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Case Report: melanoma and melanocytic nevus differentiation with reflectance confocal microscopy.

Łudzik J, Witkowski AM, Pellacani G - F1000Res (2015)

Bottom Line: Historically, melanoma has been typically diagnosed by naked-eye examination and confirmed with invasive biopsy.However, recently the use of reflectance confocal microscopy enables non-invasive bedside diagnosis of clinically equivocal lesions.We present a case in which reflectance confocal microscopy was used to evaluate two skin lesions in the same patient confirming the diagnosis of a melanoma and potentially avoiding invasive biopsy in the second benign melanocytic lesion.  Clinicians should be aware of the availability of new non-invasive technologies that can aid in early diagnosis of malignant skin tumors and potentially reduce the number of benign lesion excisions.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, University of Modena and Reggio Emilia, Modena, 41124, Italy ; Department of Biostatistics and Telemedicine, Jagiellonian University Medical College, Krakow, 31-530, Poland.

ABSTRACT
Historically, melanoma has been typically diagnosed by naked-eye examination and confirmed with invasive biopsy. However, recently the use of reflectance confocal microscopy enables non-invasive bedside diagnosis of clinically equivocal lesions. We present a case in which reflectance confocal microscopy was used to evaluate two skin lesions in the same patient confirming the diagnosis of a melanoma and potentially avoiding invasive biopsy in the second benign melanocytic lesion.  Clinicians should be aware of the availability of new non-invasive technologies that can aid in early diagnosis of malignant skin tumors and potentially reduce the number of benign lesion excisions.

No MeSH data available.


Related in: MedlinePlus

Melanoma and dysplastic nevus.A. Clinical overview of the patient.B. Lesion 1: Melanoma - naked-eye clinical close-up.C. Lesion 1: Melanoma - digital dermoscopy view.D. Lesion 2: Dysplastic nevus - naked-eye clinical close-up.E. Lesion 2: Dysplastic nevus - digital dermoscopy view.
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f1: Melanoma and dysplastic nevus.A. Clinical overview of the patient.B. Lesion 1: Melanoma - naked-eye clinical close-up.C. Lesion 1: Melanoma - digital dermoscopy view.D. Lesion 2: Dysplastic nevus - naked-eye clinical close-up.E. Lesion 2: Dysplastic nevus - digital dermoscopy view.

Mentions: The patient presented with a high numerosity of multiple irregularly shaped nevi located mainly on the back and lower legs. Lesion number 1, located on the upper right back, presented with ABCD (asymmetry, irregular borders, multiple colors, diameter >6mm) positive criteria and was of highest concern as it was the largest solitary macule on the back. Lesion number 2, located on the upper left shoulder, also presented with ABCD (asymmetry, irregular borders, multiple colors, diameter >6mm) positive criteria (Figure 1A, B, D).


Case Report: melanoma and melanocytic nevus differentiation with reflectance confocal microscopy.

Łudzik J, Witkowski AM, Pellacani G - F1000Res (2015)

Melanoma and dysplastic nevus.A. Clinical overview of the patient.B. Lesion 1: Melanoma - naked-eye clinical close-up.C. Lesion 1: Melanoma - digital dermoscopy view.D. Lesion 2: Dysplastic nevus - naked-eye clinical close-up.E. Lesion 2: Dysplastic nevus - digital dermoscopy view.
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4513693&req=5

f1: Melanoma and dysplastic nevus.A. Clinical overview of the patient.B. Lesion 1: Melanoma - naked-eye clinical close-up.C. Lesion 1: Melanoma - digital dermoscopy view.D. Lesion 2: Dysplastic nevus - naked-eye clinical close-up.E. Lesion 2: Dysplastic nevus - digital dermoscopy view.
Mentions: The patient presented with a high numerosity of multiple irregularly shaped nevi located mainly on the back and lower legs. Lesion number 1, located on the upper right back, presented with ABCD (asymmetry, irregular borders, multiple colors, diameter >6mm) positive criteria and was of highest concern as it was the largest solitary macule on the back. Lesion number 2, located on the upper left shoulder, also presented with ABCD (asymmetry, irregular borders, multiple colors, diameter >6mm) positive criteria (Figure 1A, B, D).

Bottom Line: Historically, melanoma has been typically diagnosed by naked-eye examination and confirmed with invasive biopsy.However, recently the use of reflectance confocal microscopy enables non-invasive bedside diagnosis of clinically equivocal lesions.We present a case in which reflectance confocal microscopy was used to evaluate two skin lesions in the same patient confirming the diagnosis of a melanoma and potentially avoiding invasive biopsy in the second benign melanocytic lesion.  Clinicians should be aware of the availability of new non-invasive technologies that can aid in early diagnosis of malignant skin tumors and potentially reduce the number of benign lesion excisions.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, University of Modena and Reggio Emilia, Modena, 41124, Italy ; Department of Biostatistics and Telemedicine, Jagiellonian University Medical College, Krakow, 31-530, Poland.

ABSTRACT
Historically, melanoma has been typically diagnosed by naked-eye examination and confirmed with invasive biopsy. However, recently the use of reflectance confocal microscopy enables non-invasive bedside diagnosis of clinically equivocal lesions. We present a case in which reflectance confocal microscopy was used to evaluate two skin lesions in the same patient confirming the diagnosis of a melanoma and potentially avoiding invasive biopsy in the second benign melanocytic lesion.  Clinicians should be aware of the availability of new non-invasive technologies that can aid in early diagnosis of malignant skin tumors and potentially reduce the number of benign lesion excisions.

No MeSH data available.


Related in: MedlinePlus