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Malignant melanoma of the lung: case series.

Postrzech-Adamczyk K, Chabowski M, Głuszczyk-Ferenc B, Wodzińska A, Muszczyńska-Bernhard B, Szuba A, Janczak D - Kardiochir Torakochirurgia Pol (2015)

Bottom Line: For the diagnosis of primary lung melanoma, strict histopathological and clinical criteria should be met.The first 2 case studies present primary lung melanomas, while the last one shows late lung metastasis of tumor originated from vaginal mucosa.Abstract available from the publisher.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, 4 Clinical Military Hospital, Wroclaw, Poland.

ABSTRACT
Extracutaneous locations of primary malignant melanoma are rare. In the respiratory system most melanomas present as metastatic tumors. For the diagnosis of primary lung melanoma, strict histopathological and clinical criteria should be met. In this paper we present three cases of malignant melanoma which showed in the respiratory system. The first 2 case studies present primary lung melanomas, while the last one shows late lung metastasis of tumor originated from vaginal mucosa. The treatment of choice for localized disease as well as single metastasis is surgical excision.

No MeSH data available.


Related in: MedlinePlus

Female, 50-year-old. Computed tomography examination of the chest. Rounded nodules in both lungs
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Figure 0005: Female, 50-year-old. Computed tomography examination of the chest. Rounded nodules in both lungs

Mentions: A 50-year-old female after surgically treated MM of vaginal mucosa 7 years before and reoperation for local recurrence 4 years later presented with persistent cough. Computed tomography of the chest revealed 3 circular solid tumors (0.6 cm in diameter) in the right lung and 2 similar lesions in the left lung (Fig. 5). Positron emission tomography scan showed increased glucose metabolism in the same locations and additionally in the iliac lymph nodes. The patient was qualified for surgical excision of lung tumors. Right thoracotomy and subsequently left thoracotomy with wedge resection of metastatic tumors was performed. Histopathological examination confirmed metastatic malignant melanoma. The patient was referred to adjuvant chemotherapy. Despite treatment, control PET scan revealed rapid progression and the patient died 15 months later.


Malignant melanoma of the lung: case series.

Postrzech-Adamczyk K, Chabowski M, Głuszczyk-Ferenc B, Wodzińska A, Muszczyńska-Bernhard B, Szuba A, Janczak D - Kardiochir Torakochirurgia Pol (2015)

Female, 50-year-old. Computed tomography examination of the chest. Rounded nodules in both lungs
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4520507&req=5

Figure 0005: Female, 50-year-old. Computed tomography examination of the chest. Rounded nodules in both lungs
Mentions: A 50-year-old female after surgically treated MM of vaginal mucosa 7 years before and reoperation for local recurrence 4 years later presented with persistent cough. Computed tomography of the chest revealed 3 circular solid tumors (0.6 cm in diameter) in the right lung and 2 similar lesions in the left lung (Fig. 5). Positron emission tomography scan showed increased glucose metabolism in the same locations and additionally in the iliac lymph nodes. The patient was qualified for surgical excision of lung tumors. Right thoracotomy and subsequently left thoracotomy with wedge resection of metastatic tumors was performed. Histopathological examination confirmed metastatic malignant melanoma. The patient was referred to adjuvant chemotherapy. Despite treatment, control PET scan revealed rapid progression and the patient died 15 months later.

Bottom Line: For the diagnosis of primary lung melanoma, strict histopathological and clinical criteria should be met.The first 2 case studies present primary lung melanomas, while the last one shows late lung metastasis of tumor originated from vaginal mucosa.Abstract available from the publisher.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, 4 Clinical Military Hospital, Wroclaw, Poland.

ABSTRACT
Extracutaneous locations of primary malignant melanoma are rare. In the respiratory system most melanomas present as metastatic tumors. For the diagnosis of primary lung melanoma, strict histopathological and clinical criteria should be met. In this paper we present three cases of malignant melanoma which showed in the respiratory system. The first 2 case studies present primary lung melanomas, while the last one shows late lung metastasis of tumor originated from vaginal mucosa. The treatment of choice for localized disease as well as single metastasis is surgical excision.

No MeSH data available.


Related in: MedlinePlus