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Achievement of Target Blood Pressure Levels among Japanese Workers with Hypertension and Healthy Lifestyle Characteristics Associated with Therapeutic Failure.

Kudo N, Yokokawa H, Fukuda H, Sanada H, Miwa Y, Hisaoka T, Isonuma H - PLoS ONE (2015)

Bottom Line: Multivariate analysis identified healthy lifestyle characteristics associated with "therapeutic failure" of target blood pressure.A body mass index of 18.5-24.9 and non-daily alcohol consumption were protective factors, and adequate sleep was found to contribute to therapeutic success.We found low achievement rates for treatment goals among patients with chronic kidney disease and diabetes mellitus.

View Article: PubMed Central - PubMed

Affiliation: Department of General Medicine, Juntendo University School of Medicine, Tokyo, Japan; Tokorozawa Medical Clinic, Tokorozawa City, Saitama, Japan.

ABSTRACT

Background: Few studies have examined Japanese with regard to the achievement rates for target blood pressure levels, or the relationship between these rates and healthy lifestyle characteristics in patients with hypertension as defined by the newly established hypertension management guidelines (JSH2014). The aim of this study was to elucidate achievement rates and examine healthy lifestyle characteristics associated with achievement status among Japanese.

Methods: This cross-sectional study, conducted in January-December 2012, examined blood pressure control and healthy lifestyle characteristics in 8,001 Japanese workers with hypertension (mean age, 57.0 years; 78.8% were men) who participated in a workplace health checkup. Data were collected from workplace medical checkup records and participants' self-administered questionnaires. We divided into 5 groups [G1; young, middle-aged, and early-phase elderly patients (65-74 years old) without diabetes mellitus or chronic kidney disease (CKD) (<140/90 mmHg), G2; late-phase elderly patients (≥75 years old) without diabetes mellitus or CKD (<150/90 mmHg), G3; diabetic patients (<130/80 mmHg), G4; patients with CKD (<130/80 mmHg), and G5; patients with cerebrovascular and/or coronary artery diseases (<140/90 mmHg)] according to JSH2014. And then, achievement rates were calculated in each group. Multivariate analysis identified healthy lifestyle characteristics associated with "therapeutic failure" of target blood pressure.

Results: Target blood pressures were achieved by 60.2% of young, middle-aged, and early-phase elderly patients (G1), 71.4% of late-phase elderly patients (G2), 30.5% of diabetic patients (G3), 33.4% of those with chronic kidney disease (G4), and 66.0% of those with cerebrovascular and/or coronary artery diseases (G5). A body mass index of 18.5-24.9 and non-daily alcohol consumption were protective factors, and adequate sleep was found to contribute to therapeutic success.

Discussion: We found low achievement rates for treatment goals among patients with chronic kidney disease and diabetes mellitus. Maintaining an ideal body weight and adequate alcohol consumption may help with blood pressure control. Lifestyle modification may be necessary for better management of hypertension.

No MeSH data available.


Related in: MedlinePlus

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pone.0133641.g001: Patients’ registration and flow.

Mentions: The present cross-sectional study screened 136,770 Japanese individuals who participated in a workplace health checkup conducted by the Tokyo Health Service Association from January to December in 2012 in Tokyo, Japan. Of these, 9,790 who were receiving treatment for hypertension, and 1,789 were excluded due to data missing. Thus 8,001 were included in the present study (Fig 1).


Achievement of Target Blood Pressure Levels among Japanese Workers with Hypertension and Healthy Lifestyle Characteristics Associated with Therapeutic Failure.

Kudo N, Yokokawa H, Fukuda H, Sanada H, Miwa Y, Hisaoka T, Isonuma H - PLoS ONE (2015)

Patients’ registration and flow.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4520602&req=5

pone.0133641.g001: Patients’ registration and flow.
Mentions: The present cross-sectional study screened 136,770 Japanese individuals who participated in a workplace health checkup conducted by the Tokyo Health Service Association from January to December in 2012 in Tokyo, Japan. Of these, 9,790 who were receiving treatment for hypertension, and 1,789 were excluded due to data missing. Thus 8,001 were included in the present study (Fig 1).

Bottom Line: Multivariate analysis identified healthy lifestyle characteristics associated with "therapeutic failure" of target blood pressure.A body mass index of 18.5-24.9 and non-daily alcohol consumption were protective factors, and adequate sleep was found to contribute to therapeutic success.We found low achievement rates for treatment goals among patients with chronic kidney disease and diabetes mellitus.

View Article: PubMed Central - PubMed

Affiliation: Department of General Medicine, Juntendo University School of Medicine, Tokyo, Japan; Tokorozawa Medical Clinic, Tokorozawa City, Saitama, Japan.

ABSTRACT

Background: Few studies have examined Japanese with regard to the achievement rates for target blood pressure levels, or the relationship between these rates and healthy lifestyle characteristics in patients with hypertension as defined by the newly established hypertension management guidelines (JSH2014). The aim of this study was to elucidate achievement rates and examine healthy lifestyle characteristics associated with achievement status among Japanese.

Methods: This cross-sectional study, conducted in January-December 2012, examined blood pressure control and healthy lifestyle characteristics in 8,001 Japanese workers with hypertension (mean age, 57.0 years; 78.8% were men) who participated in a workplace health checkup. Data were collected from workplace medical checkup records and participants' self-administered questionnaires. We divided into 5 groups [G1; young, middle-aged, and early-phase elderly patients (65-74 years old) without diabetes mellitus or chronic kidney disease (CKD) (<140/90 mmHg), G2; late-phase elderly patients (≥75 years old) without diabetes mellitus or CKD (<150/90 mmHg), G3; diabetic patients (<130/80 mmHg), G4; patients with CKD (<130/80 mmHg), and G5; patients with cerebrovascular and/or coronary artery diseases (<140/90 mmHg)] according to JSH2014. And then, achievement rates were calculated in each group. Multivariate analysis identified healthy lifestyle characteristics associated with "therapeutic failure" of target blood pressure.

Results: Target blood pressures were achieved by 60.2% of young, middle-aged, and early-phase elderly patients (G1), 71.4% of late-phase elderly patients (G2), 30.5% of diabetic patients (G3), 33.4% of those with chronic kidney disease (G4), and 66.0% of those with cerebrovascular and/or coronary artery diseases (G5). A body mass index of 18.5-24.9 and non-daily alcohol consumption were protective factors, and adequate sleep was found to contribute to therapeutic success.

Discussion: We found low achievement rates for treatment goals among patients with chronic kidney disease and diabetes mellitus. Maintaining an ideal body weight and adequate alcohol consumption may help with blood pressure control. Lifestyle modification may be necessary for better management of hypertension.

No MeSH data available.


Related in: MedlinePlus