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Biological Activity of Recently Discovered Halogenated Marine Natural Products.

Gribble GW - Mar Drugs (2015)

Bottom Line: This review presents the biological activity-antibacterial, antifungal, anti-parasitic, antiviral, antitumor, antiinflammatory, antioxidant, and enzymatic activity-of halogenated marine natural products discovered in the past five years.Newly discovered examples that do not report biological activity are not included.

View Article: PubMed Central - PubMed

Affiliation: Department of Chemistry, Dartmouth College, Hanover, NH 03755, USA. gordon.w.gribble@dartmouth.edu.

ABSTRACT
This review presents the biological activity-antibacterial, antifungal, anti-parasitic, antiviral, antitumor, antiinflammatory, antioxidant, and enzymatic activity-of halogenated marine natural products discovered in the past five years. Newly discovered examples that do not report biological activity are not included.

No MeSH data available.


Structures of selected dichotellide briarane diterpenoids from Dichotella gemmacea [34].
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marinedrugs-13-04044-f002: Structures of selected dichotellide briarane diterpenoids from Dichotella gemmacea [34].

Mentions: The prolific gorgonian Dichotella gemmacea is also the source of numerous new briarane diterpenoids, the dichotellides, many of which contain chlorine or iodine or both [32,33,34]. In particular, of the 16 novel briarane diterpenoids, dichotellides F–U, found in Dichotella gemmacea, H (13), I (14), K (15), L (16), M (17), N (18), O (19), P (20), and U (21) exhibit potent antifouling activities (Figure 2; Table 1) [34].


Biological Activity of Recently Discovered Halogenated Marine Natural Products.

Gribble GW - Mar Drugs (2015)

Structures of selected dichotellide briarane diterpenoids from Dichotella gemmacea [34].
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4515607&req=5

marinedrugs-13-04044-f002: Structures of selected dichotellide briarane diterpenoids from Dichotella gemmacea [34].
Mentions: The prolific gorgonian Dichotella gemmacea is also the source of numerous new briarane diterpenoids, the dichotellides, many of which contain chlorine or iodine or both [32,33,34]. In particular, of the 16 novel briarane diterpenoids, dichotellides F–U, found in Dichotella gemmacea, H (13), I (14), K (15), L (16), M (17), N (18), O (19), P (20), and U (21) exhibit potent antifouling activities (Figure 2; Table 1) [34].

Bottom Line: This review presents the biological activity-antibacterial, antifungal, anti-parasitic, antiviral, antitumor, antiinflammatory, antioxidant, and enzymatic activity-of halogenated marine natural products discovered in the past five years.Newly discovered examples that do not report biological activity are not included.

View Article: PubMed Central - PubMed

Affiliation: Department of Chemistry, Dartmouth College, Hanover, NH 03755, USA. gordon.w.gribble@dartmouth.edu.

ABSTRACT
This review presents the biological activity-antibacterial, antifungal, anti-parasitic, antiviral, antitumor, antiinflammatory, antioxidant, and enzymatic activity-of halogenated marine natural products discovered in the past five years. Newly discovered examples that do not report biological activity are not included.

No MeSH data available.