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A Case of Primary Breast Diffuse Large B-Cell Lymphoma Treated with Chemotherapy Followed by Elective Field Radiation Therapy: A Brief Treatment Pattern Review from a Radiation Oncologist's Point of View.

Lee KC, Lee SH, Sung K, Ahn SH, Choi J, Lee SH, Lee JH, Hong J, Park SH - Case Rep Oncol Med (2015)

Bottom Line: Radiation therapy including the right whole breast and ipsilateral axilla and supraclavicular lymph node was performed after the patient received four courses of R-CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisolone plus rituximab) chemotherapy.At the follow-up period of 42 months, the patient is surviving with no evidence of disease.No morbidities occurred in this patient during the follow-up period.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiation Oncology, Gil Medical Center, School of Medicine, Gachon University, Incheon 405-760, Republic of Korea.

ABSTRACT
We here report a case of primary breast lymphoma (PBL). A 44-year-old woman presented with a painless mass in the right breast. Fine needle aspiration cytology and excisional biopsy were performed. Excisional biopsy revealed low grade lymphoma, which was subsequently confirmed with histopathology and diagnosed as diffuse large B-cell lymphoma (DLBCL). A chest computed tomography scan revealed a 3.5 cm sized breast mass with skin thickening and a small sized lymphadenopathy in the ipsilateral axilla. Radiation therapy including the right whole breast and ipsilateral axilla and supraclavicular lymph node was performed after the patient received four courses of R-CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisolone plus rituximab) chemotherapy. At the follow-up period of 42 months, the patient is surviving with no evidence of disease. No morbidities occurred in this patient during the follow-up period. We also briefly review the current practice pattern in PBL patients with DLBCL.

No MeSH data available.


Related in: MedlinePlus

F-18 fluorodeoxyglucose positron emission tomography/computed tomography (CT) reveals a hypermetabolic lesion (arrows) in the right breast (a) with mild hypermetabolic uptake in the ipsilateral axilla (b) and about a 3.5 cm sized right breast mass (c) with skin thickening. A small (7 mm) sized lymphadenopathy is observed in the ipsilateral axilla (d) on a plain contrast CT scan of the chest.
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fig2: F-18 fluorodeoxyglucose positron emission tomography/computed tomography (CT) reveals a hypermetabolic lesion (arrows) in the right breast (a) with mild hypermetabolic uptake in the ipsilateral axilla (b) and about a 3.5 cm sized right breast mass (c) with skin thickening. A small (7 mm) sized lymphadenopathy is observed in the ipsilateral axilla (d) on a plain contrast CT scan of the chest.

Mentions: Chest and abdominal computed tomography (CT) and positive emission tomography (PET) scans were evaluated for the staging workup. A bone-marrow (BM) biopsy was also performed. The chest CT revealed a 3.5 cm sized breast mass with skin thickening and a small (7 mm) sized lymphadenopathy in the ipsilateral axilla. A PET scan showed hypermetabolic uptake in the UOQ of the right breast with mild hypermetabolic uptake in the ipsilateral axilla (Figure 2). The patient was diagnosed with DLBCL. The BM biopsy showed a negative result for lymphomatous infiltration. The patient was diagnosed with stage IEA primary breast lymphoma according to the Ann Arbor staging system.


A Case of Primary Breast Diffuse Large B-Cell Lymphoma Treated with Chemotherapy Followed by Elective Field Radiation Therapy: A Brief Treatment Pattern Review from a Radiation Oncologist's Point of View.

Lee KC, Lee SH, Sung K, Ahn SH, Choi J, Lee SH, Lee JH, Hong J, Park SH - Case Rep Oncol Med (2015)

F-18 fluorodeoxyglucose positron emission tomography/computed tomography (CT) reveals a hypermetabolic lesion (arrows) in the right breast (a) with mild hypermetabolic uptake in the ipsilateral axilla (b) and about a 3.5 cm sized right breast mass (c) with skin thickening. A small (7 mm) sized lymphadenopathy is observed in the ipsilateral axilla (d) on a plain contrast CT scan of the chest.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4515502&req=5

fig2: F-18 fluorodeoxyglucose positron emission tomography/computed tomography (CT) reveals a hypermetabolic lesion (arrows) in the right breast (a) with mild hypermetabolic uptake in the ipsilateral axilla (b) and about a 3.5 cm sized right breast mass (c) with skin thickening. A small (7 mm) sized lymphadenopathy is observed in the ipsilateral axilla (d) on a plain contrast CT scan of the chest.
Mentions: Chest and abdominal computed tomography (CT) and positive emission tomography (PET) scans were evaluated for the staging workup. A bone-marrow (BM) biopsy was also performed. The chest CT revealed a 3.5 cm sized breast mass with skin thickening and a small (7 mm) sized lymphadenopathy in the ipsilateral axilla. A PET scan showed hypermetabolic uptake in the UOQ of the right breast with mild hypermetabolic uptake in the ipsilateral axilla (Figure 2). The patient was diagnosed with DLBCL. The BM biopsy showed a negative result for lymphomatous infiltration. The patient was diagnosed with stage IEA primary breast lymphoma according to the Ann Arbor staging system.

Bottom Line: Radiation therapy including the right whole breast and ipsilateral axilla and supraclavicular lymph node was performed after the patient received four courses of R-CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisolone plus rituximab) chemotherapy.At the follow-up period of 42 months, the patient is surviving with no evidence of disease.No morbidities occurred in this patient during the follow-up period.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiation Oncology, Gil Medical Center, School of Medicine, Gachon University, Incheon 405-760, Republic of Korea.

ABSTRACT
We here report a case of primary breast lymphoma (PBL). A 44-year-old woman presented with a painless mass in the right breast. Fine needle aspiration cytology and excisional biopsy were performed. Excisional biopsy revealed low grade lymphoma, which was subsequently confirmed with histopathology and diagnosed as diffuse large B-cell lymphoma (DLBCL). A chest computed tomography scan revealed a 3.5 cm sized breast mass with skin thickening and a small sized lymphadenopathy in the ipsilateral axilla. Radiation therapy including the right whole breast and ipsilateral axilla and supraclavicular lymph node was performed after the patient received four courses of R-CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisolone plus rituximab) chemotherapy. At the follow-up period of 42 months, the patient is surviving with no evidence of disease. No morbidities occurred in this patient during the follow-up period. We also briefly review the current practice pattern in PBL patients with DLBCL.

No MeSH data available.


Related in: MedlinePlus