interviewed and screened for S. mansoni using duplicate Kato-Katz thick smears. Comparisons of prevalence by age group and gender were tested for significance on the basis of the Wald test. Best prediction factors for infection with S. mansoni were selected using forward - stepwise variable selection method.

Results: The overall prevalence of S. mansoni was 53.7 %, (95%CI: 49.0-59.0, p-value = 0.000). Male children had higher prevalence of infection, 66.1 % (95%CI: 59.8-73.2, p-value = 0.000) compared to females. The gender (sex) of a child was the only factor reported to be significantly associated with S. mansoni infection, (OR = 1.9, p-value = 0.015, 95%CI: 1.13-3.21).

Conclusions: There was high prevalence of S. mansoni infections in the study area, two years after the withdrawal of MDA programme. We suggest that treatment should be continued in the school children at regular intervals, monitoring and surveillance intensified to ensure interruption of transmission areas.

No MeSH data available.


Related in: MedlinePlus

The geographical locations of the study schools
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Fig1: The geographical locations of the study schools

Mentions: The study was conducted in Mwea irrigation scheme located in Kirinyaga County, central Kenya. Administratively, the new upgraded Kirinyaga County has two districts (Mwea East and Mwea West). The county is located about 100 km north east of Nairobi, Kenya. It covers an area of 513 km2 and it is estimated to have 51,444 households and a total population of 176,261 persons [31]. There are 58,970 school age children (5–19) in Mwea [31]. The mean annual rainfall in this area is in the range of 1200–1600 mm per year and varies by the time of year (Fig. 1). Mwea West district, were the study was conducted has two locations (Kangai and Thiba) and seven villages. The main socio-economic activity in this area is rice farming, which is done by gravity flow irrigation using water from river Thiba and Nyamindi. Mwea west district is endemic for both S. mansoni and Soil transmitted helminths (STH). The geographical locations of thesurveyed schools and the two locations are shown in Fig. 1 below.Fig 1


Current status of Schistosoma mansoni and the factors associated with infection two years following mass drug administration programme among primary school children in Mwea irrigation scheme: A cross-sectional study.

Masaku J, Madigu N, Okoyo C, Njenga SM - BMC Public Health (2015)

The geographical locations of the study schools
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4522152&req=5

Fig1: The geographical locations of the study schools
Mentions: The study was conducted in Mwea irrigation scheme located in Kirinyaga County, central Kenya. Administratively, the new upgraded Kirinyaga County has two districts (Mwea East and Mwea West). The county is located about 100 km north east of Nairobi, Kenya. It covers an area of 513 km2 and it is estimated to have 51,444 households and a total population of 176,261 persons [31]. There are 58,970 school age children (5–19) in Mwea [31]. The mean annual rainfall in this area is in the range of 1200–1600 mm per year and varies by the time of year (Fig. 1). Mwea West district, were the study was conducted has two locations (Kangai and Thiba) and seven villages. The main socio-economic activity in this area is rice farming, which is done by gravity flow irrigation using water from river Thiba and Nyamindi. Mwea west district is endemic for both S. mansoni and Soil transmitted helminths (STH). The geographical locations of thesurveyed schools and the two locations are shown in Fig. 1 below.Fig 1

Bottom Line: The overall prevalence of S. mansoni was 53.7 %, (95%CI: 49.0-59.0, p-value = 0.000).Male children had higher prevalence of infection, 66.1 % (95%CI: 59.8-73.2, p-value = 0.000) compared to females.We suggest that treatment should be continued in the school children at regular intervals, monitoring and surveillance intensified to ensure interruption of transmission areas.

View Article: PubMed Central - PubMed

Affiliation: Esatern and Southern Africa Centre of International Parasite Control (ESACIPAC), Kenya Medical Research Institute (KEMRI), P.O Box 54840 - 00200, Nairobi, Kenya. jmasaku@kemri.org.

ABSTRACT

Background: Schistosomiasis is a major public health problem in Kenya as well as in many other tropical countries and is considered one of the most prevalent diseases in the rural population. Between 2004 and 2009, primary school children in Mwea irrigation scheme were treated for Schistosoma mansoni. In the four year control programme, there was occurrence of light re-infection with S. mansoni. Therefore, the aim of this study was to assess the current prevalence of S. mansoni, infection two years after the withdrawal of mass drug administration (MDA) programme.

Methods: We carried out a cross-sectional study on a population of 387 children attending 3 primary schools located in Mwea irrigation scheme. Children, aged 8-16 years were interviewed and screened for S. mansoni using duplicate Kato-Katz thick smears. Comparisons of prevalence by age group and gender were tested for significance on the basis of the Wald test. Best prediction factors for infection with S. mansoni were selected using forward - stepwise variable selection method.

Results: The overall prevalence of S. mansoni was 53.7 %, (95%CI: 49.0-59.0, p-value = 0.000). Male children had higher prevalence of infection, 66.1 % (95%CI: 59.8-73.2, p-value = 0.000) compared to females. The gender (sex) of a child was the only factor reported to be significantly associated with S. mansoni infection, (OR = 1.9, p-value = 0.015, 95%CI: 1.13-3.21).

Conclusions: There was high prevalence of S. mansoni infections in the study area, two years after the withdrawal of MDA programme. We suggest that treatment should be continued in the school children at regular intervals, monitoring and surveillance intensified to ensure interruption of transmission areas.

No MeSH data available.


Related in: MedlinePlus