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Malignant melanoma of the lung: case series.

Postrzech-Adamczyk K, Chabowski M, Głuszczyk-Ferenc B, Wodzińska A, Muszczyńska-Bernhard B, Szuba A, Janczak D - Kardiochir Torakochirurgia Pol (2015)

Bottom Line: For the diagnosis of primary lung melanoma, strict histopathological and clinical criteria should be met.The first 2 case studies present primary lung melanomas, while the last one shows late lung metastasis of tumor originated from vaginal mucosa.Abstract available from the publisher.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, 4 Clinical Military Hospital, Wroclaw, Poland.

ABSTRACT
Extracutaneous locations of primary malignant melanoma are rare. In the respiratory system most melanomas present as metastatic tumors. For the diagnosis of primary lung melanoma, strict histopathological and clinical criteria should be met. In this paper we present three cases of malignant melanoma which showed in the respiratory system. The first 2 case studies present primary lung melanomas, while the last one shows late lung metastasis of tumor originated from vaginal mucosa. The treatment of choice for localized disease as well as single metastasis is surgical excision.

No MeSH data available.


Related in: MedlinePlus

Male, 63-year-old, right-sided hemiparesis. Axial scan of non-contrast computed tomography examination of the head. Lesion in the left parietal lobe with hyperdense fluid-fluid level, surrounded with white matter edema that could be suspicious for the brain metastasis with the hemorrhage
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Figure 0003: Male, 63-year-old, right-sided hemiparesis. Axial scan of non-contrast computed tomography examination of the head. Lesion in the left parietal lobe with hyperdense fluid-fluid level, surrounded with white matter edema that could be suspicious for the brain metastasis with the hemorrhage

Mentions: A 63-year-old male with a medical history of hypertension and diabetes mellitus presented in the Emergency Department with right-sided hemiparesis lasting for 2 days. Computed tomography of the head showed numerous supra- and infratentorial lesions with hemorrhage (Fig. 3), chest X-ray revealed a round shadow in the middle zone of the left lung. For further assessment the patient was admitted to the Department of Internal Medicine. Physical examination was unremarkable except for a right-sided hemiparesis, no skin lesions suggestive of skin cancer were found. Computed tomography of the chest showed solid tumor in the upper lobe of the left lung and one similar smaller lesion in the same lung (Fig. 4). Bronchoscopy did not yield diagnosis thus transthoracic biopsy was performed. Cytological examination disclosed malignant melanoma cells. Due to disseminated lesions in the central nervous system and the right lung the patient was disqualified from surgery. At that moment, because of hemorrhagic changes in the brain radiotherapy was not indicated either. Treatment with systemic corticosteroids was introduced and improvement of hemiparesis was observed although the general condition of the patient gradually deteriorated. Due to no available effective management further examinations were not performed. With the diagnosis of stage IV malignant melanoma in the stable clinical condition the patient was released to palliative care.


Malignant melanoma of the lung: case series.

Postrzech-Adamczyk K, Chabowski M, Głuszczyk-Ferenc B, Wodzińska A, Muszczyńska-Bernhard B, Szuba A, Janczak D - Kardiochir Torakochirurgia Pol (2015)

Male, 63-year-old, right-sided hemiparesis. Axial scan of non-contrast computed tomography examination of the head. Lesion in the left parietal lobe with hyperdense fluid-fluid level, surrounded with white matter edema that could be suspicious for the brain metastasis with the hemorrhage
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4520507&req=5

Figure 0003: Male, 63-year-old, right-sided hemiparesis. Axial scan of non-contrast computed tomography examination of the head. Lesion in the left parietal lobe with hyperdense fluid-fluid level, surrounded with white matter edema that could be suspicious for the brain metastasis with the hemorrhage
Mentions: A 63-year-old male with a medical history of hypertension and diabetes mellitus presented in the Emergency Department with right-sided hemiparesis lasting for 2 days. Computed tomography of the head showed numerous supra- and infratentorial lesions with hemorrhage (Fig. 3), chest X-ray revealed a round shadow in the middle zone of the left lung. For further assessment the patient was admitted to the Department of Internal Medicine. Physical examination was unremarkable except for a right-sided hemiparesis, no skin lesions suggestive of skin cancer were found. Computed tomography of the chest showed solid tumor in the upper lobe of the left lung and one similar smaller lesion in the same lung (Fig. 4). Bronchoscopy did not yield diagnosis thus transthoracic biopsy was performed. Cytological examination disclosed malignant melanoma cells. Due to disseminated lesions in the central nervous system and the right lung the patient was disqualified from surgery. At that moment, because of hemorrhagic changes in the brain radiotherapy was not indicated either. Treatment with systemic corticosteroids was introduced and improvement of hemiparesis was observed although the general condition of the patient gradually deteriorated. Due to no available effective management further examinations were not performed. With the diagnosis of stage IV malignant melanoma in the stable clinical condition the patient was released to palliative care.

Bottom Line: For the diagnosis of primary lung melanoma, strict histopathological and clinical criteria should be met.The first 2 case studies present primary lung melanomas, while the last one shows late lung metastasis of tumor originated from vaginal mucosa.Abstract available from the publisher.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, 4 Clinical Military Hospital, Wroclaw, Poland.

ABSTRACT
Extracutaneous locations of primary malignant melanoma are rare. In the respiratory system most melanomas present as metastatic tumors. For the diagnosis of primary lung melanoma, strict histopathological and clinical criteria should be met. In this paper we present three cases of malignant melanoma which showed in the respiratory system. The first 2 case studies present primary lung melanomas, while the last one shows late lung metastasis of tumor originated from vaginal mucosa. The treatment of choice for localized disease as well as single metastasis is surgical excision.

No MeSH data available.


Related in: MedlinePlus