Limits...
High-Resolution Imaging of the Optic Nerve and Retina in Optic Nerve Hypoplasia.

Pilat A, Sibley D, McLean RJ, Proudlock FA, Gottlob I - Ophthalmology (2015)

Bottom Line: Patients with ONH had significantly smaller discs (P < 0.03 and P < 0.001 compared with unaffected eye and healthy controls, respectively), horizontal cup diameter (P < 0.02 for both), and cup depth (P < 0.02 and P < 0.01, respectively).In the macula, significantly thinner RNFL (nasally), ganglion cell layer (GCL) (nasally and temporally), inner plexiform layer (IPL) (nasally), outer nuclear layer (ONL) (nasally), and inner segment (centrally and temporally) were found in patients with ONH compared with the control group (P < 0.05 for all comparisons).Visual acuity and presence of septo-optic dysplasia were associated with changes in GCL and IPL.

View Article: PubMed Central - PubMed

Affiliation: Ophthalmology Group, University of Leicester, Robert Kilpatrick Clinical Sciences Building, Leicester Royal Infirmary, Leicester, United Kingdom.

Show MeSH

Related in: MedlinePlus

Average thickness of the peripapillary retinal nerve fiber layer (RNFL) in patients with optic nerve hypoplasia (ONH) (affected and unaffected eyes) and healthy controls nasally and temporally from the disc center. Error bars are standard deviations.
© Copyright Policy - CC BY-NC-ND
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4518044&req=5

fig6: Average thickness of the peripapillary retinal nerve fiber layer (RNFL) in patients with optic nerve hypoplasia (ONH) (affected and unaffected eyes) and healthy controls nasally and temporally from the disc center. Error bars are standard deviations.

Mentions: Peripapillary RNFL was significantly thinner in the affected eye of patients with ONH compared with controls, with similar differences being observed in both nasal and temporal RNFL (54% and 68% of control values, respectively) (Fig 6). The RNFL thicknesses for the clinically unaffected eyes of patients with ONH were approximately midway between thicknesses in affected eyes of patients with ONH and controls. We found no significant difference in peripapillary RNFL between the 2 eyes in patients with bilaterally hypoplastic discs for any optic disc parameter.


High-Resolution Imaging of the Optic Nerve and Retina in Optic Nerve Hypoplasia.

Pilat A, Sibley D, McLean RJ, Proudlock FA, Gottlob I - Ophthalmology (2015)

Average thickness of the peripapillary retinal nerve fiber layer (RNFL) in patients with optic nerve hypoplasia (ONH) (affected and unaffected eyes) and healthy controls nasally and temporally from the disc center. Error bars are standard deviations.
© Copyright Policy - CC BY-NC-ND
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4518044&req=5

fig6: Average thickness of the peripapillary retinal nerve fiber layer (RNFL) in patients with optic nerve hypoplasia (ONH) (affected and unaffected eyes) and healthy controls nasally and temporally from the disc center. Error bars are standard deviations.
Mentions: Peripapillary RNFL was significantly thinner in the affected eye of patients with ONH compared with controls, with similar differences being observed in both nasal and temporal RNFL (54% and 68% of control values, respectively) (Fig 6). The RNFL thicknesses for the clinically unaffected eyes of patients with ONH were approximately midway between thicknesses in affected eyes of patients with ONH and controls. We found no significant difference in peripapillary RNFL between the 2 eyes in patients with bilaterally hypoplastic discs for any optic disc parameter.

Bottom Line: Patients with ONH had significantly smaller discs (P < 0.03 and P < 0.001 compared with unaffected eye and healthy controls, respectively), horizontal cup diameter (P < 0.02 for both), and cup depth (P < 0.02 and P < 0.01, respectively).In the macula, significantly thinner RNFL (nasally), ganglion cell layer (GCL) (nasally and temporally), inner plexiform layer (IPL) (nasally), outer nuclear layer (ONL) (nasally), and inner segment (centrally and temporally) were found in patients with ONH compared with the control group (P < 0.05 for all comparisons).Visual acuity and presence of septo-optic dysplasia were associated with changes in GCL and IPL.

View Article: PubMed Central - PubMed

Affiliation: Ophthalmology Group, University of Leicester, Robert Kilpatrick Clinical Sciences Building, Leicester Royal Infirmary, Leicester, United Kingdom.

Show MeSH
Related in: MedlinePlus